Staff at EMBL

Dr. Thomas Schneider

Group Leader
Schneider (Thomas) Group

EMBL Hamburg c/o DESY, Notkestraße 85, 22603 Hamburg, Germany

Biography

PhD 1996, Technical University of Munich/EMBL.
Postdoctoral research at the MPI for Molecular Physiology, Dortmund, and the University
of Göttingen.
Group leader at the FIRC Institute of Molecular Oncology, Milan.
Group leader at EMBL since 2007. Coordinator MX@PETRA3

Publications

Synchrotron radiation: micrometer-sized x-ray beams as fine tools for macromolecular crystallography. Schneider, T.R. HFSP J. 2008 Dec;2(6):302-6. Epub 2008 Oct 17. PubMed

RAPIDO: a web server for the alignment of protein structures in the presence of conformational changes. Mosca, R. & Schneider, T.R. Nucleic Acids Res. 2008 Jul 1;36(Web Server issue):W42-6. Epub 2008 May 6. PubMed

Alignment of protein structures in the presence of domain motions. Mosca, R., Brannetti, B. & Schneider, T.R. BMC Bioinformatics. 2008 Aug 27;9:352. PubMed

The atomic resolution structure of human aldose reductase reveals that rearrangement of a bound ligand allows the opening of the safety-belt loop. Biadene, M., Hazemann, I., Cousido, A., Ginell, S., Joachimiak, A., Sheldrick, G.M., Podjarny, A. & Schneider, T.R. Acta Crystallogr D Biol Crystallogr. 2007 Jun;63(Pt 6):665-72. Epub 2007May 15. PubMed

Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin. Penengo, L., Mapelli, M., Murachelli, A.G., Confalonieri, S., Magri, L., Musacchio, A., Di Fiore, P.P., Polo, S. & Schneider, T.R. Cell. 2006 Mar 24;124(6):1183-95. Epub 2006 Feb 23. PubMed

Substructure determination in isomorphous replacement and anomalous diffraction experiments. Grosse-Kunstleve, R.W. & Schneider, T.R. Methods Mol Biol. 2006;364:197-214. PubMed

Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Sessa, F., Mapelli, M., Ciferri, C., Tarricone, C., Areces, L.B., Schneider, T.R., Stukenberg, P.T. & Musacchio, A. Mol Cell. 2005 Apr 29;18(3):379-91. PubMed

Domain identification by iterative analysis of error-scaled difference distance matrices. Schneider, T.R. Acta Crystallogr D Biol Crystallogr. 2004 Dec;60(Pt 12 Pt 1):2269-75. Epub2004 Nov 26. PubMed