Current project            Publication            Presentation               Previous work

 

56. Schwarz, C., Tschapek, B., Jumpertz, T., Jenewein, S., Lecher, J., Willbold, D., Panjikar S. Holland, B., Smits, S., Schmitt, L., Crystallisation and preliminary X-ray crystallographic studies of an oligomeric species of a refolded C39 peptidase-like domain of the Escherichia coli ABC transporter Haemolysin B Acta Cryst. F 2011 in press.

55. de Sanctis, D. Tucker, P.A., Panjikar S. Additional phase information from UV damage of SeMet labeled proteins J. Sync. Rad. 2011 in press.

54. Panjikar S., Mayerhofer, H., Tucker, P.A., Mueller-Dieckmann, J., de Sanctis, D. Single isomorphous replacement phasing of Selenomethionine containing proteins using UV induced radiation damage Acta Cryst., 2011 D67, 32-44.

53. King-Scott J., Konarev, P.V., Panjikar S., Jordanova, R., Svergun, D.I, Tucker, P.A., Structural Characterization of the Multidomain Regulatory Protein Rv1364c from Mycobacterium tuberculosis Structure 2011 V19, 56-69.

52. Zander, U., Faust, A., Klink, B.U., de Sanctis, D., Panjikar S., Quentmeier, A., Bardischewsky, F. , Friedrich, C.G., Scheidig, A.J. Structural basis for the oxidation of protein-bound sulfur by the sulfu cycle molybdohemo-enzyme sulfane dehydrogenase SOXCD J. Biol. Chem. 2010 In press.

51. Faust, A., Puhringer, S., Darowski, N., Panjikar S. Diederichs, K., Muller, U., Weiss, M., Update on the Tutorial for Learning and Teaching Macromolecular Crystallography J. Appl. Cryst. 2010 43, 1230-1237.

50. Jeyakanthan, J., Thamotharan, S., Panjikar S. Kitamura, Y., Noriko, N., Shinkai, A., Kuramitsu, S., Yokoyama, S., Expression, purification and X-ray analysis of 1,3-Propanediol Dehydrogenase (Aq_1145) from Aquifex aeolicus VF5 Acta Cryst. F 2010 F66, 184-186

49. Manjasetty, B., Turnbull, A.P., Panjikar S. The impact of Structural Proteomics on Biotechnology Biotechnology and Genetic Engineering Reviews 2010, vol. 26, pp. 353-370

48. Panjikar S., Parthasarathy, V., Lamzin, V., Weiss, M.S., Tucker, P.A., On the combination of molecular replacement and single anomalous diffraction phasing for automated structure determination Acta Cryst. D 2009 D65, 1089-1097.

47. Manolaridis, I. , Wojdyla, J., Panjikar S., Snijder, E.J., Gorbalenya, A.E., Berglind, H., Nordlund, P., Coutard, B., Tucker, P.A., Structure of the C-terminal domain of nsp4 from Feline Coronavirus Acta Cryst. D 2009 D65 411-420.

46. Liuqing, Y. , Marco, H., Panjikar S., Meitian, W., Soteckigt, J., Structural Basis and enzymatic Mechanism of the Biosynthesis of C9 from C10 monoterpenoid Indole Alkaloids J. Angewandte Chemi 2009 48(28):5211-5213.

45. Van Molle I. , Moonens, K., Buts, A., Garcia Pino, A., Panjikar S., Wyns, L., De Greve, H., Bouckaert, J., The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces. Acta Cryst. D 2009 D65, 411-420.

44. Janowski, R., Panjikar S., Eddine, A.N., Kaufmann, S.H., Weiss, M.S., Structural analysis reveals DNA binding properties of Rv2827c, a hypothetical protein from Mycobacterium tuberculosis. J. Struct. Funct. Genomics. 2009 10(2):137-150.

43. Lapkouski, M., Panjikar S., Janscak, P., Smatanova, I.K., Carey, J., Ettrich, R., Csefalvay, E., Structure of the motor subunit of type I restriction-modification complex EcoR124I Nat. Struc. Mol. Bio. (2009). 16(1):94-95.

