Publications

Total: 454 publication(s)

2018

Esposito A, Ventura V, Petoukhov MV, Rai A, Svergun DI, Vanoni MA. (2018)

Human MICAL1: activation by the small GTPase Rab8 and small-angle X-ray scattering studies on the oligomerization state of MICAL1 and its complex with Rab8.

Protein Sci doi: 10.1002/pro.3512
Europe PMC | doi

Fuertes G, Banterle N, Ruff KM, Chowdhury A, Pappu RV, Svergun DI, Lemke EA. (2018)

Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water".

Science 361(6405) doi: 10.1126/science.aau8230
Europe PMC | doi

Martínez-Lumbreras S, Krysztofinska EM, Thapaliya A, Spilotros A, Matak-Vinkovic D, Salvadori E, Roboti P, Nyathi Y, Muench JH, Roessler MM, Svergun DI, High S, Isaacson RL. (2018)

Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control.

BMC Biol. 16(1) doi: 10.1186/s12915-018-0542-3
Europe PMC | doi

Schroer MA, Blanchet CE, Gruzinov AY, Gräwert MA, Brennich ME, Hajizadeh NR, Jeffries CM, Svergun DI. (2018)

Smaller capillaries improve the small-angle X-ray scattering signal and sample consumption for biomacromolecular solutions

J Synchrotron Radiat 25:1113-1122. doi: 10.1107/S1600577518007907
Europe PMC | doi

Blaschke U, Suwono B, Zafari S, Ebersberger I, Skiebe E, Jeffries CM, Svergun DI, Wilharm G. (2018)

Recombinant production of A1S_0222 from Acinetobacter baumannii ATCC 17978 and confirmation of its DNA-(adenine N6)-methyltransferase activity.

Protein Expr. Purif. 151 doi: 10.1016/j.pep.2018.06.009
Europe PMC | doi

Franke D, Jeffries CM, Svergun DI. (2018)

Machine Learning Methods for X-Ray Scattering Data Analysis from Biomacromolecular Solutions.

Biophys. J. 114(11):2485-2492. doi: 10.1016/j.bpj.2018.04.018
Europe PMC | doi

Konarev PV, Svergun DI. (2018)

Direct shape determination of intermediates in evolving macromolecular solutions from small-angle scattering data.

IUCrJ 5(Pt 4):402-409. doi: 10.1107/S2052252518005900
Europe PMC | doi

Josts I, Nitsche J, Maric S, Mertens HD, Moulin M, Haertlein M, Prevost S, Svergun DI, Busch S, Forsyth VT, Tidow H. (2018)

Conformational States of ABC Transporter MsbA in a Lipid Environment Investigated by Small-Angle Scattering Using Stealth Carrier Nanodiscs.

Structure 26(8) doi: 10.1016/j.str.2018.05.007
Europe PMC | doi

Marcianò G, Da Vela S, Tria G, Svergun DI, Byron O, Huang DT. (2018)

Structure specific recognition protein-1 (SSRP1) is an elongated homodimer that binds histones.

J Biol Chem doi: 10.1074/jbc.RA117.000994
Europe PMC | doi

Hajizadeh NR, Franke D, Jeffries CM, Svergun DI.. (2018)

Consensus Bayesian assessment of protein molecular mass from solution X-ray scattering data

Sci Rep 8(1):7204. doi: 10.1038/s41598-018-25355-2
Europe PMC | doi

Hajizadeh NR, Franke D, Svergun DI. (2018)

Integrated beamline control and data acquisition for small-angle X-ray scattering at the P12 BioSAXS beamline at PETRAIII storage ring DESY.

J Synchrotron Radiat 25(Pt 3):906-914. doi: 10.1107/S1600577518005398
Europe PMC | doi

Chen PC, Masiewicz P, Rybin V, Svergun D, Hennig J. (2018)

A General Small-Angle X-ray Scattering-Based Screening Protocol Validated for Protein-RNA Interactions.

ACS Comb Sci 20(4) doi: 10.1021/acscombsci.8b00007
Europe PMC | doi

Cordeiro M, Otrelo-Cardoso AR, Svergun DI, Konarev PV, Lima JC, Santos-Silva T, Baptista PV. (2018)

Optical and Structural Characterization of a Chronic Myeloid Leukemia DNA Biosensor.

