EMBL Hamburg c/o DESY, Notkestraße 85, 22607 Hamburg, Germany


  • PhD 1987, Moscow State University.
    Scientist, Inst. Biochemistry, Russian Academy of Sciences, Moscow, until 1991.
    Postdoctoral research at EMBL Hamburg until 1995.
    Staff scientist until 1997.
    Group leader since 1997.
    Senior scientist since 2003.


Total: 108 publication(s)


Petrova OA, Mantsyzov AB, Rodina EV, Efimov SV, Hackenberg C, Hakanpää J, Klochkov VV, Lebedev AA, Chugunova AA, Malyavko AN, Zatsepin TS, Mishin AV, Zvereva MI, Lamzin VS, Dontsova OA, Polshakov VI. (2018)

Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.

Nucleic Acids Res. doi: 10.1093/nar/gkx1275
Europe PMC | doi


Pereira J, Lamzin VS. (2017)

A distance geometry-based description and validation of protein main-chain conformation.

IUCrJ 4(Pt 5):657-670. doi: 10.1107/S2052252517008466
Europe PMC | doi

Antipin RL, Beshnova DA, Petrov RA, Shiryaeva AS, Andreeva IP, Grigorenko VG, Rubtsova MY, Majouga AG, Lamzin VS, Egorov AM. (2017)

Synthesis, SAR and molecular docking study of novel non-β-lactam inhibitors of TEM type β-lactamase.

Bioorg. Med. Chem. Lett. 27(7):1588-1592. doi: 10.1016/j.bmcl.2017.02.025
Europe PMC | doi

Beshnova DA, Pereira J, Lamzin VS. (2017)

Estimation of the protein-ligand interaction energy for model building and validation.

Acta Crystallogr D Struct Biol 73(Pt 3):195-202. doi: 10.1107/s2059798317003400
Europe PMC | doi

Grigorenko V., Andreeva I., Rubtsova M., Deygen I., Antipin R., Majouga A., Egorov A., Beshnova D., Kallio J., Hackenberg C., Lamzin V.. (2017)

Novel non-β-lactam inhibitor of β-lactamase TEM-171 based on acylated phenoxyaniline

Biochimie 132:45-53. doi: 10.1016/j.biochi.2016.10.011
Europe PMC | doi


Giewekemeyer K, Hackenberg C, Aquila A, Wilke RN, Groves MR, Jordanova R, Lamzin VS, Borchers G, Saksl K, Zozulya AV, Sprung M, Mancuso AP. (2015)

Tomography of a Cryo-immobilized Yeast Cell Using Ptychographic Coherent X-Ray Diffractive Imaging.

Biophys. J. 109(9):1986-1995. doi: 10.1016/j.bpj.2015.08.047
Europe PMC | doi


Carolan CG, Lamzin VS. (2014)

Automated identification of crystallographic ligands using sparse-density representations.

Acta Crystallogr. D Biol. Crystallogr. 70(Pt 7):1844-1853. doi: 10.1107/s1399004714008578
Europe PMC | doi

Petrova OA, Smekalova EM, Zvereva ME, Lamzin V, Dontsova OA. (2014)

Identification of additional telomerase component of the yeast H. polymorpha is a step towards understanding the complex at the atomic level.

Dokl. Biochem. Biophys. 455(1):59-64. doi: 10.1134/s1607672914020057
Europe PMC | doi

Ponomarenko N, Chatziefthimiou SD, Kurkova I, Mokrushina Y, Mokrushina Y, Stepanova A, Smirnov I, Avakyan M, Bobik T, Mamedov A, Mitkevich V, Belogurov A Jr, Fedorova OS, Dubina M, Golovin A, Lamzin V, Friboulet A, Makarov AA, Wilmanns M, Gabibov A. (2014)

Role of κ→λ light-chain constant-domain switch in the structure and functionality of A17 reactibody

Acta Crystallogr. D Biol. Crystallogr. 70(Pt 3):708-719. doi: 10.1107/s1399004713032446
Europe PMC | doi

Pereira J, Wiegels T, Lamzin V. (2014)

On the Validation of Fragments During Automated Protein Model Building

Pereira J, Wiegels T, Lamzin V. (2014)

ValiFrag: are these proper folds? Evaluating fragment quality during automated protein model building


Grigorenko V, Rubtsova М, Egorov А, Carolan C, Lamzin V. (2013)

Creation of recombinant strains of e-coli producing betalactamases. Study of catalytic properties and search for new beta lactamase inhibitors to overcome bacterial resistance.

