Total number of publications with IF > 9 (162) : 162 [ as of 05/10/2022 ]

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2022


162: Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding.
Hyjek-Składanowska M, Anderson BA, Mykhaylyk V, Orr C, Wagner A, Poznański JT, Skowronek K, Seth P, Nowotny M.
Nucleic Acids Res. (2022 Sep)UNK:gkac774
DOI: 10.1093/nar/gkac774  |   PUBMED: 36124719  |   IF(2018) = 11.1
PDB [P13]:  7ZVN   

161: Structure of an MHC I-tapasin-ERp57 editing complex defines chaperone promiscuity.
Müller IK, Winter C, Thomas C, Spaapen RM, Trowitzsch S, Tampé R.
Nat Commun. (2022 Sep)13:5383
DOI: 10.1038/s41467-022-32841-9  |   PUBMED: 36104323  |   IF(2022) = 14.9
PDB [13]:  7QNG   

160: Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Zeke A, Takács T, Sok P, Németh K, Kirsch K, Egri P, Póti ÁL, Bento I, Tusnády GE, Reményi A.
Nat Commun. (2022 Sep)13:5439
DOI: 10.1038/s41467-022-32918-5  |   PUBMED: 36114179  |   IF(2022) = 14.9
PDB [P14]:  7PPL  7PPM  7PPN   

159: Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Figiel M, Gapińska M, Czarnocki-Cieciura M, Zajko W, Sroka M, Skowronek K, Nowotny M.
Nucleic Acids Res. (2022 Sep)50:10026-10040
DOI: 10.1093/nar/gkac772  |   PUBMED: 36107766  |   IF(2018) = 11.1
PDB [P14]:  7R07   

158: A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host.
Alexa A, Sok P, Gross F, Albert K, Kobori E, Póti ÁL, Gógl G, Bento I, Kuang E, Taylor SS, Zhu F, Ciliberto A, Reményi A.
Nat Commun. 2022 Jan 25;13(1):472.
DOI: 10.1038/s41467-022-28109-x  |   PUBMED: 35078976  |   IF(2022) = 14.9
PDB [P14]:  7OPO  7OPM   

157: Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.
Truongvan N, Li S, Misra M, Kuhn M, Schindelin H.
Nat Commun. (2022 Aug)13:4789
DOI: 10.1038/s41467-022-32040-6  |   PUBMED: 35970836  |   IF(2022) = 14.9
PDB [P14]:  7PVN   

156: An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.
Baker YR, Thorpe C, Chen J, Poller LM, Cox L, Kumar P, Lim WF, Lie L, McClorey G, Epple S, Singleton D, McDonough MA, Hardwick JS, Christensen KE, Wood MJA, Hall JP, El-Sagheer AH, Brown T.
Nat Commun. (2022 Jul)13:4036
DOI: 10.1038/s41467-022-31636-2  |   PUBMED: 35821218  |   IF(2022) = 14.9
PDB [P13]:  7OZZ  7OOS   

155: Direct interaction of a chaperone-bound type III secretion substrate with the export gate.
Gilzer D, Schreiner M, Niemann HH.
Nat Commun. (2022 Jun)13:2858
DOI: 10.1038/s41467-022-30487-1  |   PUBMED: 35654781  |   IF(2022) = 14.9
PDB [P13]:  7QIJ   

154: Widespread occurrence of covalent lysine-cysteine redox switches in proteins.
Rabe von Pappenheim F, Wensien M, Ye J, Uranga J, Irisarri I, de Vries J, Funk LM, Mata RA, Tittmann K.
Nat Chem Biol. (2022 Feb)UNK:pp. UNK
DOI: 10.1038/s41589-021-00966-5  |   PUBMED: 35165445  |   IF(2020) = 41.8
PDB [P14]:  7ODO  7ODQ  7O9G  7ODP  7OEY   

Number of publications for 2022: 9


2021


153: Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms.
Ornik-Cha A, Wilhelm J, Kobylka J, Sjuts H, Vargiu AV, Malloci G, Reitz J, Seybert A, Frangakis AS, Pos KM.
Nat Commun. (2021 Nov)12:6919
DOI: 10.1038/s41467-021-27146-2  |   PUBMED: 34824229  |   IF(2022) = 14.9
PDB [P13P14]:  7B8R  7B8S   

152: The elusive Rhizobium etli L-asparaginase has a novel fold and peculiar active site
Loch JI, Imiolczyk B, Sliwiak J, Wantuch A, Bejger M, Gilski M, Jaskolski M
Nat Commun. (2021 Nov)12:6717
DOI: 10.1038/s41467-021-27105-x  |   PUBMED: 34795296  |   IF(2022) = 14.9
PDB [P13]:  7OS5  7OS3  7OS6   

151: Profiling cellular diversity in sponges informs animal cell type and nervous system evolution.
Musser JM, Schippers KJ, Nickel M, Mizzon G, Kohn AB, Pape C, Ronchi P, Papadopoulos N, Tarashansky AJ, Hammel JU, Wolf F, Liang C, Hernández-Plaza A, Cantalapiedra CP, Achim K, Schieber NL, Pan L, Ruperti F, Francis WR, Vargas S, Kling S, Renkert M, Polikarpov M, Bourenkov G, Feuda R, Gaspar I, Burkhardt P, Wang B, Bork P, Beck M, Schneider TR, Kreshuk A, Wörheide G, Huerta-Cepas J, Schwab Y, Moroz LL, Arendt D.
Science. 2021 Nov 5;374(6568):717-723.
DOI: 10.1126/science.abj2949.  |   PUBMED: 34735222.  |   IF(2018) = 41.1
PDB [P14]:   

150: Structural basis of cytokine-mediated activation of ALK family receptors.
De Munck S, Provost M, Kurikawa M, Omori I, Mukohyama J, Felix J, Bloch Y, Abdel-Wahab O, Bazan JF, Yoshimi A, Savvides SN.
Nature. (2021 Oct 13). Epub ahead of print
DOI: 10.1038/s41586-021-03959-5  |   PUBMED: 34646012  |   IF(2018) = 43.1
PDB [P13P14]:  7NX4  7NX2  7NX1   

149: The CTPase activity of ParB determines the size and dynamics of prokaryotic DNA partition complexes.
Osorio-Valeriano M, Altegoer F, Das CK, Steinchen W, Panis G, Connolley L, Giacomelli G, Feddersen H, Corrales-Guerrero L, Giammarinaro PI, Hanßmann J, Bramkamp M, Viollier PH, Murray S, Schäfer LV, Bange G, Thanbichler M.
Mol Cell. (2021 Oct)81:3992-4007.e10
DOI: 10.1016/j.molcel.2021.09.004  |   PUBMED: 34562373  |   IF(2018) = 14.5
PDB [P14]:  7BNR   

148: Engineering a Highly Efficient Carboligase for Synthetic One-Carbon Metabolism.
Nattermann M, Burgener S, Pfister P, Chou A, Schulz L, Lee SH, Paczia N, Zarzycki J, Gonzalez R, Erb TJ.
ACS Catal. (2021 May)11:5396-5404
DOI: 10.1021/acscatal.1c01237  |   PUBMED: 34484855  |   IF(2018) = 12.1
PDB [P13]:  7B2E   

147: BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture.
Bandera AM, Bartho J, Lammens K, Drexler DJ, Kleinschwärzer J, Hopfner KP, Witte G.
Nucleic Acids Res. (2021 Sep)49:10166-10177
DOI: 10.1093/nar/gkab736  |   PUBMED: 34432045  |   IF(2018) = 11.1
PDB [P13P14]:  7B5U  7B5T  7B5W   

146: Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD.
Fauser J, Gulen B, Pogenberg V, Pett C, Pourjafar-Dehkordi D, Krisp C, Höpfner D, König G, Schlüter H, Feige MJ, Zacharias M, Hedberg C, Itzen A.
Nat Commun. (2021 Apr)12:2426
DOI: 10.1038/s41467-021-22596-0  |   PUBMED: 33893288  |   IF(2022) = 14.9
PDB [P13]:  6ZMD   

145: Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli.
Hamborg L, Granata D, Olsen JG, Roche JV, Pedersen LE, Nielsen AT, Lindorff-Larsen K, Teilum K.
Commun Biol. (2021 Aug)4:980
DOI: 10.1038/s42003-021-02490-7  |   PUBMED: 34408246  |   IF(2019) = 12.1
PDB [P13P14]:  7A3M  7AON  7AOK   

144: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Verstraete K, Verschueren KHG, Dansercoer A, Savvides SN.
Nat Struct Mol Biol. 2021 Aug;28(8):636-638. Epub 2021 Jul 22.
DOI: 10.1038/s41594-021-00624-3  |   PUBMED: 34294920  |   IF(2019) = 11.7
PDB [P14]:  6ZNW   