ACS Chem Biol 13(5) doi: 10.1021/acschembio.8b00029
Europe PMC | doi

de Moura TR, Mozaffari-Jovin S, Szabó CZK, Schmitzová J, Dybkov O, Cretu C, Kachala M, Svergun D, Urlaub H, Lührmann R, Pena V. (2018)

Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.

Mol Cell 69(6):979-992.e6. doi: 10.1016/j.molcel.2018.02.022
Europe PMC | doi

Nyíri K, Mertens HDT, Tihanyi B, Nagy GN, Kőhegyi B, Matejka J, Harris MJ, Szabó JE, Papp-Kádár V, Németh-Pongrácz V, Ozohanics O, Vékey K, Svergun DI, Borysik AJ, Vértessy BG. (2018)

Structural model of human dUTPase in complex with a novel proteinaceous inhibitor.

Sci Rep 8(1) doi: 10.1038/s41598-018-22145-8
Europe PMC | doi

Slonimskiy YB, Maksimov EG, Lukashev EP, Moldenhauer M, Jeffries CM, Svergun DI, Friedrich T, Sluchanko NN.. (2018)

Functional interaction of low-homology FRPs from different cyanobacteria with Synechocystis OCP

Biochimica et biophysica acta - Bioenergetics 1859(5):382-393. doi: 10.1016/j.bbabio.2018.03.001
Europe PMC | doi

Falke S, Dierks K, Blanchet C, Graewert M, Cipriani F, Meijers R, Svergun D, Betzel C. (2018)

Multi-channel in situ dynamic light scattering instrumentation enhancing biological small-angle X-ray scattering experiments at the PETRA III beamline P12.

J Synchrotron Radiat 25(Pt 2):361-372. doi: 10.1107/S1600577517017568
Europe PMC | doi

Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang JH, Meijers R. (2018)

Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.

Neuron 97(6) doi: 10.1016/j.neuron.2018.02.010
Europe PMC | doi

Bunney TD, Inglis AJ, Sanfelice D, Farrell B, Kerr CJ, Thompson GS, Masson GR, Thiyagarajan N, Svergun DI, Williams RL, Breeze AL, Katan M. (2018)

Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System.

Structure 26(3) doi: 10.1016/j.str.2018.01.016
Europe PMC | doi

Flayhan A, Mertens HDT, Ural-Blimke Y, Martinez Molledo M, Svergun DI, Löw C. (2018)

Saposin Lipid Nanoparticles: A Highly Versatile and Modular Tool for Membrane Protein Research.

Structure 26(2):345-355.e5. doi: 10.1016/j.str.2018.01.007
Europe PMC | doi

Adinolfi S, Puglisi R, Crack JC, Iannuzzi C, Dal Piaz F, Konarev PV, Svergun DI, Martin S, Le Brun NE, Pastore A. (2018)

The Molecular Bases of the Dual Regulation of Bacterial Iron Sulfur Cluster Biogenesis by CyaY and IscX.

Front Mol Biosci 4:97. doi: 10.3389/fmolb.2017.00097
Europe PMC | doi

Aronsson A, Güler F, Petoukhov MV, Crennell SJ, Svergun DI, Linares-Pastén JA, Karlsson EN. (2018)

Structural insights of RmXyn10A - A prebiotic-producing GH10 xylanase with a non-conserved aglycone binding region.

Biochim. Biophys. Acta 1866(2) doi: 10.1016/j.bbapap.2017.11.006
Europe PMC | doi

Kordyukova LV, Shtykova EV, Baratova LA, Svergun DI, Batishchev OV. (2018)

Matrix proteins of enveloped viruses: a case study of Influenza A virus M1 protein.

J. Biomol. Struct. Dyn. 1-46. doi: 10.1080/07391102.2018.1436089
Europe PMC | doi

Zhang X, Niebuur BJ, Chytil P, Etrych T, Filippov SK, Kikhney A, Wieland DCF, Svergun DI, Papadakis CM. (2018)

Macromolecular pHPMA-Based Nanoparticles with Cholesterol for Solid Tumor Targeting: Behavior in HSA Protein Environment.

Biomacromolecules 19(2) doi: 10.1021/acs.biomac.7b01579
Europe PMC | doi

Garcia-Alai MM, Heidemann J, Skruzny M, Gieras A, Mertens HDT, Svergun DI, Kaksonen M, Uetrecht C, Meijers R. (2018)

Epsin and Sla2 form assemblies through phospholipid interfaces.