RFBR Journal 4:42-46.

Zvereva М, Petrova O, Parfenova U, Smekalova Е, Malyavko А, Rodina Е, Kallio J, Hackenberg C, Wiegels Т, Lamzin V, Dontsova О. (2013)

Towards Atomic Structure of Telomerase Complex Components in Order to Create Regulators to Control Growth of Cancer Cells.

RFBR Journal 4:33-37.

Langer GG, Hazledine S, Wiegels T, Carolan C, Lamzin VS. (2013)

Visual automated macromolecular model building

Acta Crystallogr. D Biol. Crystallogr. 69(Pt 4):635-641. doi: 10.1107/s0907444913000565
Europe PMC | doi


Mancuso AP, Groves MR, Polozhentsev OE, Williams GJ, McNulty I, Antony C, Santarella-Mellwig R, Soldatov AV, Lamzin V, Peele AG, Nugent KA, Vartanyants IA. (2012)

Internal structure of an intact Convallaria majalis pollen grain observed with X-ray Fresnel coherent diffractive imaging

Opt Express 20(24):26778-26785. doi: 10.1364/oe.20.026778
Europe PMC | doi

Fedorova TV, Chulkin AM, Vavilova EA, Maisuradze IG, Trofimov AA, Zorov IN, Khotchenkov VP, Polyakov KM, Benevolensky SV, Koroleva OV, Lamzin VS. (2012)

Purification, biochemical characterization, and structure of recombinant endo-1,4-β-xylanase XylE

Biochemistry Mosc. 77(10):1190-1198. doi: 10.1134/s0006297912100112
Europe PMC | doi

Langer GG, Evrard GX, Carolan CG, Lamzin VS. (2012)

Fragmentation-tree density representation for crystallographic modelling of bound ligands

J. Mol. Biol. 419(3-4):211-222. doi: 10.1016/j.jmb.2012.03.012
Europe PMC | doi

Wiegels T, Lamzin VS. (2012)

Use of noncrystallographic symmetry for automated model building at medium to low resolution

Acta Crystallogr. D Biol. Crystallogr. 68(Pt 4):446-453. doi: 10.1107/s0907444911050712
Europe PMC | doi

Urusova DV, Isupov MN, Antonyuk S, Kachalova GS, Obmolova G, Vagin AA, Lebedev AA, Burenkov GP, Dauter Z, Bartunik HD, Lamzin VS, Melik-Adamyan WR, Mueller TD, Schnackerz KD. (2012)

Crystal structure of D-serine dehydratase from Escherichia coli

Biochim. Biophys. Acta 1824(3):422-432. doi: 10.1016/j.bbapap.2011.10.017
Europe PMC | doi

Wrenger C, Muller IB, Silber AM, Jordanova R, Lamzin VS, Groves MR. (2012)

Aspartate aminotransferase: bridging carbohydrate and energy metabolism in Plasmodium falciparum

Curr. Drug Metab. 13(3):332-336. doi: 10.2174/138920012799320400
Europe PMC | doi

Lamzin VS, Perrakis A, Wilson KS. (2012)

ARP/wARP – automated model building and refinement

doi: 10.1107/97809553602060000862
Europe PMC | doi


Unge J, Mueller-Dieckmann C, Panjikar S, Tucker PA, Lamzin VS, Weiss MS. (2011)

On the routine use of soft X-rays in macromolecular crystallography. Part V. Molecular replacement and anomalous scattering

Acta Crystallogr. D Biol. Crystallogr. 67(Pt 8):729-738. doi: 10.1107/s0907444911024887
Europe PMC | doi

Schmidt A, Teeter M, Weckert E, Lamzin VS. (2011)

Crystal structure of small protein crambin at 0.48 A resolution

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 67(Pt 4):424-428. doi: 10.1107/s1744309110052607
Europe PMC | doi

Hattne J, Lamzin VS. (2011)

A moment invariant for evaluating the chirality of three-dimensional objects

J R Soc Interface 8(54):144-151. doi: 10.1098/rsif.2010.0297
Europe PMC | doi


Watts D, Müller-Dieckmann J, Tsakanova G, Lamzin VS, Groves MR. (2010)

