EMBL Hamburg c/o DESY, Notkestraße 85, 22607 Hamburg, Germany

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  • PhD 2001, EMBL Hamburg/University of Amsterdam.
    Postdoctoral research at the Dana Farber Cancer Institute, Boston.
    Staff scientist at the Synchrotron Soleil, Saint Aubin, France, 2006-2009.
    Group leader at EMBL Hamburg since 2009.


Total: 28 publication(s)


Papageorgiou AC, Adam PS, Stavros P, Nounesis G, Meijers R, Petratos K, Vorgias CE. (2016)

HU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analyses.

Extremophiles doi:10.1007/s00792-016-0859-1
Europe PMC | doi

Meijers R, Perrakis A. (2016)

Editorial overview: New constructs and expression of proteins.

Curr. Opin. Struct. Biol. 38:v-vi. doi:10.1016/j.sbi.2016.07.013
Europe PMC | doi

Parret AH, Besir H, Meijers R. (2016)

Critical reflections on synthetic gene design for recombinant protein expression.

Curr. Opin. Struct. Biol. 38:155-162. doi:10.1016/j.sbi.2016.07.004
Europe PMC | doi

Kozak S, Lercher L, Karanth MN, Meijers R, Carlomagno T, Boivin S. (2016)

Optimization of protein samples for NMR using thermal shift assays.

J. Biomol. NMR doi:10.1007/s10858-016-0027-z
Europe PMC | doi

Boivin S, Kozak S, Rasmussen G, Nemtanu IM, Vieira V, Meijers R. (2016)

An integrated pipeline for sample preparation and characterization at the EMBL@PETRA3 synchrotron facilities.

Methods 95:70-77. doi:10.1016/j.ymeth.2015.08.003
Europe PMC | doi


Dunne M, Leicht S, Krichel B, Mertens HD, Thompson A, Krijgsveld J, Svergun DI, Gómez-Torres N, Garde S, Uetrecht C, Narbad A, Mayer MJ, Meijers R. (2015)

Crystal structure of the CTP1L endolysin reveals how its activity is regulated by a secondary translation product.

J. Biol. Chem. doi:10.1074/jbc.M115.671172
Europe PMC | doi

Wuerges J, Caputi L, Cianci M, Boivin S, Meijers R, Benini S. (2015)

The crystal structure of Erwinia amylovora levansucrase provides a snapshot of the products of sucrose hydrolysis trapped into the active site.

J Struct Biol doi:10.1016/j.jsb.2015.07.010
Europe PMC | doi

Kaljunen H, Schiefelbein SH, Stummer D, Kozak S, Meijers R, Christiansen G, Rentmeister A. (2015)

Structural Elucidation of the Bispecificity of A Domains as a Basis for Activating Non-natural Amino Acids.

Angew. Chem. Int. Ed. Engl. doi:10.1002/anie.201503275
Europe PMC | doi

Graewert MA, Franke D, Jeffries CM, Blanchet CE, Ruskule D, Kuhle K, Flieger A, Schäfer B, Tartsch B, Meijers R, Svergun DI. (2015)

Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions.

Sci Rep 5 doi:10.1038/srep10734
Europe PMC | doi

Schürmann M, Meijers R, Schneider TR, Steinbüchel A, Cianci M. (2015)

3-Sulfinopropionyl-coenzyme A (3SP-CoA) desulfinase from Advenella mimigardefordensis DPN7(T): crystal structure and function of a desulfinase with an acyl-CoA dehydrogenase fold.

Acta Crystallogr. D Biol. Crystallogr. 71(Pt 6):1360-1372. doi:10.1107/S1399004715006616
Europe PMC | doi

Skruzny M, Desfosses A, Prinz S, Dodonova SO, Gieras A, Uetrecht C, Jakobi AJ, Abella M, Hagen WJ, Schulz J, Meijers R, Rybin V, Briggs JA, Sachse C, Kaksonen M. (2015)

An Organized Co-assembly of Clathrin Adaptors Is Essential for Endocytosis.

Dev. Cell 33(2):150-162. doi:10.1016/j.devcel.2015.02.023
Europe PMC | doi

Finci L, Zhang Y, Meijers R, Wang JH. (2015)

Signaling mechanism of the netrin-1 receptor DCC in axon guidance.

Prog. Biophys. Mol. Biol. doi:10.1016/j.pbiomolbio.2015.04.001
Europe PMC | doi


Choo JA, Thong SY, Yap J, van Esch WJ, Raida M, Meijers R, Lescar J, Verhelst SH, Grotenbreg GM. (2014)

Bioorthogonal Cleavage and Exchange of Major Histocompatibility Complex Ligands by Employing Azobenzene-Containing Peptides.

