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ARP/wARP: Crystallographic Macromolecular Model Building Version 7.5

Builds proteins, RNA/DNA, secondary structure, side chains, loops, solvent and ligands.

Download available for Mac and Linux.

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Model building also available over the web.

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Recent Literature


Current developers

  • Victor Lamzin
  • Daria Beshnova
  • Philipp Heuser
  • Joana Pereira
  • Ioan Vancea
  • Tim Wiegels

Former developers

  • Ciarán Carolan
  • Serge Cohen
  • Zbyszek Dauter
  • Helene Doerksen
  • Guillaume Evrard
  • Francisco Fernandez
  • Johan Hattne
  • Saul Hazledine
  • Marouane Jelloul
  • Krista Joosten
  • Matheos Kakaris
  • Olga Kirillova
  • Gerrit Langer
  • Wijnand Mooij
  • Richard Morris
  • Venkat Parthasarathy
  • Anastassis Perrakis
  • Tilo Strutz
  • Keith Wilson
  • Peter Zwart

Earlier publications

  • Cohen, S.X., Jelloul M.B., Long, F., Vagin, A., Knipscheer, P., Lebbink, J., Sixma, T.K., Lamzin, V.S., Murshudov, G.N. & Perrakis, A. (2008) ARP/wARP and molecular replacement: the next generation, Acta Cryst. D64, 49-60 Abstract
  • Evrard, G.X., Langer, G.G., Perrakis, A. & Lamzin, V.S. (2007) Assessment of automatic ligand building in ARP/wARP. Acta Crystallogr. D63, 108-117 Abstract
  • Zwart, P.H., Langer, G.G. & Lamzin, V.S. (2004) Modelling bound ligands in protein crystal structures. Acta Crystallogr. D60, 2230-2239 Abstract
  • Cohen, S.X., Morris, R.J., Fernandez, F.J., Jelloul, M. Ben, Kakaris, M., Parthasarathy, V., Lamzin, V.S., Kleywegt, G.J. & Perrakis, A. (2004) Towards complete validated models in the next generation of ARP/wARP. Acta Crystallogr. D60, 2222-2229 Abstract
  • Morris, R.J., Zwart, P.H., Cohen, S., Fernandez, F.J., Kakaris, M., Kirillova, O., Vonrhein, C., Perrakis, A. & Lamzin, V.S. (2004) Breaking good resolutions with ARP/wARP. J. Synchr. Rad. 11, 56-59 Abstract
  • Morris, R.J., Perrakis, A. & Lamzin, V.S. (2003) ARP/wARP and automatic interpretation of protein electron density maps. In Meth. Enz. (Carter, C. & Sweet, B. eds.) 374, 229-244
  • Morris, R.J., Perrakis, A. & Lamzin, V.S. (2002) ARP/wARP's model-building algorithms. I. The main chain. Acta Cryst. D58, 968-975 Abstract
  • Perrakis, A., Harkiolaki, M., Wilson, K.S. & Lamzin, V.S. (2001) ARP/wARP and molecular replacement. Acta Cryst. D57, 1445-1450 Abstract
  • Lamzin, V.S., Perrakis, A. & Wilson, K.S. (2001) The ARP/WARP suite for automated construction and refinement of protein models. In Int. Tables for Crystallography. Vol. F: Crystallography of biological macromolecules (Rossmann, M.G. & Arnold, E. eds.), Dordrecht, Kluwer Academic Publishers, The Netherlands, pp. 720-722
  • Lamzin, V.S. & Perrakis, A. (2000) Current state of automated crystallographic data analysis. Nature Struct. Biol. 7, Structural Genomics Supplement, 978-981 Abstract
  • Perrakis, A., Morris, R.M. & Lamzin, V.S. (1999) Automated protein model building combined with iterative structure refinement. Nature Struct. Biol. 6, 458-463 Abstract
  • Perrakis, A., Sixma, T.K., Wilson K.S. & Lamzin, V.S. (1997) wARP: improvement and extension of crystallographic phases by weighted averaging of multiple refined dummy atomic models. Acta Cryst. D53, 448-455 Abstract
  • Lamzin, V.S. & Wilson, K.S. (1997) Automated refinement for protein crystallography. In Meth. Enz. (Carter, C. & Sweet, B. eds.) 277, 269-305
  • Lamzin, V.S. & Wilson, K.S. (1993) Automated refinement of protein models. Acta Cryst. D49, 129-147 Abstract

ARP/wARP performance