Nat Commun 9(1) doi: 10.1038/s41467-017-02443-x
Europe PMC | doi

Pflüger T, Hernández CF, Lewe P, Frank F, Mertens H, Svergun D, Baumstark MW, Lunin VY, Jetten MSM, Andrade SLA. (2018)

Signaling ammonium across membranes through an ammonium sensor histidine kinase.

Nat Commun 9(1) doi: 10.1038/s41467-017-02637-3
Europe PMC | doi


2017

Panjkovich A, Svergun DI. (2017)

CHROMIXS: automatic and interactive analysis of chromatography-coupled small angle X-ray scattering data.

Bioinformatics 34(11) doi: 10.1093/bioinformatics/btx846
Europe PMC | doi

Reckel S, Gehin C, Tardivon D, Georgeon S, Kükenshöner T, Löhr F, Koide A, Buchner L, Panjkovich A, Reynaud A, Pinho S, Gerig B, Svergun D, Pojer F, Güntert P, Dötsch V, Koide S, Gavin AC, Hantschel O. (2017)

Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.

Nat Commun 8(1) doi: 10.1038/s41467-017-02313-6
Europe PMC | doi

Shtykova EV, Dadinova LA, Fedorova NV, Golanikov AE, Bogacheva EN, Ksenofontov AL, Baratova LA, Shilova LA, Tashkin VY, Galimzyanov TR, Jeffries CM, Svergun DI, Batishchev OV. (2017)

Influenza virus Matrix Protein M1 preserves its conformation with pH, changing multimerization state at the priming stage due to electrostatics.

Sci Rep 7(1) doi: 10.1038/s41598-017-16986-y
Europe PMC | doi

Gdovinová V, Schroer MA, Tomašovičová N, Appel I, Behrens S, Majorošová J, Kováč J, Svergun DI, Kopčanský P. (2017)

Structuralization of magnetic nanoparticles in 5CB liquid crystals.

Soft Matter 13(43) doi: 10.1039/c7sm01234a
Europe PMC | doi

Trewhella J, Duff AP, Durand D, Gabel F, Guss JM, Hendrickson WA, Hura GL, Jacques DA, Kirby NM, Kwan AH, Pérez J, Pollack L, Ryan TM, Sali A, Schneidman-Duhovny D, Schwede T, Svergun DI, Sugiyama M, Tainer JA, Vachette P, Westbrook J, Whitten AE. (2017)

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.

Acta Crystallogr D Struct Biol 73(Pt 9):710-728. doi: 10.1107/S2059798317011597
Europe PMC | doi

Filippov SK, Verbraeken B, Konarev PV, Svergun DI, Angelov B, Vishnevetskaya NS, Papadakis CM, Rogers S, Radulescu A, Courtin T, Martins JC, Starovoytova L, Hruby M, Stepanek P, Kravchenko VS, Potemkin II, Hoogenboom R. (2017)

Block and Gradient Copoly(2-oxazoline) Micelles: Strikingly Different on the Inside.

J Phys Chem Lett 8(16):3800-3804. doi: 10.1021/acs.jpclett.7b01588
Europe PMC | doi

Mertens HDT, Svergun DI. (2017)

Combining NMR and small angle X-ray scattering for the study of biomolecular structure and dynamics.

Arch Biochem Biophys 628 doi: 10.1016/j.abb.2017.05.005
Europe PMC | doi

Tuukkanen AT, Spilotros A, Svergun DI. (2017)

Progress in small-angle scattering from biological solutions at high-brilliance synchrotrons.

IUCrJ 4(Pt 5):518-528. doi: 10.1107/S2052252517008740
Europe PMC | doi

Fuertes G, Banterle N, Ruff KM, Chowdhury A, Mercadante D, Koehler C, Kachala M, Estrada Girona G, Milles S, Mishra A, Onck PR, Gräter F, Esteban-Martín S, Pappu RV, Svergun DI, Lemke EA. (2017)

Decoupling of size and shape fluctuations in heteropolymeric sequences reconciles discrepancies in SAXS vs. FRET measurements.

Proc Natl Acad Sci U S A 114(31):E6342-E6351. doi: 10.1073/pnas.1704692114
Europe PMC | doi

Otrelo-Cardoso AR, Nair RR, Correia MAS, Cordeiro RSC, Panjkovich A, Svergun DI, Santos-Silva T, Rivas MG. (2017)

Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20.

Sci Rep 7(1) doi: 10.1038/s41598-017-06133-y
Europe PMC | doi

Holdbrook DA, Burmann BM, Huber RG, Petoukhov MV, Svergun DI, Hiller S, Bond PJ. (2017)

A Spring-Loaded Mechanism Governs the Clamp-like Dynamics of the Skp Chaperone.

