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Staff at EMBL

Alexey Kikhney

Senior Technical Officer
Svergun Group

EMBL Hamburg c/o DESY, Notkestraße 85, 22603 Hamburg, Germany

E-mail: send a mail

Publications

Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae. Mellroth, P., Sandalova, T., Kikhney, A., Vilaplana, F., Hesek, D., Lee, M., Mobashery, S., Normark, S., Svergun, D., Henriques-Normark, B. & Achour, A. MBio. 2014 Feb 11;5(1):e01120-13. doi: 10.1128/mBio.01120-13. Europe PMC

Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases. Begum, A., Drebes, J., Kikhney, A., Muller, I.B., Perbandt, M., Svergun, D., Wrenger, C. & Betzel, C. Acta Crystallogr D Biol Crystallogr. 2013 Dec;69(Pt 12):2320-9. doi:10.1107/S0907444913021550. Epub 2013 Nov 19. Europe PMC

Comparative Characterization of Apo-, Reconstituted- and In Vivo-Folded forms of a Durum Wheat Metallothionein. Sayers, Z., Aydin, M., Bal, E., Yesilirmak, F., Konarev, P. V., Petoukhov, M. V., Roessle, M., Kikhney, A. G., Shang, W. & Svergun, D. I. Biophys J. 2013 Jan 29;104(2):396a. pii: S0006349512034558. doi:10.1016/j.bpj.2012.11.2209.

WeNMR: Structural Biology on the Grid. Wassenaar, T. A., van Dijk M., Loureiro-Ferreira N., van der Schot G., de Vries S. J., Schmitz C., van der Zwan J., Boelens R., Giachetti A., Ferella L., Rosato A., Bertini I., Herrmann T., Jonker H. R. A., Bagaria A., Jaravine V., Güntert P., Schwalbe H., VRANKEN W. F., Doreleijers J. F., Vriend G., Vuister G. W., d. Franke, a. Kikhney, Svergun D. I., Fogh R. H., o. Ionides J., Laue E. D., Spronk C., Jurkša S., Verlato M., Badoer S., Pra Dal S., Mazzucato M., Frizziero E. & Bonvin Amjj J. Grid. Comp. 2012. 10, 743-767. doi: 10.1007/s10723-012-9246-z.

Automated acquisition and analysis of small angle X-ray scattering data. Franke, D., Kikhney*, A.G. & Svergun, D.I. Nuclear Instruments & Methods in Physics Research Section a-Accelerators Spectrometers Detectors and Associated Equipment. 2012 Oct 10;689, 52-59. doi:10.1016/j.nima.2012.06.008
*Contributed equally to the work

Peroxisomal proteostasis involves a Lon family protein that functions as protease and chaperone. Bartoszewska, M., Williams, C., Kikhney, A., Opalinski, L., van Roermund, C.W., de Boer, R., Veenhuis, M. & van der Klei, I.J. J Biol Chem. 2012 Aug 10;287(33):27380-95. Epub 2012 Jun 25. Europe PMC

Instrumental setup for high-throughput small- and wide-angle solution scattering at the X33 beamline of EMBL Hamburg Blanchet, C.E., Zozulya, A.V., Kikhney, A.G., Franke, D., Konarev, P.V., Shang, W., Klaering, R., Robrahn, B., Hermes, C., Cipriani, F., Svergun, D.I. & Roessle, M. J. Appl. Cryst. (2012). 45, 489-495, doi:10.1107/S0021889812013490

New developments in the ATSAS program package for small-angle scattering data analysis M. V. Petoukhov, D. Franke, A. V. Shkumatov, G. Tria, A. G. Kikhney, M. Gajda, C. Gorba, H. D. T. Mertens, P. V. Konarev and D. I. Svergun J. Appl. Cryst. (2012). 45, 342-350, doi:10.1107/S0021889812007662

The switch that does not flip: the blue-light receptor YtvA from Bacillus subtilis adopts an elongated dimer conformation independent of the activation state as revealed by a combined AUC and SAXS study. Jurk, M., Dorn, M., Kikhney, A., Svergun, D., Gartner, W. & Schmieder, P. J Mol Biol. 2010 Oct 15;403(1):78-87. doi: 10.1016/j.jmb.2010.08.036. Epub 2010Aug 25. Europe PMC

ATSAS 2.1 - towards automated and web-supported small-angle scattering data analysis. Petoukhov, M.V., Konarev, P.V., Kikhney, A.G. & Svergun, D.I. Journal of Applied Crystallography 2007 40 S223-S228