42. Jain, A., Ziegler, J. , Liscombe, D.K., Facchini, P.J., Tucker, P.A., Panjikar S., Purification, Crystallization and Preliminary X-ray Diffraction Analysis of Pavine N-Methyltransferase from Thalictrum flavum Acta Cryst. F (2008). 64, 1066-1069.

 

41. Faust, A., Panjikar S., Mueller, U. , Parthasarathy, V., Schmidt, A., Lamzin, V., Weiss, M.S., A tutorial for learning and teaching macromolecular crystallography J. Appl. Cryst. (2008). 41, 1161-1172.

40. Kursula, I., Kursula, P., Ganter, M., Panjikar S., Matuschewski, K. , Schueler, H., Structural basis for parasite-specific functions of the divergent profilin of Plasmodium falciparum Structure 2008 (2008). 16(11) 1638-1648.

39. Zhou,Y.F., Nan, B., Nan,J., Ma, Q., Panjikar S., Liang, Y.H., Wang,Y., Su, X.D. C(4)-Dicarboxylates Sensing Mechanism Revealed by the Crystal Structures of DctB Sensor Domain. J Mol Biol. (2008). in press

38. Monferrer, D., Tralau, T. , Kertesz, M. A. , Panjikar S., Ussn, I. High crystallizability under air-exclusion conditions of the full-length LysR-type transcriptional regulator TsaR from Comamonas testosteroni T-2 and data-set analysis for a MIRAS structure-solution approach Acta Cryst. (2008). F64, 764-769

37.   Martinez Rodriguez, S., Panjikar S., Van Belle, K., Wyns, L., Messens, J., Loris, R. Nonspecific base recognition mediated by water bridges and hydrophobic stacking in ribonuclease I from Escherichia coli Protein Science (2008) 17(4):681-90.

36.   Loris,E., Barleben L., Panjikar S., Stoeckigt J., 3D-Structure and Function of Strictosidine Synthase: the Key Enzyme of Monoterpenoid Indole Alkaloid Biosynthesis. Plant. Physiol. Biochem. (2008) 46(3):340-55. Review

 

35.   Vyas, R., Kumar, V., Panjikar S., Karthikeyan,S., Kishan, K.V.R., Tewari, R.I., Weiss, M.S. Purification, Crystallization and Preliminary X-ray Diffraction Analysis of Aspartate Semialdehyde Dehydrogenase (Rv3708c) from Mycobacterium tuberculosis. Acta Cryst. F. (2008) F64 167-70.

34.   Manjasetty, B. A. , Turnbull, A. , Panjikar S. Buessow K., Chance, M. R. Automated Technologies and Novel Techniques to Accelerate Protein Crystallography for Structural Genomics. Proteomics (2008) 8(4):612-25. Review Pubmed

33. Maresh, J., Giddings, L., Friedrich, A., Loris, E., Panjikar S. Trout, B., Stoeckigt, J., Peters, B., O'Connor, S. Strictosidine Synthase: Mechanism of a Pictet-Spengler Catalyzing Enzyme. Journal of the American Chemical Society (2008) 30(2):710-723. Pubmed

 

32.   Stoeckigt, J., Panjikar S. Structural biology in plant natural product biosynthesis - Architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis. Natural Product Reports (2007) 24(6):1382-1400. Review Pubmed

 

31.   Brzezinski, K., Stepkowski, T., Panjikar S., Bujacz, G., Jaskolski, M., High-resolution structure of fucosyltransferase involved in the biosynthesis of the nodulation factor. Acta Biochimica Polonica (2007) 54(3):537-549. Pubmed

 

30.   King-Scott, J., Nowak, E., Panjikar S., Mylonas, E., Roessle, M., Svergun, D.I, Tucker, P.A., The structure of a full-length response regulator from Mycobacterium Tuberculosis in a stabilised domain swapped, activated state. J. Biol. Chem. (2007) 282(52):37717-37729. Pubmed

 

29.   Barleben L., Panjikar S., Ruppert, M., Koepke, J. , Stoeckigt J., Molecular Architecture of Strictosidine Glucosidase the Gateway to the Biosynthesis of the Monoterpenoid Indole Alkaloid Family . The Plant Cell (2007) 19(9):2886-2897. (Joint first author) Pubmed

 

