| Provisional programme: |
| Monday, August 27, 2007 |
| 08:30-09:30 |
|
| 09:30-13:00 |
Session 1: Replication strategies of (+) strand ssRNA viruses
Chairs: Eric Snijder, Jacques Rohayem
| |
| 09:30-09:40 |
|
| 09:40-10:20 |
| Raul Andino - The structure of the quasispecies and the ability of viruses to adapt to changing environments |
|
| 10:20-11:00 |
| Ralf Bartenschlager - New insights into hepatitis C virus replication and assembly: defining new targets for antiviral intervention |
|
| 11:00-11:20 | Coffee break |
| 11:20-12:00 |
| Bruno Canard - The flavivirus RNA capping and RNA synthesis machinery: structural and mechanistic insights |
|
| 12:00-12:40 |
| Jacques Rohayem - Caliciviruses: replication strategy and evolution |
|
| 12:40-13:00 |
| Andrew Davidson - Structure function analysis of the dengue virus NS5 protein |
|
| 13:00-14:30 | Lunch break |
| 14:30-17:50 |
Session 1 (cont): Replication strategies of (+) strand ssRNA viruses
Chairs: Eric Snijder, Jacques Rohayem
| |
| 14:30-15:10 |
| Dorothea Sawicki - Alphavirus Minus Strand Template Synthesis: An Interplay Between Virus and Host |
|
| 15:10-15:50 |
| Tero Ahola - Functions of alphavirus RNA replication proteins |
|
| 15:50-16:10 | Break |
| 16:10-16:50 |
| Eric Snijder - Arteriviruses, a perfect nidovirus role model? |
|
| 16:50-17:30 |
| John Ziebuhr - Enzymes involved in coronavirus replication |
|
| 17:30-17:50 |
| Frank van Kuppeveld - Membrane rearrangements in coxsackievirus infected cells |
|
|
| Tuesday August 28, 2007 |
| 09:00-12:30 |
Session 2: Replication strategies of (-) strand ssRNA viruses
Chairs: Sonia Longhi, Laurent Roux
| |
| 09:00-09:40 |
| Michael Buchmeier - The elegant complexity of the arenavirus life cycle |
|
| 09:40-10:20 |
| Juan Ortin - Influenza virus replication and gene expression |
|
| 10:20-10:50 | Coffee break |
| 10:50-11:30 |
|
| 11:30-12:10 |
| Hervé Bourhy - Evolution of rhabdoviridae |
|
| 12:10-12:30 |
| Richard Elliott - Exploiting bunyavirus reverse genetics to explore viral replication |
|
| 12:30-15:00 | Lunch break and Poster session 1 |
| 15:00-18:10 |
Session 3: Selected talks
Chairs: Ernest Gould, Christian Cambillau
| |
| 15:00-15:20 |
| Hélène Verheije - Murine hepatitis coronavirus co-opts the BFA-sensitive GBF1-controlled pathway to ensure efficient RNA replication |
|
| 15:20-15:40 |
| Jamie Arnold - A general acid in polymerase catalyzed nucleotidyl transfer rections |
|
| 15:40-16:00 |
| Nuria Verdaguer - Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase |
|
| 16:00-16:20 |
| Peter Sarin - Dissecting the Activities of the Bacteriophage Phi6 |
|
| 16:20-16:50 | Break |
| 16:50-17:10 |
| Carla Sousa - An anti-viral peptide inhibitor active against picornaviral 2A proteinases but not cellular caspases |
|
| 17:10-17:30 |
| Elena Gazina - Amiloride derivatives inhibit coxsackievirus B3 RNA replication |
|
| 17:30-17:50 |
| Stephen Curry - New structural and functional insights into a picornaviral IRES trans-acting factor, Ebp1 |
|
| 19:30 | Heuriger dinner |
|
| Wednesday August 29, 2007 |
| 09:00-12:30 |
Session 4: Virus evolution
Chairs: Ernest Gould, Raul Andino
| |
| 09:00-09:40 |
| Alexander Gorbalenya - RNA virus evolution: from species in the making to ancient enzymes |
|
| 09:40-10:20 |
| Oliver Pybus - The Evolutionary Genomics of RNA Viruses |
|
| 10:20-10:50 | Coffee break |
| 10:50-11:30 |
| Xavier de Lamballerie - Recent advances in genomics of flaviviruses |
|
| 11:30-12:10 |
| Peter Nagy - Host proteins affecting RNA virus recombination |
|
| 12:10-12:30 |
| Peiqiu Chen - From Diffusion to RNA Virus' Mutation and Evolution |
|
| 12:30-12:50 |
| Christian Riepl - Two non-infectious flaviviruses can form an infectious alliance |
|
| 12:50-15:00 | Lunch break and Poster session 2 |
| 15:00-18:20 |
Session 5: RNA polymerases
Chairs: Johan Neyts, Paul Tucker
| |
| 15:00-15:40 |
| Craig Cameron - RNA-dependent RNA polymerase (in)fidelity: Mechanisms, consequences and applications |
|
| 15:40-16:20 |
| Dennis Bamford - Bacterial dsRNA virus polymerases and their usage to combat viral diseases through RNAi |
|
| 16:20-16:40 | Break |
| 16:40-17:20 |
| Laurent Roux - To replicate or to transcribe, here is a good question for the Paramyxovirus RNA polymerase |
|
| 17:20-18:00 |
| Sonia Longhi - Functional role of intrinsic disorder within the replicative complex of measles virus |
|
| 18:00-18:20 |
| Isabelle Jupin - Phosphorylation of viral RNA-dependent RNA polymerase at specific sites and its role in replication of a plusstrand RNA virus |
|
| 20:00 | Conference dinner |
|
| Thursday August 30, 2007 |
| 09:00-12:40 |
Session 6: The quest for antivirals
Chairs: Bruno Canard, Kristina Djinovic
| |
| 09:00-09:40 |
| Johan Neyts - Development of selective inhibitors of RNA virus replication |
|
| 09:40-10:20 |
| Stefania de Marco - Inhibitors of Hepatitis C virus NS3 protease and NS5B polymerase |
|
| 10:20-10:50 | Coffee |
| 10:50-11:30 |
| Dieter Blaas - Structural Basis of Rhinovirus Receptor Function |
|
| 11:30-12:10 |
| Rolf Hilgenfeld - Structure-based discovery of inhibitors for proteases of RNA viruses |
|
| 12:10-12:30 |
| Rupert Russell - Fragment screening via crystallography against Influenza viruses |
|
| 12:30-12:40 |
|
| 12:40-14:00 | Lunch |
|