Angew. Chem. Int. Ed. Engl. 53(49):13390-13394. doi:10.1002/anie.201406295
Europe PMC | doi

Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HD, Svergun DI, Zhang Y, Wang JH, Meijers R. (2014)

The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue

Neuron 83(4):839-849. doi:10.1016/j.neuron.2014.07.010
Europe PMC | doi

Dunne M, Mertens HD, Garefalaki V, Jeffries CM, Thompson A, Lemke EA, Svergun DI, Mayer MJ, Narbad A, Meijers R. (2014)

The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor

PLoS Pathog. 10(7):e1004228. doi:10.1371/journal.ppat.1004228
Europe PMC | doi


Boivin S, Kozak S, Meijers R. (2013)

Optimization of protein purification and characterization using Thermofluor screens

Protein Expr. Purif. 91(2):192-206. doi:10.1016/j.pep.2013.08.002
Europe PMC | doi


Mayer MJ, Garefalaki V, Spoerl R, Narbad A, Meijers R. (2011)

Structure-based modification of a Clostridium difficile-targeting endolysin affects activity and host range

J. Bacteriol. 193(19):5477-5486. doi:10.1128/jb.00439-11
Europe PMC | doi


Grotenbreg GM, Roan NR, Guillen E, Meijers R, Wang JH, Bell GW, Starnbach MN, Ploegh HL. (2008)

Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers

Proc. Natl. Acad. Sci. U.S.A. 105(10):3831-3836. doi:10.1073/pnas.0711504105
Europe PMC | doi


Meijers R, Puettmann-Holgado R, Skiniotis G, Liu JH, Walz T, Wang JH, Schmucker D. (2007)

Structural basis of Dscam isoform specificity

Nature 449(7161):487-491. doi:10.1038/nature06147
Europe PMC | doi

Meijers R, Adolph HW, Dauter Z, Wilson KS, Lamzin VS, Cedergren-Zeppezauer ES. (2007)

Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase

Biochemistry 46(18):5446-5454. doi:10.1021/bi6023594
Europe PMC | doi


Meijers R, Cedergren-Zeppezauer ES. (2006)

Zn-dependent medium-chain dehydrogenases/reductases

John Wiley & Sons, Ltd. Handbook of Metalloproteins doi:10.1002/0470028637.met001
Europe PMC | doi


Meijers R, Lai CC, Yang Y, Liu JH, Zhong W, Wang JH, Reinherz EL. (2005)

Crystal structures of murine MHC Class I H-2 D(b) and K(b) molecules in complex with CTL epitopes from influenza A virus: implications for TCR repertoire selection and immunodominance

J. Mol. Biol. 345(5):1099-1110. doi:10.1016/j.jmb.2004.11.023
Europe PMC | doi


Meijers R, Blagova EV, Levdikov VM, Rudenskaya GN, Chestukhina GG, Akimkina TV, Kostrov SV, Lamzin VS, Kuranova IP. (2004)

The crystal structure of glutamyl endopeptidase from Bacillus intermedius reveals a structural link between zymogen activation and charge compensation

Biochemistry 43(10):2784-2791. doi:10.1021/bi035354s
Europe PMC | doi


Tan K, Zelus BD, Meijers R, Liu JH, Bergelson JM, Duke N, Zhang R, Joachimiak A, Holmes KV, Wang JH. (2002)

Crystal structure of murine sCEACAM1a[1,4]: a coronavirus receptor in the CEA family

EMBO J. 21(9):2076-2086. doi:10.1093/emboj/21.9.2076
Europe PMC | doi


Wang JH, Meijers R, Xiong Y, Liu JH, Sakihama T, Zhang R, Joachimiak A, Reinherz EL. (2001)

Crystal structure of the human CD4 N-terminal two-domain fragment complexed to a class II MHC molecule

Proc. Natl. Acad. Sci. U.S.A. 98(19):10799-10804. doi:10.1073/pnas.191124098
Europe PMC | doi

Meijers R, Morris RJ, Adolph HW, Merli A, Lamzin VS, Cedergren-Zeppezauer ES. (2001)

On the enzymatic activation of NADH

J. Biol. Chem. 276(12):9316-9321. doi:10.1074/jbc.m010870200
Europe PMC | doi


Adolph HW, Zwart P, Meijers R, Hubatsch I, Kiefer M, Lamzin V, Cedergren-Zeppezauer E. (2000)

Structural basis for substrate specificity differences of horse liver alcohol dehydrogenase isozymes

Biochemistry 39(42):12885-12897. doi:10.1021/bi001376s
Europe PMC | doi


Matias PM, Morais J, Coelho AV, Meijers R, Gonzalez A, Thompson AW, Sieker L, LeGall J, Carrondo MA. (1997)

A preliminary analysis of the three-dimensional structure of dimeric di-haem split-Soret cytochrome c from Desulfovibrio desulfuricans ATCC 27774 at 2.5-Å resolution using the MAD phasing method: a novel cytochrome fold with a stacked-haem arrangement

J. Biol. Inorg. Chem. 2(4):507-514. doi:10.1007/s007750050162