Quantitive evaluation of macromolecular crystallization experiments using 1,8-ANS fluorescence

Acta Crystallogr. D Biol. Crystallogr. 66(Pt 8):901-908. doi: 10.1107/s0907444910020664
Europe PMC | doi

Schmidt A, Lamzin VS. (2010)

Internal motion in protein crystal structures

Protein Sci. 19(5):944-953. doi: 10.1002/pro.371
Europe PMC | doi


Panjikar S, Parthasarathy V, Lamzin VS, Weiss MS, Tucker PA. (2009)

On the combination of molecular replacement and single-wavelength anomalous diffraction phasing for automated structure determination

Acta Crystallogr. D Biol. Crystallogr. 65(Pt 10):1089-1097. doi: 10.1107/s0907444909029643
Europe PMC | doi

Heuser P, Langer GG, Lamzin VS. (2009)

Interpretation of very low resolution X-ray electron-density maps using core objects

Paper presented at the Workshop on New Algorithms in Macromolecular Crystallography and Electron Microscopy, Leiden, NETHERLANDS, MAY 12-18, 2008.Acta Crystallogr. D Biol. Crystallogr. 65(Pt 7):690-696. doi: 10.1107/s090744490901991x
Europe PMC | doi

Polyakov KM, Boyko KM, Tikhonova TV, Slutsky A, Antipov AN, Zvyagilskaya RA, Popov AN, Bourenkov GP, Lamzin VS, Popov VO. (2009)

High-resolution structural analysis of a novel octaheme cytochrome c nitrite reductase from the haloalkaliphilic bacterium Thioalkalivibrio nitratireducens

J. Mol. Biol. 389(5):846-862. doi: 10.1016/j.jmb.2009.04.037
Europe PMC | doi

Polyakov KM, Fedorova TV, Stepanova EV, Cherkashin EA, Kurzeev SA, Strokopytov BV, Lamzin VS, Koroleva OV. (2009)

Structure of native laccase from Trametes hirsuta at 1.8 A resolution

Acta Crystallogr. D Biol. Crystallogr. 65(Pt 6):611-617. doi: 10.1107/s0907444909011950
Europe PMC | doi

Jordanova R, Lamzin VS, Groves MR. (2009)

Crystal Identification and Classification

Nova Science Publishers, USA.Astrophysics and Condensed Matter 175-193.
Europe PMC


Faust A, Panjikar S, Mueller U, Parthasarathy V, Schmidt A, Lamzin VS, Weiss MS. (2008)

A tutorial for learning and teaching macromolecular crystallography

J APPL CRYSTALLOGR 41:1161-1172. doi: 10.1107/S0021889808032494

Hattne J, Lamzin VS. (2008)

Pattern-recognition-based detection of planar objects in three-dimensional electron-density maps

Acta Crystallogr. D Biol. Crystallogr. D64(Pt 8):834-842. doi: 10.1107/s0907444908014327
Europe PMC | doi

Schmidt A, Gruber K, Kratky C, Lamzin VS. (2008)

Atomic resolution crystal structures and quantum chemistry meet to reveal subtleties of hydroxynitrile lyase catalysis

J. Biol. Chem. 283(31):21827-21836. doi: 10.1074/jbc.m801056200
Europe PMC | doi

Manicka S, Peleg Y, Unger T, Albeck S, Dym O, Greenblatt HM, Bourenkov G, Lamzin V, Krishnaswamy S, Sussman JL. (2008)

Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12

Proteins 71(4):2102-2108. doi: 10.1002/prot.22023
Europe PMC | doi

Joosten K, Cohen SX, Emsley P, Mooij W, Lamzin VS, Perrakis A. (2008)

A knowledge-driven approach for crystallographic protein model completion

Acta Crystallogr. D Biol. Crystallogr. 64(Pt 4):416-424. doi: 10.1107/s0907444908001558
Europe PMC | doi

Cohen SX, Ben Jelloul M, Long F, Vagin A, Knipscheer P, Lebbink J, Sixma TK, Lamzin VS, Murshudov GN, Perrakis A. (2008)

ARP/wARP and molecular replacement: the next generation

Acta Crystallogr. D Biol. Crystallogr. 64(Pt 1):49-60. doi: 10.1107/s0907444907047580
Europe PMC | doi

Langer G, Cohen SX, Lamzin VS, Perrakis A. (2008)