Structure 25(7):1079-1088.e3. doi: 10.1016/j.str.2017.05.018
Europe PMC | doi

Franke D, Petoukhov MV, Konarev PV, Panjkovich A, Tuukkanen A, Mertens HDT, Kikhney AG, Hajizadeh NR, Franklin JM, Jeffries CM, Svergun DI. (2017)

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

J Appl Crystallogr 50(4):1212-1225. doi: 10.1107/S1600576717007786
Europe PMC | doi

Beckham KS, Ciccarelli L, Bunduc CM, Mertens HD, Ummels R, Lugmayr W, Mayr J, Rettel M, Savitski MM, Svergun DI, Bitter W, Wilmanns M, Marlovits TC, Parret AH, Houben EN. (2017)

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis.

Nat Microbiol 2(6):17047. doi: 10.1038/nmicrobiol.2017.47
Europe PMC | doi

Sundaramoorthy R, Hughes AL, Singh V, Wiechens N, Ryan DP, El-Mkami H, Petoukhov M, Svergun DI, Treutlein B, Quack S, Fischer M, Michaelis J, Böttcher B, Norman DG, Owen-Hughes T. (2017)

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes.

Elife 6:1-28. doi: 10.7554/elife.22510
Europe PMC | doi

Sviridova E, Rezacova P, Bondar A, Veverka V, Novak P, Schenk G, Svergun DI, Kuta Smatanova I, Bumba L. (2017)

Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis.

Sci Rep 7(40408):1-14. doi: 10.1038/srep40408
Europe PMC | doi

Mauricio RP, Jeffries CM, Svergun DI, Deane JE. (2017)

The Shigella Virulence Factor IcsA Relieves N-WASP Autoinhibition by Displacing the Verprolin Homology/Cofilin/Acidic (VCA) Domain.

J. Biol. Chem. 292(1):134-145. doi: 10.1074/jbc.m116.758003
Europe PMC | doi

Liu J, Falke S, Drobot B, Oberthuer D, Kikhney A, Guenther T, Fahmy K, Svergun D, Betzel C, Raff J. (2017)

Analysis of self-assembly of S-layer protein slp-B53 from Lysinibacillus sphaericus.

Eur. Biophys. J. 46(1):77-89. doi: 10.1007/s00249-016-1139-9
Europe PMC | doi


2016

Pirone L, Smaldone G, Esposito C, Balasco N, Petoukhov MV, Spilotros A, Svergun DI, Di Gaetano S, Vitagliano L, Pedone EM. (2016)

Proteins involved in sleep homeostasis: Biophysical characterization of INC and its partners.

Biochimie 131:106-114. doi: 10.1016/j.biochi.2016.09.013
Europe PMC | doi

Waring M., Chen H., Rabow A., Walker G., Bobby R., Boiko S., Bradbury R., Callis R., Clark E., Dale I., Daniels D., Dulak A., Flavell L., Holdgate G., Jowitt T., Kikhney A., McAlister M., Méndez J., Ogg D., Patel J., Petteruti P., Robb G., Robers M., Saif S., Stratton N., Svergun D., Wang W., Whittaker D., Wilson D., Yao Y.. (2016)

Potent and selective bivalent inhibitors of BET bromodomains

Nat. Chem. Biol. 12(12):1097-1104. doi: 10.1038/nchembio.2210
Europe PMC | doi

Jeffries CM, Graewert MA, Blanchet CE, Langley DB, Whitten AE, Svergun DI. (2016)

Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments.

Nat Protoc 11(11):2122-2153. doi: 10.1038/nprot.2016.113
Europe PMC | doi

Tuukkanen A., Kleywegt G., Svergun D.. (2016)

Resolution of ab initio shapes determined from small-angle scattering

IUCrJ 3(Pt 6):440-447. doi: 10.1107/S2052252516016018
Europe PMC | doi

Saxena P, He L, Malyutin A, Datta SA, Rein A, Bond KM, Jarrold MF, Spilotros A, Svergun D, Douglas T, Dragnea B. (2016)

Virus Matryoshka: A Bacteriophage Particle-Guided Molecular Assembly Approach to a Monodisperse Model of the Immature Human Immunodeficiency Virus.