143: Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography.
Geier B, Oetjen J, Ruthensteiner B, Polikarpov M, Gruber-Vodicka HR, Liebeke M.
Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2023773118.
DOI: 10.1073/pnas.2023773118.  |   PUBMED: 34183413   |   IF(2019) = 9.4
PDB [P14]:   

142: Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners.
Marcelot A, Petitalot A, Ropars V, Le Du MH, Samson C, Dubois S, Hoffmann G, Miron S, Cuniasse P, Marquez JA, Thai R, Theillet FX, Zinn-Justin S.
Nucleic Acids Res. (2021 Apr)49:3841-3855
DOI: 10.1093/nar/gkab184  |   PUBMED: 33744941  |   IF(2018) = 11.1
PDB [P14]:  7ABM   

141: Structure of the mycobacterial ESX-5 type VII secretion system pore complex.
Beckham KSH, Ritter C, Chojnowski G, Ziemianowicz DS, Mullapudi E, Rettel M, Savitski MM, Mortensen SA, Kosinski J, Wilmanns M.
Sci Adv. 2021 Jun 25;7(26):eabg9923.
DOI: 10.1126/sciadv.abg9923  |   PUBMED: 34172453  |   IF(2018) = 12.5
PDB [P13]:  7B7J   

140: Allosteric drug transport mechanism of multidrug transporter AcrB.
Tam HK, Foong WE, Oswald C, Herrmann A, Zeng H, Pos KM.
Nat Commun. (2021 Jun)12:3889
DOI: 10.1038/s41467-021-24151-3  |   PUBMED: 34188038  |   IF(2022) = 14.9
PDB [P13]:  6ZOG   

139: Discovery of fungal surface NADases predominantly present in pathogenic species.
Strømland Ø, Kallio JP, Pschibul A, Skoge RH, Harðardóttir HM, Sverkeli LJ, Heinekamp T, Kniemeyer O, Migaud M, Makarov MV, Gossmann TI, Brakhage AA, Ziegler M.
Nat Commun. (2021 Mar)12:1631
DOI: 10.1038/s41467-021-21307-z  |   PUBMED: 33712585  |   IF(2022) = 14.9
PDB [P13]:  6YGE   

138: Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin.
Sponga A, Arolas JL, Schwarz TC, Jeffries CM, Rodriguez Chamorro A, Kostan J, Ghisleni A, Drepper F, Polyansky A, De Almeida Ribeiro E, Pedron M, Zawadzka-Kazimierczuk A, Mlynek G, Peterbauer T, Doto P, Schreiner C, Hollerl E, Mateos B, Geist L, Faulkner G, Kozminski W, Svergun DI, Warscheid B, Zagrovic B, Gautel M, Konrat R, Djinović-Carugo K.
Sci Adv. 2021 May 28; 7(22):eabg7653.
DOI: 10.1126/sciadv.abg7653  |   PUBMED: 34049882  |   IF(2018) = 12.5
PDB [P14]:  7A8T   

137: Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.
Sekulovski S, Devant P, Panizza S, Gogakos T, Pitiriciu A, Heitmeier K, Ramsay EP, Barth M, Schmidt C, Tuschl T, Baas F, Weitzer S, Martinez J, Trowitzsch S.
Nat Commun. 2021 Sep 28;12(1):5610.
DOI: 10.1038/s41467-021-25870-3  |   PUBMED: 34584079  |   IF(2022) = 14.9
PDB [P14]:  6Z9U   

136: Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Yperman K, Papageorgiou AC, Merceron R, De Munck S, Bloch Y, Eeckhout D, Jiang Q, Tack P, Grigoryan R, Evangelidis T, Van Leene J, Vincze L, Vandenabeele P, Vanhaecke F, Potocký M, De Jaeger G, Savvides SN, Tripsianes K, Pleskot R, Van Damme D.
Nat Commun. (2021 May)12:3050
DOI: 10.1038/s41467-021-23314-6  |   PUBMED: 34031427  |   IF(2022) = 14.9
PDB [P14]:  6YIG   

135: TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation.
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D.
Mol Cell. (2021 Apr)UNK:pp. UNK
DOI: 10.1016/j.molcel.2021.04.019  |   PUBMED: 33974911  |   IF(2018) = 14.5
PDB [P13]:  7A0N   

134: Molecular basis for the allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
Wurm JP, Sung S, Kneuttinger AC, Hupfeld E, Sterner R, Wilmanns M, Sprangers R.
Nat Commun. (2021 May)12:2748
DOI: 10.1038/s41467-021-22968-6  |   PUBMED: 33980881  |   IF(2022) = 14.9
PDB [P13]:  7AC8   

133: A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Wensien M, von Pappenheim FR, Funk LM, Kloskowski P, Curth U, Diederichsen U, Uranga J, Ye J, Fang P, Pan KT, Urlaub H, Mata RA, Sautner V, Tittmann K.
Nature. 2021 May;593(7859):460-464. Epub 2021 May 5.
DOI: 10.1038/s41586-021-03513-3  |   PUBMED: 33953398  |   IF(2018) = 43.1
PDB [P14]:  6ZWJ  7BBW  7BBX  6ZWF  6ZX4  6ZWH   

132: X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.
Günther S, Reinke PYA, Fernández-García Y, Lieske J, Lane TJ, Ginn HM, Koua FHM, Ehrt C, Ewert W, Oberthuer D, Yefanov O, Meier S, Lorenzen K, Krichel B, Kopicki JD, Gelisio L, Brehm W, Dunkel I, Seychell B, Gieseler H, Norton-Baker B, Escudero-Pérez B, Domaracky M, Saouane S, Tolstikova A, White TA, Hänle A, Groessler M, Fleckenstein H, Trost F, Galchenkova M, Gevorkov Y, Li C, Awel S, Peck A, Barthelmess M, Schluenzen F, Lourdu Xavier P, Werner N, Andaleeb H, Ullah N, Falke S, Srinivasan V, França BA, Schwinzer M, Brognaro H, Rogers C, Melo D, Zaitseva-Doyle JJ, Knoska J, Peña-Murillo GE, Mashhour AR, Hennicke V, Fischer P, Hakanpää J, Meyer J, Gribbon P, Ellinger B, Kuzikov M, Wolf M, Beccari AR, Bourenkov G, von Stetten D, Pompidor G, Bento I, Panneerselvam S, Karpics I, Schneider TR, Garcia-Alai MM, Niebling S, Günther C, Schmidt C, Schubert R, Han H, Boger J, Monteiro DCF, Zhang L, Sun X, Pletzer-Zelgert J, Wollenhaupt J, Feiler CG, Weiss MS, Schulz EC, Mehrabi P, Karničar K, Usenik A, Loboda J, Tidow H, Chari A, Hilgenfeld R, Uetrecht C, Cox R, Zaliani A, Beck T, Rarey M, Günther S, Turk D, Hinrichs W, Chapman HN, Pearson AR, Betzel C, Meents A.
Science. (2021 May 7) 372(6542):642-646
DOI: 10.1126/science.abf7945  |   PUBMED: 33811162  |   IF(2018) = 41.1
PDB [P14]:  7AXO   

131: Crystal structures of the EVE-HNH endonuclease VcaM4I in the presence and absence of DNA.
Pastor M, Czapinska H, Helbrecht I, Krakowska K, Lutz T, Xu SY, Bochtler M.
Nucleic Acids Res. (2021 Feb)49:1708-1723
DOI: 10.1093/nar/gkaa1218  |   PUBMED: 33450012  |   IF(2018) = 11.1
PDB [P13]:  6YKF   

130: Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison.
Mehrabi P, Bücker R, Bourenkov G, Ginn HM, von Stetten D, Müller-Werkmeister HM, Kuo A, Morizumi T, Eger BT, Ou WL, Oghbaey S, Sarracini A, Besaw JE, Pare-Labrosse O, Meier S, Schikora H, Tellkamp F, Marx A, Sherrell DA, Axford D, Owen RL, Ernst OP, Pai EF, Schulz EC, Miller RJD.
Sci Adv. (2021 Mar 17) 7(12):eabf1380
DOI: 10.1126/sciadv.abf1380  |   PUBMED: 33731353  |   IF(2018) = 12.5
PDB [P14]:  7A42  7A44   

129: Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Pannecoucke E, Van Trimpont M, Desmet J, Pieters T, Reunes L, Demoen L, Vuylsteke M, Loverix S, Vandenbroucke K, Alard P, Henderikx P, Deroo S, Baatz F, Lorent E, Thiolloy S, Somers K, McGrath Y, Van Vlierberghe P, Lasters I, Savvides SN.
Sci Adv. (2021 Mar)7:pp. UNK
DOI: 10.1126/sciadv.abe1682  |   PUBMED: 33771865  |   IF(2018) = 12.5
PDB [P14]:  6ZL1   

128: Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1.
Ruegenberg S, Mayr FAMC, Atanassov I, Baumann U, Denzel MS.
Nat Commun. (2021 Apr)12:2176
DOI: 10.1038/s41467-021-22320-y  |   PUBMED: 33846315  |   IF(2022) = 14.9
PDB [P13]:  6ZMK  7NDL   

