ViCi is an innovative software for ligand-based drug design available free of charge to
academic researchers via this webserver. ViCi uses a combination of mathematical descriptors
of molecular size, shape and topology to describe small molecule structures. Following input
of a template molecule, typically that of a known ligand in its bound conformation in a
particular protein, the software will rapidly screen a database (currently 8 million compounds)
and extract those predicted to have similar shape and electrostatic compositions and therefore
to be possible ligands for the same protein. Results are typically obtained in a matter of
hours and are returned to the user ranked by probability of binding.
We thank for public support and funding.
Access to the ViCi webserver is via a token-based system and is available only to bona fide
academic researchers who have indicated their agreement with the terms and conditions of the
license, which can be read here. If
you are an academic user and do not have tokens for use of the software, please complete the
section below with your name and e-mail address and you will receive a set of tokens by return
e-mail. If you have already been supplied with valid tokens, please indicate so by clicking
on the 'I already have a valid token' button below. If you intend to make use of the server
for commercial purposes or otherwise do not agree with the terms of the license, please
contact Victor Lamzin
for making special arrangements.