28.   Elke L., Panjikar S., Ruppert, M., Barleben L., Unger, M., Stoeckigt J., Structure based engineering of strictosidine synthase - Auxiliary of new alkaloid libraries . Chemistry & Biology (2007) 14(9):979-985 Pubmed

 

27.   Lapkouski M., Panjikar S., Smatanova, I.K., Csefalvay, E., Purification, crystallization and preliminary X-ray analysis of the HsdR subunit of the EcoR124I endonuclease from Escherichia coli . Acta Cryst. F. (2007) F63. 582-585. Pubmed

 

26.   Koh C.S., Didierjean C., Navrot N., Panjikar S., Carlin G. M., Rouhier N., Jacquot J.P., Corbie C. Crystal structures of poplar glutathione peroxidase 5, a thioredoxin-dependent enzyme:Insights to redox-conformationation changes and new mode of oligomerization . J. Mol. Bio. (2007) 370(3):512-529. Pubmed

 

25.   Singh R.K. Gottfried J. P. Panjikar S., Winfried H. Structure of the apo-form of the catabolite control protein A, CcpA, from Bacillus megaterium with the DNA binding domain . Acta Cryst. F. (2007) Pt (4):253-7. Pubmed

 

24.  Van Molle, I., Joensuu, J.J., Buts, L., Panjikar S., Kotiaho, M., Bouckaert, J. , Wyns, L. Niklander-Teeri, V. De Greve, H. Chloroplasts assemble the major subunit FaeG of Escherichia coli F4 (K88) fimbriae to strand-swapped dimers . J. Mol. Bio. (2007) 368(3):791-9. Pubmed

 

23.  Mueller-Dieckmann C., Panjikar S., Schmidt A., Mueller S., Kuper J., Geerlof A., Wilmanns M. Singh R.K. Tucker, P.A. Weiss M.S. On the Routine Use of Soft X-Rays in Macromolecular Crystallography, Part IV - Efficient Determination of Anomalous Substructures in Bio-Macromolecules Using Longer X-ray Wavelengths . Acta Cryst. D. (2007) D63, 366-380. Pubmed

 

22.  Stoeckigt, J. Panjikar, S., Ruppert, M., Barleben, L., Ma, X. Loris, E., & Hill M. The molecular architecture of major enzymes from ajmaline biosynthesic pathway. Phytochem. Rev. (2007) Volume 6, Number 1, 15-34.

 

21.  Yu Y., Liang Y.H., Brostromer E., Quan J.M., Panjikar S., Dong Y.H., Su X.D. A Catalytic Mechanism Revealed by the Crystal Structures of the Imidazolonepropionase from Bacillus subtilis. . J. Biol. Chem. (2006). 281(48):36929-36936. Pubmed

 

20.  Rosenthal C., Mueller U. Panjikar S., Sun L., Ruppert M., Zhao Y., Stockigt J. Expression, purification, crystallization and preliminary X-ray analysis of perakine reductase, a new member of the aldo-keto reductase enzyme superfamily from higher plants. Acta Cryst. (2006). F62, 1286-1289. Pubmed

 

19.  Stout J., De Smet L., Panjikar, S., Weiss M.S., Savvides S.N., Van Beeumen J. Crystallization, preliminary crystallographic analysis and phasing of the thiosulfate-binding protein SoxY from Chlorobium limicola f. thiosulfatophilum. . Acta Cryst. (2006). F62, 1093-1096. Pubmed

 

18. Ranaivoson, F. M., Kauffmann, B., Neiers, F., Wu, J. Bischi-Muller, S., Panjikar, S., Aubry, A., Branlant, G., & Favier, F. The X-ray Structure of the N-terminal Domain of PILB from Neisseria meningitidis REveals a Thioredoxin-fold. J. Mol. Biol. (2006). 358(2):443-54. Pubmed

 

17. Ma, X.,Panjikar, S., Koepke, J., Loris E. & Stöckigt, J. The Structure of Rauvolfia serpentina Strictosidine Synthase Is a Novel 6-Bbladed a-Propeller Fold in Plant Proteins The Plant Cell, (2006). 18(4) 907-920. (Joint first author). Pubmed

 