127: Structural insights into the inhibition of glycine reuptake.
Shahsavar A, Stohler P, Bourenkov G, Zimmermann I, Siegrist M, Guba W, Pinard E, Sinning S, Seeger MA, Schneider TR, Dawson RJP, Nissen P.
Nature (2021 Mar)591:677-681
DOI: 10.1038/s41586-021-03274-z  |   PUBMED: 33658720  |   IF(2018) = 43.1
PDB [P14]:  6ZPL  6ZBV   

126: Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue.
Arkhipova V, Fu H, Hoorens MWH, Trinco G, Lameijer LN, Marin E, Feringa BL, Poelarends GJ, Szymanski W, Slotboom DJ, Guskov A.
J Am Chem Soc. (2021 Jan)143:1513-1520
DOI: 10.1021/jacs.0c11336  |   PUBMED: 33449695  |   IF(2018) = 14.7
PDB [P13]:  6ZLH  6ZGB  6ZL4   

125: Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production.
Venskutonytė R, Koh A, Stenström O, Khan MT, Lundqvist A, Akke M, Bäckhed F, Lindkvist-Petersson K.
Nat Commun. (2021 Mar)12:1347
DOI: 10.1038/s41467-021-21548-y  |   PUBMED: 33649331  |   IF(2022) = 14.9
PDB [P13]:  6T85   

124: Structural basis of Naa20 activity towards a canonical NatB substrate.
Layer D, Kopp J, Fontanillo M, Köhn M, Lapouge K, Sinning I.
Commun Biol. 2021 Jan 4;4(1):2.
DOI: 10.1038/s42003-020-01546-4.  |   PUBMED: 33398031  |   IF(2019) = 12.1
PDB [P14]:  6ZMP   

123: The amphibian antimicrobial peptide uperin 3.5 is a cross-α/cross-β chameleon functional amyloid
Salinas N, Tayeb-Fligelman E, Sammito MD, Bloch D, Jelinek R, Noy D, Usón I, Landau M
Proc Natl Acad Sci U S A. 118(3):e2014442118.
DOI: 10.1073/pnas.2014442118  |   PUBMED: 33431675  |   IF(2019) = 9.4
PDB [P14]:   

Number of publications for 2021: 31


2020


122: Restriction endonucleases that cleave RNA/DNA heteroduplexes bind dsDNA in A-like conformation.
Kisiala M, Kowalska M, Pastor M, Korza HJ, Czapinska H, Bochtler M.
Nucleic Acids Res. 2020 Jul 9;48(12):6954-6969.
DOI: 10.1093/nar/gkaa403.  |   PUBMED: 32459314  |   IF(2018) = 11.1
PDB [P13]:  6G3B   

121: High-resolution structural insights into the heliorhodopsin family.
Kovalev K, Volkov D, Astashkin R, Alekseev A, Gushchin I, Haro-Moreno JM, Chizhov I, Siletsky S, Mamedov M, Rogachev A, Balandin T, Borshchevskiy V, Popov A, Bourenkov G, Bamberg E, Rodriguez-Valera F, Büldt G, Gordeliy V.
Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4131-4141.
DOI: 10.1073/pnas.1915888117  |   PUBMED: 32034096  |   IF(2019) = 9.4
PDB [P14]:   

120: Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake.
Jakobi AJ, Huber ST, Mortensen SA, Schultz SW, Palara A, Kuhm T, Shrestha BK, Lamark T, Hagen WJH, Wilmanns M, Johansen T, Brech A, Sachse C.
Nat Commun. 2020 Jan 23;11(1):440.
DOI: 10.1038/s41467-020-14343-8  |   PUBMED: 31974402  |   IF(2022) = 14.9
PDB [P14]:   

119: HEPN-MNT Toxin-Antitoxin System: The HEPN Ribonuclease Is Neutralized by OligoAMPylation.
Songailiene I, Juozapaitis J, Tamulaitiene G, Ruksenaite A, Šulčius S, Sasnauskas G, Venclovas Č, Siksnys V.
Mol Cell. (2020 Dec)80:955-970.e7
DOI: 10.1016/j.molcel.2020.11.034  |   PUBMED: 33290744  |   IF(2018) = 14.5
PDB [P13]:  7AE6  7AE8  7AE9  7AE2   

118: Inhibition of urease, a Ni-enzyme: the reactivity of a key thiol with mono- and di-substituted catechols elucidated by kinetic, structural and theoretical studies.
Mazzei L, Contaldo U, Musiani F, Cianci M, Bagnolini G, Roberti M, Ciurli S.
Angew Chem Int Ed Engl. (2020 Nov)UNK:pp. UNK
DOI: 10.1002/anie.202014706  |   PUBMED: 33245574  |   IF(2019) = 13.0
PDB [P13]:  6ZNY  6ZNZ  6ZO1   

117: Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection.
Anjanappa R, Garcia-Alai M, Kopicki JD, Lockhauserbäumer J, Aboelmagd M, Hinrichs J, Nemtanu IM, Uetrecht C, Zacharias M, Springer S, Meijers R.
Nat Commun. (2020 Mar)11:1314
DOI: 10.1038/s41467-020-14862-4  |   PUBMED: 32161266  |   IF(2022) = 14.9
PDB [P14]:  6TDP  6TDO  6TDQ  6TDS  6TDR   

116: Exposing the distinctive modular behavior of β-strands and α-helices in folded proteins.
Wang H, Logan DT, Danielsson J, Oliveberg M.
Proc Natl Acad Sci U S A. (2020 Nov) 117:28775-28783
DOI: 10.1073/pnas.1920455117  |   PUBMED: 33148805  |   IF(2019) = 9.4
PDB [P14]:  6I6E  6I69  6I6I  6I6O   

115: Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38.
Kirsch K, Zeke A, Tőke O, Sok P, Sethi A, Sebő A, Kumar GS, Egri P, Póti ÁL, Gooley P, Peti W, Bento I, Alexa A, Reményi A.
Nat Commun. (2020 Nov)11:5769
DOI: 10.1038/s41467-020-19582-3  |   PUBMED: 33188182  |   IF(2022) = 14.9
PDB [P14]:  6ZQS  6ZR5   

114: Structural role of essential light chains in the apicomplexan glideosome.
Pazicky S, Dhamotharan K, Kaszuba K, Mertens HDT, Gilberger T, Svergun D, Kosinski J, Weininger U, Löw C.
Commun Biol. (2020 Oct)3:568
DOI: 10.1038/s42003-020-01283-8  |   PUBMED: 33051581  |   IF(2019) = 12.1
PDB [P13]:  6ZN3  6TJ4  6TJ5  6TJ6  6TJ7   

113: Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein.
Manav MC, Van LB, Lin J, Fuglsang A, Peng X, Brodersen DE.
Nat Commun. (2020 Nov)11:5993
DOI: 10.1038/s41467-020-19847-x  |   PUBMED: 33239638  |   IF(2022) = 14.9
PDB [P14]:  6THH   

112: Engineered SAM synthetases for enzymatic generation of AdoMet analogs with photocaging groups and reversible DNA modification in cascade reactions.
Michailidou F, Klöcker N, Cornelissen N, Singh RK, Peters A, Ovcharenko A, Kümmel D, Rentmeister A.
Angew Chem Int Ed Engl. (2020 Oct)UNK:pp. UNK
DOI: 10.1002/anie.202012623  |   PUBMED: 33017502  |   IF(2019) = 13.0
PDB [P13]:  6LTV  6LTW   

111: Anomeric Selectivity of Trehalose Transferase with Rare l-Sugars.
Mestrom L, Marsden SR, van der Eijk H, Laustsen JU, Jeffries CM, Svergun DI, Hagedoorn PL, Bento I, Hanefeld U.
ACS Catalysis. (2020 Aug)10:8835-8839
DOI: 10.1021/acscatal.0c02117  |   PUBMED: 32953231  |   IF(2018) = 12.1
PDB [P13]:  6ZJ4  6ZJ7  6ZMZ  6ZJH  6ZN1   

110: Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers.
Mokrushina YA, Golovin AV, Smirnov IV, Chatziefthimiou SD, Stepanova AV, Bobik TV, Zalevsky AO, Zlobin AS, Konovalov KA, Terekhov SS, Stepanov AV, Pipiya SO, Shamborant OG, Round E, Belogurov AA, Bourenkov G, Makarov AA, Wilmanns M, Xie J, Blackburn GM, Gabibov AG, Lerner RA.
Proc Natl Acad Sci U S A. (2020 Aug) UNK:pp. UNK
DOI: 10.1073/pnas.2010317117  |   PUBMED: 32859757  |   IF(2019) = 9.4
PDB [P14]:  6Y49  6Y1M  6Y1K  6Y1L   

