Staff at EMBL
Dr. Rob Meijers
Group Leader
Meijers Group
EMBL Hamburg c/o DESY, Notkestraße 85, 22603 Hamburg, Germany
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Biography
PhD 2001, EMBL Hamburg/University of Amsterdam.
Postdoctoral research at the Dana Farber Cancer Institute, Boston.
Staff scientist at the Synchrotron Soleil, Saint Aubin, France, 2006-2009.
Group leader at EMBL Hamburg since 2009.
Publications
Structure-based modification of a Clostridium Difficile targeting endolysin affects activity and host range. Melinda J. Mayer, Vasiliki Garefalaki, Rebecca Spoerl, Arjan Narbad and Meijers, R. J. Bact. 197 (2011) Pub ahead of print.
Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers. Grotenbreg, G.M., Roan, N.R., Guillen, E., Meijers, R., Wang, J.H., Bell, G.W., Starnbach, M.N. & Ploegh, H.L. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3831-6. Epub 2008 Feb 1. PubMed
Structural basis of Dscam isoform specificity. Meijers, R., Puettmann-Holgado, R., Skiniotis, G., Liu, J.H., Walz, T., Wang, J.H. & Schmucker, D. Nature. 2007 Sep 27;449(7161):487-91. Epub 2007 Aug 26. PubMed
Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase. Meijers, R., Adolph, H.W., Dauter, Z., Wilson, K.S., Lamzin, V.S. & Cedergren-Zeppezauer, E.S. Biochemistry. 2007 May 8;46(18):5446-54. Epub 2007 Apr 13. PubMed
Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance. Meijers, R., Lai, C.C., Yang, Y., Liu, J.H., Zhong, W., Wang, J.H. & Reinherz, E.L. J Mol Biol. 2005 Feb 4;345(5):1099-110. Epub 2004 Dec 8. PubMed
The crystal structure of glutamyl endopeptidase from Bacillus intermedius reveals a structural link between zymogen activation and charge compensation. Meijers, R., Blagova, E.V., Levdikov, V.M., Rudenskaya, G.N., Chestukhina, G.G., Akimkina, T.V., Kostrov, S.V., Lamzin, V.S. & Kuranova, I.P. Biochemistry 2004 Mar 16;43(10):2784-91. PubMed
Zn-dependent medium-chain dehydrogenases/reductases. Meijers R and Cedergen-Zeppezauer E.S. Handbook of Metalloproteins 3 (2004), pp 5-33 editors: Albrecht Messerschmidt, Wolfram Bode, Mirek Cygler, John Wiley & Sons, Ltd, Chichester.
Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family. Tan, K., Zelus, B.D., Meijers, R., Liu, J.H., Bergelson, J.M., Duke, N., Zhang, R., Joachimiak, A., Holmes, K.V. & Wang, J.H. EMBO J. 2002 May 1;21(9):2076-86. PubMed
Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule. Wang, J.H., Meijers, R., Xiong, Y., Liu, J.H., Sakihama, T., Zhang, R., Joachimiak, A. & Reinherz, E.L. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10799-804. Epub 2001 Sep 4. PubMed
On the enzymatic activation of NADH. Meijers, R., Morris, R.J., Adolph, H.W., Merli, A., Lamzin, V.S. & Cedergren-Zeppezauer, E.S. J Biol Chem 2001 Mar 23;276(12):9316-21. PubMed
Structural basis for substrate specificity differences of horse liver alcohol dehydrogenase isozymes. Adolph, H.W., Zwart, P., Meijers, R., Hubatsch, I., Kiefer, M., Lamzin, V. & Cedergren-Zeppezauer, E. Biochemistry 2000 Oct 24;39(42):12885-97 PubMed
The preliminary analysis of the three-dimensional structure of dimeric di-haem split-Soret cytochronme c from Desulfovibrio desulfuricans ATCC 27774 at 2.5 resoltuion using the MAD phasing method a novel cytochrome fold with a stacked-haem arrangement. Matias, P.M., Morais, J., Coelho, A.V., Meijers, R., Gonzalez, A., Thompson, A.W., Sieker, L., LeGall, J. & Carrondo, M.A. ??