| Thursday September 4 |
| 14:00 |
| Matthias Wilmanns, EMBL Hamburg, Germany |
| Welcome and Introduction |
|
|
Session 1: Complementary methods in Structural Biology |
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Chairs: Dmitri Svergun, Peter Timmins
|
| 14:15 |
| Peter Timmins, ILL, Grenoble, France |
| Small-angle scattering: the complementarity of X-rays and Neutrons |
|
| 14:45 |
| Jan Skov Pedersen, Aarhus University, Denmark |
| Laboratory Solution SAXS on Protein and Protein-RNA Structures Complexes as an Indispesable Complementary Tool to Crystallographic Methods |
|
| 15.15 |
| Olwyn Byron, University of Glasgow, UK |
| AUC - Analytical UltraCentrifugation And Universally Complementary |
|
| 15:45 |
| Joe Zaccai, ILL, France |
| Neutron scattering to measure molecular dynamics in cells |
|
| 16:15 | Coffee break |
| 16:45 |
| Martin Weik, IBS/LBM, France |
| Structural protein dynamics by crystallography and complementary methods |
|
| 17:15 |
| Gilad Haran, Weizmann Institute of Science, Israel |
| What single-molecule fluorescence spectroscopy teaches us about denatured proteins and their folding |
|
| 17:45 |
| Lev Weiner, Weizmann Institute of Science, Israel |
| Application of modern ESR/EPR in study of proteins folding and structure |
|
| 18:30 |
|
| 19:30 | Dinner |
|
| Friday September 5 |
|
Session 2: Intrinsically Unfolded Proteins in Structural Biology |
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Chairs: Joel Sussman, Peter Tompa
|
| 08:30 |
| Peter Tompa, Hungarian Academy of Sciences, Budapest, Hungary |
| TBA |
|
| 09:00 |
| Martin Blackledge, IBS/LBM, France |
| TBA |
|
| 09:30 |
| David Jones, University College London, UK |
| Disordered proteins in the human genome: regulation, modularity and function |
|
| 10:00 |
| Guy Lippens, University of Lille, France |
| The neuronal Tau protein : function without an obvious structure |
|
| 10:30 | Coffee break |
| 11:00 |
| Laurence Barron, University of Glasgow, UK |
| Structure and Behaviour of Unfolded Proteins from Raman Optical Activity |
|
| 11:30 |
| Frans Mulder University of Groningen, Netherlands |
| NMR techniques detect local structure in the disordered domain of autism-associated protein neuroligin-3 |
|
| 12:00 |
| Lucia Bianci, University of Florence, Italy |
| NMR and other techniques to characterize unstructured proteins |
|
| 12:30 | Lunch break |
|
|
Session 3: Applications in Structural Biology |
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Chairs: Matthias Wilmanns, Israel Silman
|
| 14:00 |
| Joel Sussman, Weizmann Institute of Science, Rehovot, Israel |
| TBA |
|
| 14:30 |
| Alan Fersht, University of Cambridge, UK |
| Structural Biology of the Tumour Suppressor p53 |
|
| 15.00 |
| Kristina Djinovic, University of Vienna, Austria |
| Towards a structural picture of muscle Z-disk: an integrative approach |
|
| 15:30 |
| Rob Russell (TBC), EMBL Heidelberg, Germany |
| TBA |
|
| 16:00 | Coffee break |
| 16:30 |
| Dmitri Svergun, EMBL Hamburg, Germany |
| TBA |
|
| 17:00 |
| Eckhard Mandelkow (TBC), DESY, Hamburg, Germany |
| Structural studies on Tau - a natively unfolded protein involved in Alzheimer disease. |
|
| 17:30 |
|