109: Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A.
Fiebig T, Cramer JT, Bethe A, Baruch P, Curth U, Führing JI, Buettner FFR, Vogel U, Schubert M, Fedorov R, Mühlenhoff M.
Nat Commun. (2020 Sep)11:4723
DOI: 10.1038/s41467-020-18464-y  |   PUBMED: 32948778  |   IF(2022) = 14.9
PDB [P14]:  6YUS  6YUQ   

108: The Human LL-37(17-29) antimicrobial peptide reveals a functional supramolecular structure.
Engelberg Y, Landau M
Nat Commun. (2020 Aug 4) 11(1):3894.
DOI: 10.1038/s41467-020-17736-x  |   PUBMED: 32753597  |   IF(2022) = 14.9
PDB [P14]:  6S6M   

107: Sjogren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells.
Perdreau-Dahl H, Progida C, Barfeld SJ, Guldsten H, Thiede B, Arntzen M, Bakke O, Mills IG, Krauss S, Morth JP
Commun Biol. (2020 Mar 13) 3(1):123.
DOI: 10.1038/s42003-020-0851-2  |   PUBMED: 32170109  |   IF(2019) = 12.1
PDB [P13]:  6HCZ   

106: Molecular mechanism of light-driven sodium pumping.
Kovalev K, Astashkin R, Gushchin I, Orekhov P, Volkov D, Zinovev E, Marin E, Rulev M, Alekseev A, Royant A, Carpentier P, Vaganova S, Zabelskii D, Baeken C, Sergeev I, Balandin T, Bourenkov G, Carpena X, Boer R, Maliar N, Borshchevskiy V, Buldt G, Bamberg E, Gordeliy V
Nat Commun. (2020 May 1) 11(1):2137.
DOI: 10.1038/s41467-020-16032-y  |   PUBMED: 32358514  |   IF(2022) = 14.9
PDB [P14]:  6YC2  6YC3  6YC4   

105: Architecture and functional dynamics of the pentafunctional AROM complex.
Arora Veraszto H, Logotheti M, Albrecht R, Leitner A, Zhu H, Hartmann MD,
Nat Chem Biol. 2020 Jul 6.
DOI: 10.1038/s41589-020-0587-9  |   PUBMED: 32632294  |   IF(2020) = 41.8
PDB [P14]:  6HQV   

104: Crystal structure and interactions of the Tof1-Csm3 (Timeless-Tipin) fork protection complex.
Grabarczyk DB,
Nucleic Acids Res. 2020 Jul 9;48(12):6996-7004.
DOI: 10.1093/nar/gkaa456  |   PUBMED: 32469068  |   IF(2018) = 11.1
PDB [P14]:  6XWX   

103: Human REXO2 controls short mitochondrial RNAs generated by mtRNA processing and decay machinery to prevent accumulation of double-stranded RNA.
Szewczyk M, Malik D, Borowski LS, Czarnomska SD, Kotrys AV, Klosowska-Kosicka K, Nowotny M, Szczesny RJ,
Nucleic Acids Res. 2020 Jun 4;48(10):5572-5590.
DOI: 10.1093/nar/gkaa302  |   PUBMED: 32365187  |   IF(2018) = 11.1
PDB [P13]:  6STY   

102: Structural basis for antibiotic action of the B1 antivitamin 2'-methoxy-thiamine.
Rabe von Pappenheim F, Aldeghi M, Shome B, Begley T, de Groot BL, Tittmann K.
Nat Chem Biol. (2020 Aug) UNK:pp. UNK
DOI: 10.1038/s41589-020-0628-4  |   PUBMED: 32839604  |   IF(2020) = 41.8
PDB [P14]:  6TJ8  6TJ9   

101: Structural signatures in EPR3 define a unique class of plant carbohydrate receptors.
Wong JEMM, Gysel K, Birkefeldt TG, Vinther M, Muszyński A, Azadi P, Laursen NS, Sullivan JT, Ronson CW, Stougaard J, Andersen KR.
Nat Commun. (2020 Jul)11:3797
DOI: 10.1038/s41467-020-17568-9  |   PUBMED: 32732998  |   IF(2022) = 14.9
PDB [P14]:  6QUP   

100: Structure and mechanism of CutA, RNA nucleotidyl transferase with an unusual preference for cytosine.
Malik D, Kobyłecki K, Krawczyk P, Poznański J, Jakielaszek A, Napiórkowska A, Dziembowski A, Tomecki R, Nowotny M.
Nucleic Acids Res. (2020 Aug)UNK:pp. UNK
DOI: 10.1093/nar/gkaa647  |   PUBMED: 32785623  |   IF(2018) = 11.1
PDB [P13]:  6YWN  6YWO   

99: Binding specificities of human RNA-binding proteins toward structured and linear RNA sequences.
Jolma A, Zhang J, Mondragón E, Morgunova E, Kivioja T, Laverty KU, Yin Y, Zhu F, Bourenkov G, Morris Q, Hughes TR, Maher LJ, Taipale J.
Genome Res. 2020 Julpp. UNK
DOI: DOI: 10.1101/gr.258848.119  |   PUBMED: 32703884  |   IF(2019) = 9.9
PDB [P13]:  6SJD   

98: A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding.
Terekhov SS, Mokrushina YA, Nazarov AS, Zlobin A, Zalevsky A, Bourenkov G, Golovin A, Belogurov A, Osterman IA, Kulikova AA, Mitkevich VA, Lou HJ, Turk BE, Wilmanns M, Smirnov IV, Altman S, Gabibov AG.
Sci Adv. 2020 6(26):eaaz9861
DOI: 10.1126/sciadv.aaz9861  |   PUBMED: 32637600  |   IF(2018) = 12.5
PDB [P13]:  6SUI  6SV5  6SUM  6SUL  6SUN   

97: Structural and functional characterization of the severe fever withthrombocytopenia syndrome virus L protein.
Vogel D, Thorkelsson SR, Quemin ERJ, Meier K, Kouba T, Gogrefe N, Busch C, Reindl S, Gunther S, Cusack S, Grunewald K, Rosenthal M
Nucleic Acids Res. 2020 Jun 4;48(10):5749-5765.
DOI: 10.1093/nar/gkaa253  |   PUBMED: 32313945  |   IF(2018) = 11.1
PDB [P14]:  6XYA   

96: Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Singh K, Graf B, Linden A, Sautner V, Urlaub H, Tittmann K, Stark H, Chari A
Cell. 2020 Mar 19;180(6):1130-1143.e20.
DOI: 10.1016/j.cell.2020.02.034  |   PUBMED: 32160528  |   IF(2018) = 36.2
PDB [P14]:  6QL9  6QL7   

95: Identification of targets of AMPylating Fic enzymes by co-substrate-mediated covalent capture.
Gulen B, Rosselin M, Fauser J, Albers MF, Pett C, Krisp C, Pogenberg V, Schlüter H, Hedberg C, Itzen A.
Nat Chem. (2020 Aug)12:732-739
DOI: 10.1038/s41557-020-0484-6  |   PUBMED: 32632184  |   IF(2019) = 21.7
PDB [P13]:  6SIU   

94: Loss of GFAT-1 feedback regulation activates the hexosamine pathway thatmodulates protein homeostasis.
Ruegenberg S, Horn M, Pichlo C, Allmeroth K, Baumann U, Denzel MS,
Nat Commun. 2020 Feb 4;11(1):687.
DOI: 10.1038/s41467-020-14524-5  |   PUBMED: 32019926  |   IF(2022) = 14.9
PDB [P13]:  6SVO   

93: Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Hamann F, Schmitt A, Favretto F, Hofele R, Neumann P, Xiang S, Urlaub H, Zweckstetter M, Ficner R,
Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):2948-2956.
DOI: 10.1073/pnas.1907960117  |   PUBMED: 31974312  |   IF(2019) = 9.4
PDB [P13]:  6R4E  6RM8  6RMC  6RMB  6RMA  6RM9   

92: p63 uses a switch-like mechanism to set the threshold for induction of apoptosis.
Gebel J, Tuppi M, Chaikuad A, Hotte K, Schroder M, Schulz L, Lohr F, Gutfreund N, Finke F, Henrich E, Mezhyrova J, Lehnert R, Pampaloni F, Hummer G, Stelzer EHK, Knapp S, Dotsch V,
Nat Chem Biol. 2020 Jul 27. pii: 10.1038/s41589-020-0600-3. doi:10.1038/s41589-020-0600-3.
DOI: 10.1038/s41589-020-0600-3 [doi]  |   PUBMED: 32719556  |   IF(2020) = 41.8
PDB [P13]:  6RU6   

91: The structural basis of fungal glucuronoyl esterase activity on natural substrates.
Ernst HA, Mosbech C, Langkilde AE, Westh P, Meyer AS, Agger JW, Larsen S
Nat Commun. 2020 Feb 24;11(1):1026.
DOI: 10.1038/S41467-020-14833-9  |   PUBMED: 32094331  |   IF(2022) = 14.9
PDB [P13]:  6RU1   