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

Nat Protoc 3(7):1171-1179. doi: 10.1038/nprot.2008.91
Europe PMC | doi


Schmidt A, Lamzin VS. (2007)

From atoms to proteins

Cell. Mol. Life Sci. 64(15):1959-1969. doi: 10.1007/s00018-007-7195-7
Europe PMC | doi

Schirwitz K, Schmidt A, Lamzin VS. (2007)

High-resolution structures of formate dehydrogenase from Candida boidinii

Protein Sci. 16(6):1146-1156. doi: 10.1110/ps.062741707
Europe PMC | doi

Meijers R, Adolph HW, Dauter Z, Wilson KS, Lamzin VS, Cedergren-Zeppezauer ES. (2007)

Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase

Biochemistry 46(18):5446-5454. doi: 10.1021/bi6023594
Europe PMC | doi

Evrard GX, Langer GG, Perrakis A, Lamzin VS. (2007)

Assessment of automatic ligand building in ARP/wARP

Acta Crystallogr. D Biol. Crystallogr. 63(Pt 1):108-117. doi: 10.1107/s0907444906023389
Europe PMC | doi


Lyashenko AV, Bento I, Zaitsev VN, Zhukhlistova NE, Zhukova YN, Gabdoulkhakov AG, Morgunova EY, Voelter W, Kachalova GS, Stepanova EV, Koroleva OV, Lamzin VS, Tishkov VI, Betzel C, Lindley PF, Mikhailov AM. (2006)

X-ray structural studies of the fungal laccase from Cerrena maxima

J. Biol. Inorg. Chem. 11(8):963-973. doi: 10.1007/s00775-006-0158-x
Europe PMC | doi

Pothineni SB, Strutz T, Lamzin VS. (2006)

Automated detection and centring of cryocooled protein crystals

Acta Crystallogr. D Biol. Crystallogr. 62(Pt 11):1358-1368. doi: 10.1107/s0907444906031672
Europe PMC | doi

Bahar M, Ballard C, Cohen SX, Cowtan KD, Dodson EJ, Emsley P, Esnouf RM, Keegan R, Lamzin V, Langer G, Levdikov V, Long F, Meier C, Muller A, Murshudov GN, Perrakis A, Siebold C, Stein N, Turkenburg MG, Vagin AA, Winn M, Winter G, Wilson KS. (2006)

SPINE workshop on automated X-ray analysis: a progress report

Acta Crystallogr. D Biol. Crystallogr. 62(Pt 10):1170-1183. doi: 10.1107/s0907444906032197
Europe PMC | doi

Lyashenko AV, Zhukhlistova NE, Gabdoulkhakov AG, Zhukova YN, Voelter W, Zaitsev VN, Bento I, Stepanova EV, Kachalova GS, Koroleva OV, Cherkashyn EA, Tishkov VI, Lamzin VS, Schirwitz K, Morgunova EY, Betzel C, Lindley PF, Mikhailov AM. (2006)

Purification, crystallization and preliminary X-ray study of the fungal laccase from Cerrena maxima

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62(Pt 10):954-957. doi: 10.1107/s1744309106036578
Europe PMC | doi

Kauffmann B, Weiss MS, Lamzin VS, Schmidt A. (2006)

How to avoid premature decay of your macromolecular crystal: a quick soak for long life

Structure 14(7):1099-1105. doi: 10.1016/j.str.2006.05.015
Europe PMC | doi

Boyko KM, Polyakov KM, Tikhonova TV, Slutsky A, Antipov AN, Zvyagilskaya RA, Bourenkov GP, Popov AN, Lamzin VS, Popov VO. (2006)

Crystallization and preliminary X-ray analysis of cytochrome c nitrite reductase from Thioalkalivibrio nitratireducens

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 62(Pt 3):215-217. doi: 10.1107/s174430910600296x
Europe PMC | doi

Urusova DV, Levdikov VM, Antonyuk SV, Grebenko AI, Lamzin VS, Melik-Adamyan VR. (2006)

X-ray diffraction study of the complex of the enzyme SAICAR synthase with the reaction product

Crystallography Reports 51(5):824-827.
Europe PMC


Schmidt A, Lamzin VS. (2005)

Extraction of functional motion in trypsin crystal structures

Acta Crystallogr. D Biol. Crystallogr. 61(Pt 8):1132-1139. doi: 10.1107/s0907444905016732
Europe PMC | doi

