Development of high brilliance synchrotron X-ray scattering for advanced structural bio- and nanodiagnostics (BIOSCAT)

BMBF research grant
Starting date: 1 July 2012
Duration: 36 months
Total funding: € 258,755
Contract no: 05K12YE1
Coordinator: Dmitri Svergun

This German-Russian cooperation aims at development of novel technologies for structural studies of biological macromolecules in solution using synchrotron radiation and their applications to proteins and nanoparticles with medical relevance. The project is coordinated by the  EMBL Hamburg group of Dmitri Svergun and also involves Luebeck University Junior Research Group of Lars Redecke and researchers from the Kurchatov Institute, Shubnikov Institute of Crystallography (both Moscow), Moscow State University and the Joint Institute for Nuclear Research (Dubna).

Physical principles in the self-assembly of immature HIV-1 particles

Human Frontier Science Program research grant
Starting date: 1 July 2012
Duration: 36 months
Total funding: € 228,000
Contract no: RGP0017/2012
Coordinator: Bogdan Dragnea

This interdisciplinary institutional collaboration aims at understanding of the structural properties of HIV-1 assembly intermediates to be able to interfere with the stages of the virus life cycle. The project, coordinated by Bogdan Dragnea from Indiana University Bloomington, USA, involves, in addition to the EMBL Hamburg group of Dmitri Svergun, also groups led by Alan Rein of the National Cancer Institute in Frederick, MD (USA) and Paul Van der Schoot of the University of Twente in Netherlands.