Number of publications for 2020: 32


2019


90: Increased versatility despite reduced molecular complexity: evolution, structure and function of metazoan splicing factor PRPF39.
De Bortoli F, Neumann A, Kotte A, Timmermann B, Schuler T, Wahl MC, Loll B, Heyd F,
Nucleic Acids Res. 2019 Jun 20;47(11):5867-5879.
DOI: 10.1093/nar/gkz243  |   PUBMED: 30949712  |   IF(2018) = 11.1
PDB [P14]:   

89: Molecular adaptations of NADP-malic enzyme for its function in C4 photosynthesis in grasses.
Alvarez CE, Bovdilova A, Hoppner A, Wolff CC, Saigo M, Trajtenberg F, Zhang T, Buschiazzo A, Nagel-Steger L, Drincovich MF, Lercher MJ, Maurino VG,
Nat Plants. 2019 Jul;5(7):755-765. Epub 2019 Jun 24.
DOI: 10.1038/s41477-019-0451-7  |   PUBMED: 31235877  |   IF(2019) = 13.3
PDB [P13]:   

88: Mechanism for antigenic peptide selection by endoplasmic reticulum aminopeptidase 1.
Giastas P, Mpakali A, Papakyriakou A, Lelis A, Kokkala P, Neu M, Rowland P, Liddle J, Georgiadis D, Stratikos
Proc Natl Acad Sci U S A. 2019 Dec
DOI: 10.1073/pnas.1912070116  |   PUBMED: 31843903  |   IF(2019) = 9.4
PDB [P13]:  6RYF  6RQX   

87: Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes.
Grimm C, Hillen HS, Bedenk K, Bartuli J, Neyer S, Zhang Q, Huttenhofer A, Erlacher M, Dienemann C, Schlosser A, Urlaub H, Bottcher B, Szalay AA, Cramer P, Fischer U
Cell. 2019 Dec 12;179(7):1537-1550.e19.
DOI: 10.1016/j.cell.2019.11.024  |   PUBMED: 31835032  |   IF(2018) = 36.2
PDB [P13]:  6RFG   

86: The Structure of the Elusive Urease-Urea Complex Unveils the Mechanism of a Paradigmatic Nickel-Dependent Enzyme.
Mazzei L, Cianci M, Benini S, Ciurli S,
Angew Chem Int Ed Engl. 2019 May 27;58(22):7415-7419. Epub 2019 Apr 30.
DOI: 10.1002/ANIE.201903565  |   PUBMED: 30969470  |   IF(2019) = 13.0
PDB [P13]:  6QDY   

85: Unique structure and function of viral rhodopsins.
Bratanov D, Kovalev K, Machtens JP, Astashkin R, Chizhov I, Soloviov D, Volkov D, Polovinkin V, Zabelskii D, Mager T, Gushchin I, Rokitskaya T, Antonenko Y, Alekseev A, Shevchenko V, Yutin N, Rosselli R, Baeken C, Borshchevskiy V, Bourenkov G, Popov A, Balandin T, Buldt G, Manstein DJ, Rodriguez-Valera F, Fahlke C, Bamberg E, Koonin E, Gordeliy V,
Nat Commun. 2019 Oct 30;10(1):4939.
DOI: 10.1038/S41467-019-12718-0  |   PUBMED: 31666521  |   IF(2022) = 14.9
PDB [P14]:  6SQG  6XYT   

84: Molecular features of the UNC-45 chaperone critical for binding and foldingmuscle myosin.
Hellerschmied D, Lehner A, Franicevic N, Arnese R, Johnson C, Vogel A, Meinhart A, Kurzbauer R, Deszcz L, Gazda L, Geeves M, Clausen T
Nat Commun. 2019 Oct 21;10(1):4781.
DOI: 10.1038/S41467-019-12667-8  |   PUBMED: 31636255  |   IF(2022) = 14.9
PDB [P13]:  6QDJ   

83: Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Slyvka A, Zagorskaite E, Czapinska H, Sasnauskas G, Bochtler M,
Nucleic Acids Res. 2019 Nov 14.
DOI: 10.1093/nar/gkz1017  |   PUBMED: 31724709   |   IF(2018) = 11.1
PDB [P14]:  6T22  6T21   

82: Liquid application method for time-resolved analyses by serial synchrotron crystallography.
Mehrabi P, Schulz EC, Agthe M, Horrell S, Bourenkov G, von Stetten D, Leimkohl JP, Schikora H, Schneider TR, Pearson AR, Tellkamp F, Miller RJD
Nat Methods. 2019 Oct;16(10):979-982. Epub 2019Sep 16.
DOI: 10.1038/S41592-019-0553-1  |   PUBMED: 31527838  |   IF(2018) = 28.5
PDB [P14]:  6RNC  6RNB  6RND  6RNF  6QNJ  6QNH  6QNI  6QND  6QNB  6QNC   

81: Marine Proteobacteria metabolize glycolate via the beta-hydroxyaspartate cycle.
Schada von Borzyskowski L, Severi F, Kruger K, Hermann L, Gilardet A, Sippel F, Pommerenke B, Claus P, Cortina NS, Glatter T, Zauner S, Zarzycki J, Fuchs BM, Bremer E, Maier UG, Amann RI, Erb TJ,
Nature. 2019 Nov;575(7783):500-504. Epub 2019 Nov13.
DOI: 10.1038/s41586-019-1748-4  |   PUBMED: 31723261  |   IF(2018) = 43.1
PDB [P13]:  6RQA   

80: High-throughput peptide-MHC complex generation and kinetic screenings of TCRswith peptide-receptive HLA-A*02:01 molecules.
Moritz A, Anjanappa R, Wagner C, Bunk S, Hofmann M, Pszolla G, Saikia A, Garcia-Alai M, Meijers R, Rammensee HG, Springer S, Maurer D,
Sci Immunol. 2019 Jul 19;4(37).
DOI: 10.1126/sciimmunol.aav0860  |   PUBMED: 31324691  |   IF(2018) = 10.5
PDB [P13]:  6Q3K  6Q3S   

79: Structural insights into synthetic ligands targeting A-A pairs in disease-relatedCAG RNA repeats.
Mukherjee S, Blaszczyk L, Rypniewski W, Falschlunger C, Micura R, Murata A, Dohno C, Nakatani K, Kiliszek A,
Nucleic Acids Res. 2019 Nov 18;47(20):10906-10913.
DOI: 10.1093/nar/gkz832  |   PUBMED: 31566242  |   IF(2018) = 11.1
PDB [P13]:  6QIQ   

78: Low-barrier hydrogen bonds in enzyme cooperativity.
Dai S, Funk LM, von Pappenheim FR, Sautner V, Paulikat M, Schroder B, Uranga J, Mata RA, Tittmann K,
Nature. 2019 Sep 18.
DOI: 10.1038/s41586-019-1581-9  |   PUBMED: 31534226  |   IF(2018) = 43.1
PDB [P13P14]:  6HAD  6HA3  6RJB  6RJC  6HAF   

77: Time-resolved crystallography reveals allosteric communication aligned withmolecular breathing.
Mehrabi P, Schulz EC, Dsouza R, Muller-Werkmeister HM, Tellkamp F, Miller RJD, Pai EF,
Science. 2019 Sep 13;365(6458):1167-1170.
DOI: 10.1126/SCIENCE.AAW9904  |   PUBMED: 31515393  |   IF(2018) = 41.1
PDB [P14]:  6QI1  6QHY  6QHX   

76: Structure of the plastic-degrading Ideonella sakaiensis MHETase bound to asubstrate.
Palm GJ, Reisky L, Bottcher D, Muller H, Michels EAP, Walczak MC, Berndt L, Weiss MS, Bornscheuer UT, Weber G,
Nat Commun. 2019 Apr 12;10(1):1717.
DOI: 10.1038/S41467-019-09326-3  |   PUBMED: 30979881  |   IF(2022) = 14.9
PDB [P13]:  6QGC   

75: (p)ppGpp Regulates a Bacterial Nucleosidase by an Allosteric Two-Domain Switch.
Zhang YE, Baerentsen RL, Fuhrer T, Sauer U, Gerdes K, Brodersen DE,
Mol Cell. 2019 Apr 16.
DOI: 10.1016/J.MOLCEL.2019.03.035  |   PUBMED: 31023582  |   IF(2018) = 14.5
PDB [P13]:  6GFM   

74: Protein crystallization promotes type 2 immunity and is reversible by antibodytreatment.
Persson EK, Verstraete K, Heyndrickx I, Gevaert E, Aegerter H, Percier JM, Deswarte K, Verschueren KHG, Dansercoer A, Gras D, Chanez P, Bachert C, Goncalves A, Van Gorp H, De Haard H, Blanchetot C, Saunders M, Hammad H, Savvides SN, Lambrecht BN,
Science. 2019 May 24;364(6442).
DOI: 10.1126/SCIENCE.AAW4295  |   PUBMED: 31123109  |   IF(2018) = 41.1
PDB [P14]:  6QRN  6GKS  6GKQ   