Panjikar S, Parthasarathy V, Lamzin VS, Weiss MS, Tucker PA. (2005)

Auto-rickshaw: an automated crystal structure determination platform as an efficient tool for the validation of an X-ray diffraction experiment

Acta Crystallogr. D Biol. Crystallogr. 61(Pt 4):449-457. doi: 10.1107/s0907444905001307
Europe PMC | doi


Cohen SX, Morris RJ, Fernandez FJ, Ben Jelloul M, Kakaris M, Parthasarathy V, Lamzin VS, Kleywegt GJ, Perrakis A. (2004)

Towards complete validated models in the next generation of ARP/wARP

Acta Crystallogr. D Biol. Crystallogr. 60(Pt 12 Pt 1):2222-2229. doi: 10.1107/s0907444904027556
Europe PMC | doi

Zwart PH, Langer GG, Lamzin VS. (2004)

Modelling bound ligands in protein crystal structures

Acta Crystallogr. D Biol. Crystallogr. 60(Pt 12 Pt 1):2230-2239. doi: 10.1107/s0907444904012995
Europe PMC | doi

Meijers R, Blagova EV, Levdikov VM, Rudenskaya GN, Chestukhina GG, Akimkina TV, Kostrov SV, Lamzin VS, Kuranova IP. (2004)

The crystal structure of glutamyl endopeptidase from Bacillus intermedius reveals a structural link between zymogen activation and charge compensation

Biochemistry 43(10):2784-2791. doi: 10.1021/bi035354s
Europe PMC | doi

Zwart PH, Lamzin VS. (2004)

The influence of positional errors on the Debye effects

Acta Crystallogr. D Biol. Crystallogr. 60(Pt 2):220-226. doi: 10.1107/s0907444903025526
Europe PMC | doi

Morris RJ, Zwart PH, Cohen S, Fernandez FJ, Kakaris M, Kirillova O, Vonrhein C, Perrakis A, Lamzin VS. (2004)

Breaking good resolutions with ARP/wARP

Paper presented at the International Symposium on Diffraction Structural Biology (ISDSB2003), TSUKUBA, JAPAN, MAY 28-JUN 02, 2003.J Synchrotron Radiat 11(Pt 1):56-59.
Europe PMC


Zwart PH, Lamzin VS. (2003)

Distance distributions and electron-density characteristics of protein models

Acta Crystallogr. D Biol. Crystallogr. 59(Pt 12):2104-2113. doi: 10.1107/s0907444903018596
Europe PMC | doi

Schmidt A, Jelsch C, Ostergaard P, Rypniewski W, Lamzin VS. (2003)

Trypsin revisited: crystallography AT (SUB) atomic resolution and quantum chemistry revealing details of catalysis

J. Biol. Chem. 278(44):43357-43362. doi: 10.1074/jbc.m306944200
Europe PMC | doi

Pegasova TV, Zwart P, Koroleva OV, Stepanova EV, Rebrikov DV, Lamzin VS. (2003)

Crystallization and preliminary X-ray analysis of a four-copper laccase from Coriolus hirsutus

Acta Crystallogr. D Biol. Crystallogr. 59(Pt 8):1459-1461. doi: 10.1107/s0907444903011521
Europe PMC | doi

Morris RJ, Perrakis A, Lamzin VS. (2003)

ARP/wARP and automatic interpretation of protein electron density maps

Meth. Enzymol. 374:229-244. doi: 10.1016/s0076-6879(03)74011-7
Europe PMC | doi

Terwilliger TC, Park MS, Waldo GS, Berendzen J, Hung LW, Kim CY, Smith CV, Sacchettini JC, Bellinzoni M, Bossi R, De Rossi E, Mattevi A, Milano A, Riccardi G, Rizzi M, Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP, Goulding CW, Apostol MI, Anderson DH, Gill HS, Eisenberg DS, Taneja B, Mande S, Pohl E, Lamzin V, Tucker P, Wilmanns M, Colovos C, Meyer-Klaucke W, Munro AW, McLean KJ, Marshall KR, Leys D, Yang JK, Yoon HJ, Lee BI, Lee MG, Kwak JE, Han BW, Lee JY, Baek SH, Suh SW, Komen MM, Arcus VL, Baker EN, Lott JS, Jacobs W Jr, Alber T, Rupp B. (2003)