Small 12(42) doi: 10.1002/smll.201601712
Europe PMC | doi

Buetow L, Tria G, Ahmed SF, Hock A, Dou H, Sibbet GJ, Svergun DI, Huang DT. (2016)

Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.

BMC Biol. 14 doi: 10.1186/s12915-016-0298-6
Europe PMC | doi

Schulte T, Mikaelsson C, Beaussart A, Kikhney A, Deshmukh M, Wolniak S, Pathak A, Ebel C, Löfling J, Fogolari F, Henriques-Normark B, Dufrêne YF, Svergun D, Nygren PÅ, Achour A. (2016)

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation.

Sci Rep 6 doi: 10.1038/srep32371
Europe PMC | doi

Mathiasen L, Valentini E, Boivin S, Cattaneo A, Blasi F, Svergun DI, Bruckmann C. (2016)

The flexibility of a homeodomain transcription factor heterodimer and its allosteric regulation by DNA binding.

FEBS J. 283(16) doi: 10.1111/febs.13801
Europe PMC | doi

Szameit K, Berg K, Kruspe S, Valentini E, Magbanua E, Kwiatkowski M, Chauvot de Beauchêne I, Krichel B, Schamoni K, Uetrecht C, Svergun DI, Schlüter H, Zacharias M, Hahn U. (2016)

Structure and target interaction of a G-quadruplex RNA-aptamer.

RNA Biol 13(10):973-987. doi: 10.1080/15476286.2016.1212151
Europe PMC | doi

Yang X, Wang S, King TL, Kerr CJ, Blanchet C, Svergun D, Pal R, Beeby A, Vadivelu J, Brown KA, Jones RA, Zhang L, Huang S. (2016)

Anisotropic lanthanide-based nano-clusters for imaging applications.

Faraday Discuss. 191 doi: 10.1039/c6fd00018e
Europe PMC | doi

Valencia-Sánchez MI, Rodríguez-Hernández A, Ferreira R, Santamaría-Suárez HA, Arciniega M, Dock-Bregeon AC, Moras D, Beinsteiner B, Mertens H, Svergun D, Brieba LG, Grøtli M, Torres-Larios A. (2016)

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases.

J. Biol. Chem. 291(28):14430-14446. doi: 10.1074/jbc.m116.730382
Europe PMC | doi

Panjkovich A, Svergun DI. (2016)

SASpy: a PyMOL plugin for manipulation and refinement of hybrid models against small angle X-ray scattering data.

Bioinformatics 32(13):2062-2064. doi: 10.1093/bioinformatics/btw071
Europe PMC | doi

Plath F, Ringler P, Graff-Meyer A, Stahlberg H, Lauer ME, Rufer AC, Graewert MA, Svergun D, Gellermann G, Finkler C, Stracke JO, Koulov A, Schnaible V. (2016)

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.

MAbs 8(5):928-40. doi: 10.1080/19420862.2016.1168960
Europe PMC | doi

Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney AG, Koch-Nolte F, Buck F, Perbandt M, Betzel C, Svergun DI, Hentschke M, Aepfelbacher M. (2016)

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells.

PLoS Pathog. 12(6):e1005660. doi: 10.1371/journal.ppat.1005660
Europe PMC | doi

Simon B, Huart A, Temmerman K, Vahokoski J, Mertens H, Komadina D, Hoffmann J, Yumerefendi H, Svergun D, Kursula P, Schultz C, McCarthy A, Hart D, Wilmanns M. (2016)

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

Structure 24(6):851-861. doi: 10.1016/j.str.2016.03.020
Europe PMC | doi

Dadinova LA, Shtykova EV, Konarev PV, Rodina EV, Snalina NE, Vorobyeva NN, Kurilova SA, Nazarova TI, Jeffries CM, Svergun DI.. (2016)

X-Ray Solution Scattering Study of Four Escherichia coli Enzymes Involved in Stationary-Phase Metabolism

PLoS ONE 11(5):e0156105. doi: 10.1371/journal.pone.0156105
Europe PMC | doi

Konarev PV, Petoukhov MV, Svergun DI. (2016)

Rapid automated superposition of shapes and macromolecular models using spherical harmonics.

J Appl Crystallogr 49(Pt 3):953-960. doi: 10.1107/S1600576716005793
Europe PMC | doi

Bumba L, Masin J, Macek P, Wald T, Motlova L, Bibova I, Klimova N, Bednarova L, Veverka V, Kachala M, Svergun DI, Barinka C, Sebo P. (2016)

Calcium-Driven Folding of RTX Domain β-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts.