73: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebscycle.
Verschueren KHG, Blanchet C, Felix J, Dansercoer A, De Vos D, Bloch Y, Van Beeumen J, Svergun D, Gutsche I, Savvides SN, Verstraete K,
Nature. 2019 Apr 3.
DOI: 10.1038/S41586-019-1095-5  |   PUBMED: 30944476  |   IF(2018) = 43.1
PDB [P13P14]:  6HXK  6QCL  6QFB   

72: Structural basis for RNA translocation by DEAH-box ATPases.
Hamann F, Enders M, Ficner R,
Nucleic Acids Res. 2019 Mar 4.
DOI: 10.1093/NAR/GKZ150  |   PUBMED: 30828714  |   IF(2018) = 11.1
PDB [P13]:  6I3O  6QIE  6QIC  6I3P   

71: An NAD(+) Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Svergun DI, Schnappinger D, Schneider TR, Genevaux P, de Carvalho LPS, Wilmanns M, Parret AHA, Neyrolles O,
Mol Cell. 2019 Mar 21;73(6):1282-1291.e8. Epub2019 Feb 18.
DOI: 10.1016/j.molcel.2019.01.028  |   PUBMED: 30792174  |   IF(2018) = 14.5
PDB [P13]:  6FKG   

70: Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Cruz-Migoni A, Canning P, Quevedo CE, Bataille CJR, Bery N, Miller A, Russell AJ, Phillips SEV, Carr SB, Rabbitts TH,
Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2545-2550. Epub 2019 Jan 25.
DOI: 10.1073/PNAS.1811360116  |   PUBMED: 30683716  |   IF(2019) = 9.4
PDB [P14]:  6GQW  6GQY  6GQX   

69: Structure of Prototypic Peptide Transporter DtpA from E. coli in Complex with Valganciclovir Provides Insights into Drug Binding of Human PepT1.
Ural-Blimke Y, Flayhan A, Strauss J, Rantos V, Bartels K, Nielsen R, Pardon E, Steyaert J, Kosinski J, Quistgaard EM, Low C,
J Am Chem Soc. 2019 Jan 31.
DOI: 10.1021/JACS.8B11343  |   PUBMED: 30644743  |   IF(2018) = 14.7
PDB [P13]:  6GS4  6GS7   

Number of publications for 2019: 22


2018


68: Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMalpha peptides.
Salinas N, Colletier JP, Moshe A, Landau M
Nat Commun. 2018 Aug 29;9(1):3512.
DOI: 10.1038/s41467-018-05490-0  |   PUBMED: 30158633  |   IF(2022) = 14.9
PDB [P14]:  6FHD   

67: The cost of long catalytic loops in folding and stability of the ALS-associatedprotein SOD1.
Yang F, Wang H, Logan DT, Mu X, Danielsson J, Oliveberg M,
J Am Chem Soc. 2018 Oct 25.
DOI: 10.1021/JACS.8B08141  |   PUBMED: 30359015  |   IF(2018) = 14.7
PDB [P14]:  6FLH   

66: The hit-and-return system enables efficient time-resolved serial synchrotron crystallography.
Schulz EC, Mehrabi P, Muller-Werkmeister HM, Tellkamp F, Jha A, Stuart W, Persch E, De Gasparo R, Diederich F, Pai EF, Miller RJD,
Nat Methods. 2018 Nov;15(11):901-904. Epub 2018Oct 30.
DOI: 10.1038/S41592-018-0180-2  |   PUBMED: 30377366  |   IF(2018) = 28.5
PDB [P14]:  6FSX  6GXH  6GXT   

65: Crystal structure of human mARC1 reveals its exceptional position amongeukaryotic molybdenum enzymes.
Kubitza C, Bittner F, Ginsel C, Havemeyer A, Clement B, Scheidig AJ, ORCID: 0000-0002-2382-8818,
Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):11958-11963. Epub 2018 Nov 5.
DOI: 10.1073/pnas.1808576115  |   PUBMED: 30397129  |   IF(2019) = 9.4
PDB [P14]:  6FW2   

64: Towards a comprehensive understanding of the structural dynamics of a bacterialditerpene synthase during catalysis.
Driller R, Janke S, Fuchs M, Warner E, Mhashal AR, Major DT, Christmann M, Bruck T, Loll B
Nat Commun. 2018 Sep 28;9(1):3971.
DOI: 10.1038/S41467-018-06325-8  |   PUBMED: 30266969  |   IF(2022) = 14.9
PDB [P14]:  6GGL   

63: Intriguing role of water in protein-ligand binding studied by neutroncrystallography on trypsin complexes.
Schiebel J, Gaspari R, Wulsdorf T, Ngo K, Sohn C, Schrader TE, Cavalli A, Ostermann A, Heine A, Klebe G
Nat Commun. 2018 Sep 3;9(1):3559.
DOI: 10.1038/s41467-018-05769-2  |   PUBMED: 30177695  |   IF(2022) = 14.9
PDB [P14]:  5MNE  5MNN  5MNG  5MNQ  5MNF  5MNH  5MOP  5MOQ  5MOS   

62: Activity and structure of EcoKMcrA.
Czapinska H, Kowalska M, Zagorskaite E, Manakova E, Slyvka A, Xu SY, Siksnys V, Sasnauskas G, Bochtler M,
Nucleic Acids Res. 2018 Aug 10.
DOI: 10.1093/nar/gky731.  |   PUBMED: 30107581  |   IF(2018) = 11.1
PDB [P13]:  5OJH  6GHC   

61: Structural and functional insights into the unique CBS-CP12 fusion protein familyin cyanobacteria.
Hackenberg C, Hakanpaa J, Cai F, Antonyuk S, Eigner C, Meissner S, Laitaoja M, Janis J, Kerfeld CA, Dittmann E, Lamzin VS,
Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7141-7146. Epub 2018 Jun 18.
DOI: 10.1073/pnas.1806668115  |   PUBMED: 29915055  |   IF(2019) = 9.4
PDB [P13]:  5NPL  5NVD  5NMU   

60: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Schmidt K, Gardill BR, Kern A, Kirchweger P, Borsch M, Muller YA,
Proc Natl Acad Sci U S A. 2018 May 14.
DOI: 10.1073/PNAS.1716666115  |   PUBMED: 29760101  |   IF(2019) = 9.4
PDB [P14]:  5OM3  5OM5   

59: p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage.
Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA, Beli P
Nat Commun. 2018 Mar 9;9(1):1017.
DOI: 10.1107/S1600576717014479  |   PUBMED: 29523821  |   IF(2022) = 14.9
PDB [P14]:  6EIH   

58: Structural basis of DNA target recognition by the B3 domain of Arabidopsisepigenome reader VAL1.
Sasnauskas G, Kauneckaite K, Siksnys V
Nucleic Acids Res. 2018 Apr 6.
DOI: 10.1093/NAR/GKY256  |   PUBMED: 29660015  |   IF(2018) = 11.1
PDB [P14]:  6FAS   

57: The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1helicase-like motor.
Toliusis P, Tamulaitiene G, Grigaitis R, Tuminauskaite D, Silanskas A, Manakova E, Venclovas C, Szczelkun MD, Siksnys V, Zaremba M,
Nucleic Acids Res. 2018 Mar 16;46(5):2560-2572.
DOI: 10.1093/NAR/GKY107  |   PUBMED: 29471489  |   IF(2018) = 11.1
PDB [P14]:  6F1S   

56: A family of unconventional deubiquitinases with modular chain specificitydeterminants.
Hermanns T, Pichlo C, Woiwode I, Klopffleisch K, Witting KF, Ovaa H, Baumann U, Hofmann K
Nat Commun. 2018 Feb 23;9(1):799.
DOI: 10.1038/S41467-018-03148-5  |   PUBMED: 29476094  |   IF(2022) = 14.9
PDB [P13]:  6EI1   

55: Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1through DCC.
Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang JH, Meijers R
Neuron. 2018 Mar 21;97(6):1261-1267.e4. Epub2018 Mar 1.
DOI: 10.1016/J.NEURON.2018.02.010  |   PUBMED: 29503192  |   IF(2018) = 14.4
PDB [P14]:  6FKQ   

54: Epsin and Sla2 form assemblies through phospholipid interfaces.
Garcia-Alai MM, Heidemann J, Skruzny M, Gieras A, Mertens HDT, Svergun DI, Kaksonen M, Uetrecht C, Meijers R
Nat Commun. 2018 Jan 23;9(1):328.
DOI: 10.1038/S41467-017-02443-X  |   PUBMED: 29362354  |   IF(2022) = 14.9
PDB [P14]:  6ENR  5ONF  5ON7   