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology

Tuberculosis (Edinb) 83(4):223-249. doi: 10.1016/s1472-9792(03)00051-9
Europe PMC | doi


Schmidt A, Lamzin VS. (2002)

Veni, vidi, vici - atomic resolution unravelling the mysteries of protein function

Curr. Opin. Struct. Biol. 12(6):698-703. doi: 10.1016/s0959-440x(02)00394-9
Europe PMC | doi

Schmidt A, Gonzalez A, Morris RJ, Costabel M, Alzari PM, Lamzin VS. (2002)

Advantages of high-resolution phasing: MAD to atomic resolution

Acta Crystallogr. D Biol. Crystallogr. 58(Pt 9):1433-1441. doi: 10.1107/s0907444902011368
Europe PMC | doi

Sevcík J, Lamzin VS, Dauter Z, Wilson KS. (2002)

Atomic resolution data reveal flexibility in the structure of RNase Sa

Acta Crystallogr. D Biol. Crystallogr. 58(Pt 8):1307-1313.
Europe PMC

Morris RJ, Perrakis A, Lamzin VS. (2002)

ARP/wARP's model-building algorithms. I. The main chain

Acta Crystallogr. D Biol. Crystallogr. 58(Pt 6 Pt 2):968-975. doi: 10.1107/s0907444902005462
Europe PMC | doi

Razeto A, Kochhar S, Hottinger H, Dauter M, Wilson KS, Lamzin VS. (2002)

Domain closure, substrate specificity and catalysis of D-lactate dehydrogenase from Lactobacillus bulgaricus

J. Mol. Biol. 318(1):109-119. doi: 10.1016/s0022-2836(02)00086-4
Europe PMC | doi

Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L. (2002)

Atomic resolution structures of ribonuclease A at six pH values

Acta Crystallogr. D Biol. Crystallogr. 58(Pt 3):441-450. doi: 10.1107/s0907444901021758
Europe PMC | doi

Guérin DM, Lascombe MB, Costabel M, Souchon H, Lamzin V, Béguin P, Alzari PM. (2002)

Atomic (0.94 A) resolution structure of an inverting glycosidase in complex with substrate

J. Mol. Biol. 316(5):1061-1069. doi: 10.1006/jmbi.2001.5404
Europe PMC | doi

Galkin AG, Kutsenko AS, Bajulina NP, Esipova NG, Lamzin VS, Mesentsev AV, Shelukho DV, Tikhonova TV, Tishkov VI, Ustinnikova TB, Popov VO. (2002)

Site-directed mutagenesis of the essential arginine of the formate dehydrogenase active centre

Biochim. Biophys. Acta 1594(1):136-149. doi: 10.1016/s0167-4838(01)00297-7
Europe PMC | doi


Samygina VR, Popov AN, Rodina EV, Vorobyeva NN, Lamzin VS, Polyakov KM, Kurilova SA, Nazarova TI, Avaeva SM. (2001)

The structures of Escherichia coli inorganic pyrophosphatase complexed with Ca(2+) or CaPP(i) at atomic resolution and their mechanistic implications

J. Mol. Biol. 314(3):633-645. doi: 10.1006/jmbi.2001.5149
Europe PMC | doi

Perrakis A, Harkiolaki M, Wilson KS, Lamzin VS. (2001)

ARP/wARP and molecular replacement

Acta Crystallogr. D Biol. Crystallogr. 57(Pt 10):1445-1450. doi: 10.1107/s0907444901014007
Europe PMC | doi

Barynin VV, Whittaker MM, Antonyuk SV, Lamzin VS, Harrison PM, Artymiuk PJ, Whittaker JW. (2001)

Crystal structure of manganese catalase from Lactobacillus plantarum

Structure 9(8):725-738. doi: 10.1016/s0969-2126(01)00628-1
Europe PMC | doi

Tishchenko S, Nikulin A, Fomenkova N, Nevskaya N, Nikonov O, Dumas P, Moine H, Ehresmann B, Ehresmann C, Piendl W, Lamzin V, Garber M, Nikonov S. (2001)

Detailed analysis of RNA-protein interactions within the ribosomal protein S8-rRNA complex from the archaeon Methanococcus jannaschii

J. Mol. Biol. 311(2):311-324. doi: 10.1006/jmbi.2001.4877
Europe PMC | doi

Makedonopoulou S, Yannakopoulou K, Mentzafos D, Lamzin V, Popov A, Mavridis IM. (2001)

Non-covalent interactions in the crystallization of the enantiomers of 1,7-dioxaspiro

Acta Crystallogr., B 57(Pt 3):399-409. doi: 10.1107/s0108768101001963
Europe PMC | doi

Lamzin, VS; Perrakis, A.; Wilson, K.S. (2001)

The ARP/wARP suite for automated construction and refinement of protein models

International Tables for Crystallography 720-722.