Mol. Cell 62(1):47-62. doi: 10.1016/j.molcel.2016.03.018
Europe PMC | doi

Schwemmer F, Blanchet CE, Spilotros A, Kosse D, Zehnle S, Mertens HD, Graewert MA, Rössle M, Paust N, Svergun DI, von Stetten F, Zengerle R, Mark D. (2016)

LabDisk for SAXS: a centrifugal microfluidic sample preparation platform for small-angle X-ray scattering.

Lab Chip 16(7):1161-1170. doi: 10.1039/c5lc01580d
Europe PMC | doi

Drebes J, Künz M, Windshügel B, Kikhney AG, Müller IB, Eberle RJ, Oberthür D, Cang H, Svergun DI, Perbandt M, Betzel C, Wrenger C. (2016)

Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.

Sci Rep 6 doi: 10.1038/srep22871
Europe PMC | doi

Dunne M, Leicht S, Krichel B, Mertens HD, Thompson A, Krijgsveld J, Svergun DI, Gómez-Torres N, Garde S, Uetrecht C, Narbad A, Mayer MJ, Meijers R. (2016)

Crystal structure of the CTP1L endolysin reveals how its activity is regulated by a secondary translation product.

J. Biol. Chem. 291(10):4882-4893. doi: 10.1074/jbc.M115.671172
Europe PMC | doi

Belorusova AY, Osz J, Petoukhov MV, Peluso-Iltis C, Kieffer B, Svergun DI, Rochel N. (2016)

Solution Behavior of the Intrinsically Disordered N-Terminal Domain of Retinoid X Receptor α in the Context of the Full-Length Protein.

Biochemistry 55(12):1741-1748. doi: 10.1021/acs.biochem.5b01122
Europe PMC | doi

Panjkovich A, Svergun DI. (2016)

Deciphering conformational transitions of proteins by small angle X-ray scattering and normal mode analysis.

Phys Chem Chem Phys 18(8):5707-5719. doi: 10.1039/c5cp04540a
Europe PMC | doi

Boer DR, Ruiz-Masó JA, Rueda M, Petoukhov MV, Machón C, Svergun DI, Orozco M, Del Solar G, Coll M. (2016)

Conformational plasticity of RepB, the replication initiator protein of promiscuous streptococcal plasmid pMV158.

Sci Rep 6 doi: 10.1038/srep20915
Europe PMC | doi

Kachala M, Westbrook J, Svergun D. (2016)

Extension of the sasCIF format and its applications for data processing and deposition.

J Appl Crystallogr 49(Pt 1):302-310. doi: 10.1107/S1600576715024942
Europe PMC | doi

Kikhney AG, Panjkovich A, Sokolova AV, Svergun DI. (2016)

DARA: a web server for rapid search of structural neighbours using solution small angle X-ray scattering data.

Bioinformatics 32(4):616-618. doi: 10.1093/bioinformatics/btv611
Europe PMC | doi

Gráczer É, Szimler T, Garamszegi A, Konarev PV, Lábas A, Oláh J, Palló A, Svergun DI, Merli A, Závodszky P, Weiss MS, Vas M. (2016)

Dual Role of the Active Site Residues of Thermus thermophilus 3-Isopropylmalate Dehydrogenase: Chemical Catalysis and Domain Closure.

Biochemistry 55(3):560-574. doi: 10.1021/acs.biochem.5b00839
Europe PMC | doi


2015

Albesa-Jové D, Comino N, Tersa M, Mohorko E, Urresti S, Dainese E, Chiarelli LR, Pasca MR, Manganelli R, Makarov V, Riccardi G, Svergun DI, Glockshuber R, Guerin ME. (2015)

The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.

J. Biol. Chem. 290(52):31077-31089. doi: 10.1074/jbc.M115.677039
Europe PMC | doi

Ponnusamy R, Petoukhov MV, Correia B, Custodio TF, Juillard F, Tan M, Pires de Miranda M, Carrondo MA, Simas JP, Kaye KM, Svergun DI, McVey CE.. (2015)

KSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA.

Nucleic Acids Res. 43(20) doi: 10.1093/nar/gkv987
Europe PMC | doi

Kachala M, Valentini E, Svergun DI. (2015)

Application of SAXS for the Structural Characterization of IDPs.

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Fadouloglou VE, Lin HV, Tria G, Hernández H, Robinson CV, Svergun DI, Luisi BF. (2015)

Maturation of 6S regulatory RNA to a highly elongated structure.