53: Transposase-DNA Complex Structures Reveal Mechanisms for ConjugativeTransposition of Antibiotic Resistance.
Rubio-Cosials A, Schulz EC, Lambertsen L, Smyshlyaev G, Rojas-Cordova C, Forslund K, Karaca E, Bebel A, Bork P, Barabas O
Cell. 2018 Mar 22;173(1):208-220.e20. Epub 2018 Mar 15.
DOI: 10.1016/J.CELL.2018.02.032  |   PUBMED: 29551265  |   IF(2018) = 36.2
PDB [P13]:  6EN1  6EN2  6EN0  6EMY  6EMZ   

52: Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Petrova OA, Mantsyzov AB, Rodina EV, Efimov SV, Hackenberg C, Hakanpää J, Klochkov VV, Lebedev AA, Chugunova AA, Malyavko AN, Zatsepin TS, Mishin AV, Zvereva MI, Lamzin VS, Dontsova OA, Polshakov VI.
Nucleic Acids Res. (2018 Feb)46:1525-1540
DOI: 10.1093/nar/gkx1275  |   PUBMED: 29294091  |   IF(2018) = 11.1
PDB [P13]:  5NPT   

51: Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23Receptor Enables Recruitment of the Shared Receptor IL-12Rbeta1.
Bloch Y, Bouchareychas L, Merceron R, Skladanowska K, Van den Bossche L, Detry S, Govindarajan S, Elewaut D, Haerynck F, Dullaers M, Adamopoulos IE, Savvides SN
Immunity. 2018 Jan 16;48(1):45-58.e6. Epub2017 Dec 26.
DOI: 10.1016/J.IMMUNI.2017.12.008  |   PUBMED: 29287995  |   IF(2018) = 21.5
PDB [P14]:  5NJD  5MXA  5MZV  5M85   

50: Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity.
Dolot R, Lam CH, Sierant M, Zhao Q, Liu FW, Nawrot B, Egli M, Yang X
Nucleic Acids Res. 2018 May 18;46(9):4819-4830.
DOI: 10.1093/nar/gky268.  |   PUBMED: 29684204  |   IF(2018) = 11.1
PDB [P13]:  6EO6   

Number of publications for 2018: 19


2017


49: Molecular basis of the 14-3-3 protein-dependent activation of yeast neutraltrehalase Nth1.
Alblova M, Smidova A, Docekal V, Vesely J, Herman P, Obsilova V, Obsil T,
Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):E9811-E9820. Epub 2017 Oct 30.
DOI: 10.1073/PNAS.1714491114  |   PUBMED: 29087344  |   IF(2019) = 9.4
PDB [P13]:  5JTA   

48: Mechanism of RNA polymerase II stalling by DNA alkylation
Malvezzi S, Farnung L, Aloisi CMN, Angelov T, Cramer P, Sturla SJ
Proc Natl Acad Sci U S A. 2017 Oct 30.
DOI: 10.1073/PNAS.1706592114  |   PUBMED: 29087308   |   IF(2019) = 9.4
PDB [P13]:  5OT2   

47: UbaLAI is a monomeric Type IIE restriction enzyme.
Sasnauskas G, Tamulaitiene G, Tamulaitis G, Calyseva J, Laime M, Rimseliene R, Lubys A, Siksnys V,
Nucleic Acids Res. 2017 Sep 19;45(16):9583-9594.
DOI: 10.1093/NAR/GKX634  |   PUBMED: 28934493  |   IF(2018) = 11.1
PDB [P13]:  5O63   

46: Mechanism of Transcription Anti-termination in Human Mitochondria.
Hillen HS, Parshin AV, Agaronyan K, Morozov YI, Graber JJ, Chernev A, Schwinghammer K, Urlaub H, Anikin M, Cramer P, Temiakov D,
Cell. 2017 Oct 7.
DOI: 10.1016/J.CELL.2017.09.035  |   PUBMED: 29033127   |   IF(2018) = 36.2
PDB [P13]:  5OL9   

45: Structural Basis for Mitotic Centrosome Assembly in Flies.
Feng Z, Caballe A, Wainman A, Johnson S, Haensele AFM, Cottee MA, Conduit PT, Lea SM, Raff JW,
Cell. 2017 Jun 1;169(6):1078-1089.e13.
DOI: 10.1016/J.CELL.2017.05.030  |   PUBMED: 28575671  |   IF(2018) = 36.2
PDB [P13]:  5MW9  5MW0   

44: Charges Shift Protonation: Neutron Diffraction Reveals that Aniline and2-Aminopyridine Become Protonated Upon Binding to Trypsin.
Schiebel J, Gaspari R, Sandner A, Ngo K, Gerber HD, Cavalli A, Ostermann A, Heine A, Klebe G
Angew Chem Int Ed Engl. 2017 Apr 18;56(17):4887-4890. Epub 2017 Mar 28.
DOI: 10.1002/ANIE.201701038  |   PUBMED: 28371253  |   IF(2019) = 13.0
PDB [P14]:  5MN1  5MNC  5MNB  5MON   

43: Core Mediator structure at 3.4 A extends model of transcription initiationcomplex.
Nozawa K, Schneider TR, Cramer P,
Nature. 2017 May 11;545(7653):248-251.
DOI: 10.1038/NATURE22328  |   PUBMED: 28467824  |   IF(2018) = 43.1
PDB [P14]:  5N9J   

42: EXPLAINING OPERATIONAL INSTABILITY OF AMINE TRANSAMINASES: SUBSTRATE-INDUCED INACTIVATION MECHANISM AND INFLUENCE OF QUATERNARY STRUCTURE ON ENZYME-COFACTOR INTERMEDIATE STABILITY.
T.BORNER,S.RAMISCH,E.REDDEM,S.BARTSCH,A.VOGEL, A.M.W.H.THUNNISSEN,P.ADLERCREUTZ,C.GREY
ACS Catalysis. 7:1259-1269 (2017)
DOI: 10.1021/ACSCATAL.6B02100  |   PUBMED:   |   IF(2018) = 12.1
PDB [P14]:  5LH9   

41: Structural and functional innovations in the real-time evolution of new(betaalpha)8 barrel enzymes.
Newton MS, Guo X, Soderholm A, Nasvall J, Lundstrom P, Andersson DI, Selmer M, Patrick WM
Proc Natl Acad Sci U S A. 2017 May 2;114(18):4727-4732. Epub 2017 Apr 17.
DOI: 10.1073/PNAS.1618552114  |   PUBMED: 28416687  |   IF(2019) = 9.4
PDB [P14]:  5L6U   

40: Functional and structural insight into properdin control of complement alternative pathway amplification.
Pedersen DV, Roumenina L, Jensen RK, Gadeberg TA, Marinozzi C, Picard C, Rybkine T, Thiel S, Sørensen UB, Stover C, Fremeaux-Bacchi V, Andersen GR.
EMBO J. 2017 Apr 13;36(8):1084-1099.
DOI: 10.15252/embj.201696173. Epub 2017 Mar 6.  |   PUBMED: 28264884   |   IF(2018) = 11.2
PDB [P14]:  PDB:   

39: Evaluating the Contribution of Transition-State Destabilization to Changes in theResidence Time of Triazole-Based InhA Inhibitors.
Spagnuolo LA, Eltschkner S, Yu W, Daryaee F, Davoodi S, Knudson SE, Allen EK, Merino J, Pschibul A, Moree B, Thivalapill N, Truglio JJ, Salafsky J, Slayden RA, Kisker C, Tonge PJ,
J Am Chem Soc. 2017 Feb 22.
DOI: 10.1021/JACS.6B11148  |   PUBMED: 28151657  |   IF(2015) = 13.0
PDB [P13]:  5MTQ   

38: Architecture and mechanism of the late endosomal Rab7-like Ypt7 guaninenucleotide exchange factor complex Mon1-Ccz1.
Kiontke S, Langemeyer L, Kuhlee A, Schuback S, Raunser S, Ungermann C, Kummel D,
Nat Commun. 2017 Jan 4;8:14034.
DOI: 10.1038/NCOMMS14034  |   PUBMED: 28051187  |   IF(2015) = 11.3
PDB [P13]:  5LDD   

37: Small Molecule Microarray Based Discovery of PARP14 Inhibitors.
Peng B, Thorsell AG, Karlberg T, Schuler H, Yao SQ,
Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253. Epub 2016 Dec 5.
DOI: 10.1002/ANIE.201609655  |   PUBMED: 27918638  |   IF(2015) = 11.7
PDB [P13]:  5LYH   

Number of publications for 2017: 13


2016


36: Structural basis of myelin-associated glycoprotein adhesion and signalling.
Pronker MF, Lemstra S, Snijder J, Heck AJ, Thies-Weesie DM, Pasterkamp RJ, Janssen BJ
Nat Commun. 2016 Dec 6;7:13584.
DOI: 10.1038/NCOMMS13584  |   PUBMED: 27922006  |   IF(2022) = 14.9
PDB [P14]:  5LFU   