Grabarse W, Mahlert F, Duin EC, Goubeaud M, Shima S, Thauer RK, Lamzin V, Ermler U. (2001)

On the mechanism of biological methane formation: structural evidence for conformational changes in methyl-coenzyme M reductase upon substrate binding

J. Mol. Biol. 309(1):315-330. doi: 10.1006/jmbi.2001.4647
Europe PMC | doi

Meijers R, Morris RJ, Adolph HW, Merli A, Lamzin VS, Cedergren-Zeppezauer ES. (2001)

On the enzymatic activation of NADH

J. Biol. Chem. 276(12):9316-9321. doi: 10.1074/jbc.m010870200
Europe PMC | doi

Sebastião MP, Lamzin V, Saraiva MJ, Damas AM. (2001)

Transthyretin stability as a key factor in amyloidogenesis: X-ray analysis at atomic resolution

J. Mol. Biol. 306(4):733-744. doi: 10.1006/jmbi.2000.4415
Europe PMC | doi


Lamzin VS, Perrakis A. (2000)

Current state of automated crystallographic data analysis

Nat. Struct. Biol. 7 Suppl:978-981. doi: 10.1038/80763
Europe PMC | doi

Lamzin VS, Perrakis A, Bricogne G, Jiang J, Swaminathan S, Sussman JL. (2000)

Apotheosis, not apocalypse: methods in protein crystallography

Acta Crystallogr. D Biol. Crystallogr. 56(Pt 11):1510-1511. doi: 10.1107/s0907444900010751
Europe PMC | doi

Adolph HW, Zwart P, Meijers R, Hubatsch I, Kiefer M, Lamzin V, Cedergren-Zeppezauer E. (2000)

Structural basis for substrate specificity differences of horse liver alcohol dehydrogenase isozymes

Biochemistry 39(42):12885-12897. doi: 10.1021/bi001376s
Europe PMC | doi

Samygina VR, Antonyuk SV, Lamzin VS, Popov AN. (2000)

Improving the X-ray resolution by reversible flash-cooling combined with concentration screening, as exemplified with PPase

Acta Crystallogr. D Biol. Crystallogr. 56(Pt 5):595-603. doi: 10.1107/s0907444900002493
Europe PMC | doi

Jelsch C, Teeter MM, Lamzin V, Pichon-Pesme V, Blessing RH, Lecomte C. (2000)

Accurate protein crystallography at ultra-high resolution: valence electron distribution in crambin

Proc. Natl. Acad. Sci. U.S.A. 97(7):3171-3176. doi: 10.1073/pnas.97.7.3171
Europe PMC | doi

Kochhar S, Lamzin VS, Razeto A, Delley M, Hottinger H, Germond JE. (2000)

Roles of his205, his296, his303 and Asp259 in catalysis by NAD+-specific D-lactate dehydrogenase

Eur. J. Biochem. 267(6):1633-1639. doi: 10.1046/j.1432-1327.2000.01155.x
Europe PMC | doi

Antonyuk SV, Melik-Adamyan VR, Popov AN, Lamzin VS, Hempstead PD, Harrison PM, Artymyuk PJ, Barynin VV. (2000)

Three-dimensional structure of the enzyme dimanganese catalase from Thermus thermophilus at 1 angstrom resolution

Crystallography Reports 45(1):105-116.
Europe PMC


Parisini E, Capozzi F, Lubini P, Lamzin V, Luchinat C, Sheldrick GM. (1999)

Ab initio solution and refinement of two high-potential iron protein structures at atomic resolution

Acta Crystallogr. D Biol. Crystallogr. 55(Pt 11):1773-1784. doi: 10.1107/s0907444999009129
Europe PMC | doi

Berisio R, Lamzin VS, Sica F, Wilson KS, Zagari A, Mazzarella L. (1999)

Protein titration in the crystal state

J. Mol. Biol. 292(4):845-854. doi: 10.1006/jmbi.1999.3093
Europe PMC | doi

Declercq JP, Evrard C, Lamzin V, Parello J. (1999)