FEBS J 282(23) doi: 10.1111/febs.13516
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Kikhney AG, Svergun DI. (2015)

A practical guide to small angle X-ray scattering (SAXS) of flexible and intrinsically disordered proteins.

FEBS Lett 589(19 Pt A):2570-2577. doi: 10.1016/j.febslet.2015.08.027
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Mittelberger F, Meyer C, Waetzig GH, Zacharias M, Valentini E, Svergun DI, Berg K, Lorenzen I, Grötzinger J, Rose-John S, Hahn U. (2015)

RAID3 - An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity.

RNA Biol 12(9):1043-1053. doi: 10.1080/15476286.2015.1079681
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Škerlová J, Král V, Kachala M, Fábry M, Bumba L, Svergun DI, Tošner Z, Veverka V, Řezáčová P. (2015)

Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85.

J. Struct. Biol. 191(2):214-223. doi: 10.1016/j.jsb.2015.06.005
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Chen X, Hnida K, Graewert MA, Andersen JT, Iversen R, Tuukkanen A, Svergun D, Sollid LM. (2015)

Structural basis for antigen recognition by transglutaminase 2-specific autoantibodies in celiac disease.

J. Biol. Chem. 290(35) doi: 10.1074/jbc.M115.669895
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Mercadante D, Milles S, Fuertes G, Svergun DI, Lemke EA, Gräter F. (2015)

Kirkwood-Buff Approach Rescues Overcollapse of a Disordered Protein in Canonical Protein Force Fields

J Phys Chem B 119(25):7975-7984. doi: 10.1021/acs.jpcb.5b03440
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Sali A, Berman HM, Schwede T, Trewhella J, Kleywegt G, Burley SK, Markley J, Nakamura H, Adams P, Bonvin AM, Chiu W, Peraro MD, Di Maio F, Ferrin TE, Grünewald K, Gutmanas A, Henderson R, Hummer G, Iwasaki K, Johnson G, Lawson CL, Meiler J, Marti-Renom MA, Montelione GT, Nilges M, Nussinov R, Patwardhan A, Rappsilber J, Read RJ, Saibil H, Schröder GF, Schwieters CD, Seidel CA, Svergun D, Topf M, Ulrich EL, Velankar S, Westbrook JD. (2015)

Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop.

Structure 23(7) doi: 10.1016/j.str.2015.05.013
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Malyutin AG, Cheng H, Sanchez-Felix OR, Carlson K, Stein BD, Konarev PV, Svergun DI, Dragnea B, Bronstein LM. (2015)

Coat Protein-Dependent Behavior of Poly(ethylene glycol) Tails in Iron Oxide Core Virus-like Nanoparticles

ACS Appl. Mater. Interfaces 7(22):12089-12098. doi: 10.1021/acsami.5b02278
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Graewert MA, Franke D, Jeffries CM, Blanchet CE, Ruskule D, Kuhle K, Flieger A, Schäfer B, Tartsch B, Meijers R, Svergun DI. (2015)

Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions.

Sci Rep 5 doi: 10.1038/srep10734
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Gruszka DT, Whelan F, Farrance OE, Fung HK, Paci E, Jeffries CM, Svergun DI, Baldock C, Baumann CG, Brockwell DJ, Potts JR, Clarke J. (2015)

Cooperative folding of intrinsically disordered domains drives assembly of a strong elongated protein.

Nat Commun 6 doi: 10.1038/ncomms8271
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Petoukhov MV, Svergun DI. (2015)

Ambiguity assessment of small-angle scattering curves from monodisperse systems.

Acta Crystallogr. D Biol. Crystallogr. 71(Pt 5):1051-1058. doi: 10.1107/s1399004715002576
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Jiménez-García B, Pons C, Svergun DI, Bernadó P, Fernández-Recio J. (2015)

pyDockSAXS: protein-protein complex structure by SAXS and computational docking.

Nucleic Acids Res. 43(W1):W356-W361. doi: 10.1093/nar/gkv368
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Konarev PV, Svergun DI. (2015)

A posteriori determination of the useful data range for small-angle scattering experiments on dilute monodisperse systems.

IUCrJ 2(Pt 3):352-360. doi: 10.1107/s2052252515005163
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Franke D, Jeffries CM, Svergun DI. (2015)

Correlation Map, a goodness-of-fit test for one-dimensional X-ray scattering spectra.

