EMBL Hamburg c/o DESY, Notkestraße 85, 22607 Hamburg, Germany


Total: 20 publication(s)


Falke S, Dierks K, Blanchet C, Graewert M, Cipriani F, Meijers R, Svergun D, Betzel C. (2018)

Multi-channel in situ dynamic light scattering instrumentation enhancing biological small-angle X-ray scattering experiments at the PETRA III beamline P12.

J Synchrotron Radiat 25(Pt 2):361-372. doi: 10.1107/S1600577517017568
Europe PMC | doi


Graewert MA, Jeffries CM. (2017)

Sample and Buffer Preparation for SAXS.

Adv Exp Med Biol 1009:11-30. doi: 10.1007/978-981-10-6038-0_2
Europe PMC | doi


Jeffries CM, Graewert MA, Blanchet CE, Langley DB, Whitten AE, Svergun DI. (2016)

Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments.

Nat Protoc 11(11):2122-2153. doi: 10.1038/nprot.2016.113
Europe PMC | doi

Plath F, Ringler P, Graff-Meyer A, Stahlberg H, Lauer ME, Rufer AC, Graewert MA, Svergun D, Gellermann G, Finkler C, Stracke JO, Koulov A, Schnaible V. (2016)

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.

MAbs 8(5):928-40. doi: 10.1080/19420862.2016.1168960
Europe PMC | doi

Schwemmer F, Blanchet CE, Spilotros A, Kosse D, Zehnle S, Mertens HD, Graewert MA, Rössle M, Paust N, Svergun DI, von Stetten F, Zengerle R, Mark D. (2016)

LabDisk for SAXS: a centrifugal microfluidic sample preparation platform for small-angle X-ray scattering.

Lab Chip 16(7):1161-1170. doi: 10.1039/c5lc01580d
Europe PMC | doi

Sousa BL, Silva-Filho JC, Kumar P, Graewert MA, Pereira RI, Cunha RM, Nascimento KS, Bezerra GA, Delatorre P, Djinovic-Carugo K, Nagano CS, Gruber K, Cavada BS. (2016)

Structural characterization of a Vatairea macrocarpa lectin in complex with a tumor-associated antigen: a new tool for cancer research.

Int. J. Biochem. Cell Biol. 72:27-39. doi: 10.1016/j.biocel.2015.12.016
Europe PMC | doi


Chen X, Hnida K, Graewert MA, Andersen JT, Iversen R, Tuukkanen A, Svergun D, Sollid LM. (2015)

Structural basis for antigen recognition by transglutaminase 2-specific autoantibodies in celiac disease.

J. Biol. Chem. doi: 10.1074/jbc.M115.669895
Europe PMC | doi

Graewert MA, Franke D, Jeffries CM, Blanchet CE, Ruskule D, Kuhle K, Flieger A, Schäfer B, Tartsch B, Meijers R, Svergun DI. (2015)

Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions.

Sci Rep 5 doi: 10.1038/srep10734
Europe PMC | doi

Blanchet CE, Spilotros A, Schwemmer F, Graewert MA, Kikhney A, Jeffries CM, Franke D, Mark D, Zengerle R, Cipriani F, Fiedler S, Roessle M, Svergun DI. (2015)

Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY).

J Appl Crystallogr 48(Pt 2):431-443. doi: 10.1107/s160057671500254x
Europe PMC | doi

Jeffries CM, Graewert MA, Svergun DI, Blanchet CE. (2015)

Limiting radiation damage for high-brilliance biological solution scattering: practical experience at the EMBL P12 beamline PETRAIII

J Synchrotron Radiat 22(Pt 2):273-279. doi: 10.1107/S1600577515000375
Europe PMC | doi


Berthelmann A, Lach J, Gräwert MA, Groll M, Eichler J. (2014)

Versatile C(3)-symmetric scaffolds and their use for covalent stabilization of the foldon trimer

Org. Biomol. Chem. 12(16):2606-2614. doi: 10.1039/c3ob42251h
Europe PMC | doi


Graewert MA, Svergun DI. (2013)

Impact and progress in small and wide angle X-ray scattering (SAXS and WAXS)

Curr. Opin. Struct. Biol. 23(5):748-754. doi: 10.1016/j.sbi.2013.06.007
Europe PMC | doi

Petoukhov MV, Billas IM, Takacs M, Graewert MA, Moras D, Svergun DI. (2013)

Reconstruction of quaternary structure from X-ray scattering by equilibrium mixtures of biological macromolecules

Biochemistry 52(39):6844-6855. doi: 10.1021/bi400731u
Europe PMC | doi

Müller R, Gräwert MA, Kern T, Madl T, Peschek J, Sattler M, Groll M, Buchner J. (2013)

High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation

Proc. Natl. Acad. Sci. U.S.A. 110(25):10183-10188. doi: 10.1073/pnas.1300547110
Europe PMC | doi


Schmid AB, Lagleder S, Gräwert MA, Röhl A, Hagn F, Wandinger SK, Cox MB, Demmer O, Richter K, Groll M, Kessler H, Buchner J. (2012)

The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop

EMBO J. 31(6):1506-1517. doi: 10.1038/emboj.2011.472
Europe PMC | doi

Gräwert MA, Groll M. (2012)

Exploiting nature's rich source of proteasome inhibitors as starting points in drug development

Chem. Commun. (Camb.) 48(10):1364-1378. doi: 10.1039/c1cc15273d
Europe PMC | doi


Gräwert MA, Gallastegui N, Stein M, Schmidt B, Kloetzel PM, Huber R, Groll M. (2011)

Elucidation of the α-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition

Angew. Chem. Int. Ed. Engl. 50(2):542-544. doi: 10.1002/anie.201005488
Europe PMC | doi


Poynor M, Eckert R, Nussberger S. (2008)

Dynamics of the preprotein translocation channel of the outer membrane of mitochondria.

Biophys J 95(3):1511-22. doi: 10.1529/biophysj.108.131003
Europe PMC | doi


Engelhardt H, Meins T, Poynor M, Adams V, Nussberger S, Welte W, Zeth K. (2007)

High-level expression, refolding and probing the natural fold of the human voltage-dependent anion channel isoforms I and II.

J Membr Biol 216(2-3):93-105. doi: 10.1007/s00232-007-9038-8
Europe PMC | doi

Arnold T, Poynor M, Nussberger S, Lupas AN, Linke D. (2007)

Gene duplication of the eight-stranded beta-barrel OmpX produces a functional pore: a scenario for the evolution of transmembrane beta-barrels.

J Mol Biol 366(4):1174-84. doi: 10.1016/j.jmb.2006.12.029
Europe PMC | doi