Crystal structure of the EF-hand parvalbumin at atomic resolution (0.91 A) and at low temperature (100 K). Evidence for conformational multistates within the hydrophobic core

Protein Sci. 8(10):2194-2204. doi: 10.1110/ps.8.10.2194
Europe PMC | doi

Lamzin VS, Morris RJ, Dauter Z, Wilson KS, Teeter MM. (1999)

Experimental observation of bonding electrons in proteins

J. Biol. Chem. 274(30):20753-20755. doi: 10.1074/jbc.274.30.20753
Europe PMC | doi

Perrakis A, Morris R, Lamzin VS. (1999)

Automated protein model building combined with iterative structure refinement

Nat. Struct. Biol. 6(5):458-463. doi: 10.1038/8263
Europe PMC | doi

Frazão C, Sieker L, Sheldrick G, Lamzin V, LeGall J, Carrondo MA. (1999)

Ab initio structure solution of a dimeric cytochrome c3 from Desulfovibrio gigas containing disulfide bridges

J. Biol. Inorg. Chem. 4(2):162-165. doi: 10.1007/s007750050299
Europe PMC | doi

Perrakis A, Antoniadou-Vyza E, Tsitsa P, Lamzin VS, Wilson KS, Hamodrakas SJ. (1999)

Molecular, crystal and solution structure of a beta-cyclodextrin complex with the bromide salt of 2-(3-dimethylaminopropyl)tricyclo[,7)]decan-2-ol, a potent antimicrobial drug

Carbohydr. Res. 317(1-4):19-28. doi: 10.1016/s0008-6215(99)00021-x
Europe PMC | doi


Walsh MA, Schneider TR, Sieker LC, Dauter Z, Lamzin VS, Wilson KS. (1998)

Refinement of triclinic hen egg-white lysozyme at atomic resolution

Acta Crystallogr. D Biol. Crystallogr. 54(Pt 4):522-546. doi: 10.1107/s0907444997013656
Europe PMC | doi

Dodson EJ, Davies GJ, Lamzin VS, Murshudov GN, Wilson KS. (1998)

Validation tools: can they indicate the information content of macromolecular crystal structures?

Structure 6(6):685-690. doi: 10.1016/s0969-2126(98)00070-7
Europe PMC | doi

Esposito L, Sica F, Sorrentino G, Berisio R, Carotenuto L, Giordano A, Raia CA, Rossi M, Lamzin VS, Wilson KS, Zagari A. (1998)

Protein crystal growth in the Advanced Protein Crystallization Facility on the LMS mission: a comparison of Sulfolobus solfataricus alcohol dehydrogenase crystals grown on the ground and in microgravity

Acta Crystallogr. D Biol. Crystallogr. 54(Pt 3):386-390. doi: 10.1107/s0907444997011992
Europe PMC | doi

Levdikov VM, Barynin VV, Grebenko AI, Melik-Adamyan WR, Lamzin VS, Wilson KS. (1998)

The structure of SAICAR synthase: an enzyme in the de novo pathway of purine nucleotide biosynthesis

Structure 6(3):363-376. doi: 10.1016/s0969-2126(98)00038-0
Europe PMC | doi

EU 3-D Validation Network. (1998)

Who checks the checkers? Four validation tools applied to eight atomic resolution structures. EU 3-D Validation Network

J. Mol. Biol. 276(2):417-436.
Europe PMC

Kutzenko AS, Lamzin VS, Popov VO. (1998)

Conserved supersecondary structural motif in NAD-dependent dehydrogenases

FEBS Lett. 423(1):105-109. doi: 10.1016/s0014-5793(98)00074-x
Europe PMC | doi

Van Asselt EJ, Perrakis A, Kalk KH, Lamzin VS, Dijkstra BW. (1998)

Accelerated X-ray structure elucidation of a 36 kDa muramidase/transglycosylase using wARP

Acta Crystallogr. D Biol. Crystallogr. 54(Pt 1):58-73. doi: 10.1107/s0907444997010330
Europe PMC | doi


Dauter Z, Lamzin VS, Wilson KS. (1997)

The benefits of atomic resolution

Curr. Opin. Struct. Biol. 7(5):681-688. doi: 10.1016/s0959-440x(97)80078-4
Europe PMC | doi