Nat Methods 12(5):419-422. doi: 10.1038/nmeth.3358
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Langkilde AE, Morris KL, Serpell LC, Svergun DI, Vestergaard B. (2015)

The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy

Acta Crystallogr. Sect. D-Biol. Crystallogr. 71:882-895. doi: 10.1107/S1399004715001674
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Thomsen M, Tuukkanen A, Dickerhoff J, Palm GJ, Kratzat H, Svergun DI, Weisz K, Bornscheuer UT, Hinrichs W. (2015)

Structure and catalytic mechanism of the evolutionarily unique bacterial chalcone isomerase

Acta Crystallogr. Sect. D-Biol. Crystallogr. 71:907-917. doi: 10.1107/S1399004715001935
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Blanchet CE, Spilotros A, Schwemmer F, Graewert MA, Kikhney A, Jeffries CM, Franke D, Mark D, Zengerle R, Cipriani F, Fiedler S, Roessle M, Svergun DI. (2015)

Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY).

J Appl Crystallogr 48(Pt 2):431-443. doi: 10.1107/s160057671500254x
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Song JG, Kostan J, Drepper F, Knapp B, de Almeida Ribeiro E Jr, Konarev PV, Grishkovskaya I, Wiche G, Gregor M, Svergun DI, Warscheid B, Djinović-Carugo K. (2015)

Structural Insights into Ca(2+)-Calmodulin Regulation of Plectin 1a-Integrin β4 Interaction in Hemidesmosomes.

Structure 23(3):558-570. doi: 10.1016/j.str.2015.01.011
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Blanchet CE, Hermes C, Svergun DI, Fiedler S. (2015)

A small and robust active beamstop for scattering experiments on high-brilliance undulator beamlines.

J Synchrotron Radiat 22(Pt 2):461-464. doi: 10.1107/s160057751402829x
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Tria G, Mertens HD, Kachala M, Svergun DI. (2015)

Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering.

IUCrJ 2(Pt 2):207-217. doi: 10.1107/s205225251500202x
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Jeffries CM, Graewert MA, Svergun DI, Blanchet CE. (2015)

Limiting radiation damage for high-brilliance biological solution scattering: practical experience at the EMBL P12 beamline PETRAIII

J Synchrotron Radiat 22(Pt 2):273-279. doi: 10.1107/S1600577515000375
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Covaceuszach S, Konarev PV, Cassetta A, Paoletti F, Svergun DI, Lamba D, Cattaneo A. (2015)

The Conundrum of the High-Affinity NGF Binding Site Formation Unveiled?

Biophys. J. 108(3):687-697. doi: 10.1016/j.bpj.2014.11.3485
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Valentini E, Kikhney AG, Previtali G, Jeffries CM, Svergun DI. (2015)

SASBDB, a repository for biological small-angle scattering data

Nucleic Acids Res. 43(D1):D357-D363. doi: 10.1093/nar/gku1047
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Gráczer É, Palló A, Oláh J, Szimler T, Konarev PV, Svergun DI, Merli A, Závodszky P, Weiss MS, Vas M. (2015)

Glutamate 270 plays an essential role in K(+)-activation and domain closure of Thermus thermophilus isopropylmalate dehydrogenase.

FEBS Lett. 589(2) doi: 10.1016/j.febslet.2014.12.005
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Malyutin AG, Easterday R, Lozovyy Y, Spilotros A, Cheng H, Sanchez-Felix OR, Stein BD, Morgan DG, Svergun DI, Dragnea B, Bronstein LM. (2015)

Viruslike Nano Particles with Maghemite Cores Allow for Enhanced MRI Contrast Agents

Chem. Mat. 27(1):327-335. doi: 10.1021/cm504029j
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Tallant C, Valentini E, Fedorov O, Overvoorde L, Ferguson FM, Filippakopoulos P, Svergun DI, Knapp S, Ciulli A. (2015)

Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC.

Structure 23(1):80-92. doi: 10.1016/j.str.2014.10.017
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De Maria Antolinos A, Pernot P, Brennich ME, Kieffer J, Bowler MW, Delageniere S, Ohlsson S, Malbet Monaco S, Ashton A, Franke D, Svergun D, McSweeney S, Gordon E, Round A. (2015)

ISPyB for BioSAXS, the gateway to user autonomy in solution scattering experiments.

Acta Crystallogr. D Biol. Crystallogr. 71(Pt 1):76-85. doi: 10.1107/s1399004714019609
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