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| Jill Trewhella - Scattering of Neutrons (basics) | |
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Jill Trewhella
University of Sydney, Australia
The scattering of neutrons and X-rays by macromolecules in solution gives rise to small-angle scattering patterns that can provide the same (or at least very similar) information about the size and shape of the scattering molecule. There are common underlying principals and methods for extracting this information. Because neutrons are scattered by the nuclei in the sample, different isotopes of the same elements can have very different scattering properties.
These kinds of differences are not observed for X-rays as they are scattered by electrons and hence X-ray scattering power increases monotonically with the number of electrons.
This presentation will describe the basics of neutron scattering, emphasizing the differences from X-ray scattering and how these differences can be capitalized on to study the structures of the components within macromolecular complexes and assemblies. Contrast variation and solvent matching experiments will be described as well as the methods for analyzing these data sets along with the limitations and strengths of different approaches.
Date/time: Monday, 23 October, 11:00
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