16. Ruppert, M., Panjikar, S., Barleben, L., and Stoeckigt, J. Heterologous expression, purification, crystallisation and preliminary X-ray analysis of raucaffricine glucosidase – a plant enzyme specifically involved in Rauvolvia alkaloid biosynthesis. Acta Cryst. (2006). F62, 257-260. Pubmed

 

15. Nowak, E., Panjikar, S., Morth, J. P., Jordanova, R., & Tucker, P. A. Structural and Functional Aspects of the Sensor Histidine Kinase, PrrB from Mycobacterium tuberculosis. Structure, (2006) Vol 14, 275-285. Pubmed

 

14. Nowak, E., Panjikar, S., Konarev, P., Svergun, D. J. & Tucker, P. A. The structural basis of signal transduction for the response regulator PrrA from mycobacterium tuberculosis. J. Biol. Chem. (2006). 281(14):9659-9666.  Pubmed

 

13. Mueller-Dieckmann, C., Panjikar, S., Tucker, P. A.,   & Weiss, M. S. On the routine use of soft X-rays in macromolecular crystallography, part III - The Optimal data collection wavelength. Acta Cryst. D (2005) D61, 1263-1272. Pubmed

 

12. Datta,A. B., Panjikar, S., Weiss, M. S., Chakrabarti,  & P. Parrack. Unique quaternary organisation of transcription activator lamda CII: basis for its direct repeat recognition. Proc Natl Acad Sci U S A. (2005) 102, 11242-11247. Pubmed

 

11. Kafala, G., Janowski, R. Panjikar, S., Mueller-dieckmann C.   & Weiss, M. S., Clonning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DapB (Rv2773) from Mycobacterium tuberculosis. Acta Cryst. F61 (2005) 718-721. Pubmed

 

10. Panjikar, S., Parthasarathy, V., Lamzin, V. S., Weiss, M. S.  & Tucker, P. A. . Auto-Rickshaw - An automated crystal structure determination platform as an efficient tool for the validation of an X-ray diffraction experiment. Acta Cryst. D61 (2005) 449-457. Pubmed

 

9. Ma, X., Koepke, J., Panjikar, S., Fritzsch, G,. Stöckigt, J.: Crystal structure of vinorine synthase, the first represantative of the BAHD superfamily. J. Biol. Chem., 2005, 14 13576-13583.PubMed

 

8. Weiss, M.S., Panjikar, S., Mueller-Dieckmann, C. & Tucker, P.A. On the influence of the incident photon energy on the radiation damage in crystalline biological samples. J Synchr Rad, (2005) 12, 304-309. Pubmed

 

7. Mapelli, M., Panjikar, S. & Tucker, P.A. The crystal structure of the HSV-1 ssDNA binding protein suggests the structural basis for flexible, cooperative single-stranded DNA binding. J Biol Chem (2005) 2990-2997. PubMed   (Joint first Author).

 

6. Mueller-Dieckmann, C., Polentarutti, M., Djinovic Carugo, K., Panjikar, S., Tucker, P.A. & Weiss, M.S. On the routine use of soft X-rays in macromolecular crystallography. Part II. Data-collection wavelength and scaling models. Acta Cryst. (2004) D60 28-38. PubMed

 

5. Weiss, M. S.,  Panjikar S.,  E. Nowak and Paul Tucker, Metal binding to porcine pancreatic elastase: calcium or not calcium , Acta Cryst. (2002) D58, 1407-1412. Pubmed

 

4. Panjikar, S. and Tucker, P. Xenon derivatization of halide-soaked protein crystals , Acta Cryst. (2002) D58, 1413-1420. Pubmed

 

3. Panjikar, S. and Tucker, P. Phasing possiblities using different wavelengths with a xenon derivative, J. Appl. Cryst., (2002) 35, 261-266.

 

2. Panjikar, S. and Tucker, P. Use of paraffin oil and Panjelly in xenon derivatisation, J. Appl. Cryst., (2002) 35, 117-119.

 

1. Santosh Panjikar, Margaret Biswas and Saraswathi Vishveshwara Determinants of Backbone Packing in Globular Proteins: An analysis of spatial neighbours, Acta Cryst., (1997) D53, 627-637. Pubmed

 

 

Last update on 12.02.2009

 

Structure in PDB