35: Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptorGIF.
Felix J, Kandiah E, De Munck S, Bloch Y, van Zundert GC, Pauwels K, Dansercoer A, Novanska K, Read RJ, Bonvin AM, Vergauwen B, Verstraete K, Gutsche I, Savvides SN
Nat Commun. 2016 Nov 7;7:13228.
DOI: 10.1038/NCOMMS13228  |   PUBMED: 27819269  |   IF(2015) = 11.3
PDB [P14]:  5D22  5D28   

34: Robotic QM/MM-driven maturation of antibody combining sites.
Smirnov IV, Golovin AV, Chatziefthimiou SD, Stepanova AV, Peng Y, Zolotareva OI, Belogurov AA Jr, Kurkova IN, Ponomarenko NA, Wilmanns M, Blackburn GM, Gabibov AG, Lerner RA
Sci Adv. 2016 Oct 19;2(10):e1501695. eCollection 2016 Oct.
DOI: 10.1126/SCIADV.1501695  |   PUBMED: 27774510  |   IF(2018) = 12.5
PDB [P14]:  5TJD  6Y1N  5ADO   

33: The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Schrader J, Henneberg F, Mata RA, Tittmann K, Schneider TR, Stark H, Bourenkov G, Chari A
Science. 2016 Aug 5;353(6299):594-8.
DOI: 10.1126/SCIENCE.AAF8993  |   PUBMED: 27493187  |   IF(2015) = 34.6
PDB [P14]:  5LE5  5LF1  5LF0  5LF3  5LF4  5LF6  5LF7  5LEX  5LEY  5LEZ   

32: Molecular basis for inhibition of AcrB multidrug efflux pump by novel andpowerful pyranopyridine derivatives.
Sjuts H, Vargiu AV, Kwasny SM, Nguyen ST, Kim HS, Ding X, Ornik AR, Ruggerone P, Bowlin TL, Nikaido H, Pos KM, Opperman TJ,
Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3509-14. Epub 2016 Mar 14.
DOI: 10.1073/PNAS.1602472113  |   PUBMED: 26976576  |   IF(2015) = 9.74
PDB [P13]:  5ENT   

31: Aurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidases.
Molitor C, Mauracher SG, Rompel A
Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1806-15. Epub 2016 Mar 14.
DOI: 10.1073/PNAS.1523575113  |   PUBMED: 26976571  |   IF(2015) = 9.74
PDB [P14]:  4Z0Y   

30: Sleeping Beauty transposase structure allows rational design of hyperactivevariants for genetic engineering.
Voigt F, Wiedemann L, Zuliani C, Querques I, Sebe A, Mates L, Izsvak Z, Ivics Z, Barabas O,
Nat Commun. 2016 Mar 30;7:11126.
DOI: 10.1038/NCOMMS11126  |   PUBMED: 27025571  |   IF(2014) = 11.4
PDB [P14]:  5CR4   

29: Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangementfor phosphoryl transfer.
Weisse RH, Faust A, Schmidt M, Schonheit P, Scheidig AJ
Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E519-28. Epub 2016 Jan 19.
DOI: 10.1073/PNAS.1518614113  |   PUBMED: 26787904  |   IF(2014) = 9.67
PDB [P14]:  5HBR  4YAK  4XYL  4YB8  4YBZ  4XYM   

Number of publications for 2016: 8


2015


28: The first crystal structures of RNA-PNA duplexes and a PNA-PNA duplex containing mismatches-toward anti-sense therapy against TREDs.
Kiliszek A, Banaszak K, Dauter Z, Rypniewski W
Nucleic Acids Res. 2015 Dec 29.
DOI: 10.1093/NAR/GKV1513  |   PUBMED: 26717983  |   IF(2015) = 9.12
PDB [P13]:  5EMF   

27: The terminal phycobilisome emitter, LCM: A light-harvesting pigment with aphytochrome chromophore.
Tang K, Ding WL, Hoppner A, Zhao C, Zhang L, Hontani Y, Kennis JT, Gartner W, Scheer H, Zhou M, Zhao KH
Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15880-5.
DOI: 10.1073/PNAS.1519177113  |   PUBMED: 26669441  |   IF(2014) = 9.67
PDB [P13]:  4XXI   

26: Enzymology of Pyran Ring A Formation in Salinomycin Biosynthesis.
Luhavaya H, Dias MV, Williams SR, Hong H, de Oliveira LG, Leadlay PF
Angew Chem Int Ed Engl. 2015 Sep 17.
DOI: 10.1002/ANIE.201507090  |   PUBMED: 26377145  |   IF(2019) = 13.0
PDB [P13]:  5CXO   

25: Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.
Oberthur D, Achenbach J, Gabdulkhakov A, Buchner K, Maasch C, Falke S, Rehders D, Klussmann S, Betzel C
Nat Commun. 2015 Apr 22;6:6923.
DOI: 10.1038/ncomms7923  |   PUBMED: 25901662   |   IF(2014) = 11.4
PDB [P13]:  4R8I   

24: Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.
Male G, von Appen A, Glatt S, Taylor NM, Cristovao M, Groetsch H, Beck M, Muller CW
Nat Commun. 2015 Jun 10;6:7387.
DOI: 10.1038/NCOMMS8387  |   PUBMED: 26060179  |   IF(2014) = 11.4
PDB [P14]:  5AIO   

23: Structural Elucidation of the Bispecificity of A Domains as a Basis forActivating Non-natural Amino Acids.
Kaljunen H, Schiefelbein SH, Stummer D, Kozak S, Meijers R, Christiansen G, Rentmeister A
Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8833-6.
DOI: 10.1002/ANGE.201503275  |   PUBMED: 26096082  |   IF(2014) = 11.6
PDB [P14]:  4D4I  4D4H  4D4G  4D56  4D57   

22: Tracing binding modes in hit-to-lead optimization: chameleon-like poses ofaspartic protease inhibitors.
Kuhnert M, Koster H, Bartholomaus R, Park AY, Shahim A, Heine A, Steuber H, Klebe G, Diederich WE
Angew Chem Int Ed Engl. 2015 Feb 23;54(9):2849-53.
DOI: 10.1002/ANIE.201411206  |   PUBMED: 25630461  |   IF(2014) = 11.6
PDB [P14]:  3WZ6   

21: Structure-Based Enzyme Tailoring of 5-Hydroxymethylfurfural Oxidase
Dijkman WP, Binda C, Fraaije MW, Mattevi A
ACS Catalysis. 5: 1833 (2015)
DOI: 10.1021/ACSCATAL.5B00031  |   PUBMED: NONE  |   IF(2018) = 12.1
PDB [P13]:  4UDP   

Number of publications for 2015: 8


2014


20: Crystal structure of the R-protein of the multisubunit ATP-dependent restriction endonuclease NgoAVII.
Tamulaitiene G, Silanskas A, Grazulis S, Zaremba M, Siksnys V.
Nucleic Acids Res. 2014 Dec 16;42(22):14022-30.
DOI: 10.1093/NAR/GKU1237  |   PUBMED: 25429979   |   IF(2018) = 11.1
PDB [P13]:  4RD5   

19: Structural basis of the regulatory mechanism of the plant CIPK family of protein kinases controlling ion homeostasis and abiotic stress.
Chaves-Sanjuan A, Sanchez-Barrena MJ, Gonzalez-Rubio JM, Moreno M, Ragel P, Jimenez M, Pardo JM, Martinez-Ripoll M, Quintero FJ, Albert A.
Proc Natl Acad Sci U S A. (2014) Oct 6.
DOI: 10.1073/PNAS.1407610111  |   PUBMED: 25288725   |   IF(2014) = 9.6
PDB [P13]:  4D28   

18: Kuhle B, Ficner R.
A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
EMBO J. 2014 Sep 15.
DOI: 10.15252/EMBJ.201488517  |   PUBMED: 25225612   |   IF(2013) = 10.7
PDB [P13]:  4TMV   

17: Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HD, Svergun DI, Zhang Y, Wang JH, Meijers R.
The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue.
Neuron. 2014 Aug 20;83(4):839-49
DOI: 10.1016/J.NEURON.2014.07.010  |   PUBMED: 25123307   |   IF(2013) = 16.5
PDB [P14]:  4URT   

16: Wen Y, Behiels E, Felix J, Elegheert J, Vergauwen B, Devreese B, Savvides SN.
The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence.
Nucleic Acids Res. 2014 Nov 1;42(15):10134-47
DOI: 10.1093/nar/gku665  |   PUBMED: 25056321   |   IF(2018) = 11.1
PDB [P13]:  4PU4  4PU5  4PU7  4PU8   

15: Kuhle, B., Ficner, R.
eIF5B employs a novel domain release mechanism to catalyze ribosomal subunit joining.
EMBO J. 33:1177-91 (2014).
DOI: 10.1002/embj.201387344  |   PUBMED: 24686316   |   IF(2018) = 11.2
PDB [P13]:  4N3N  4N3G  4NCL  4N3S  4NCF   

14: Mierzejewska, K., Siwek, W., Czapinska, H., Skowronek, K., Bujnicki, J.M., Bochtler, M.
Structural basis of the methylation specificity of R.DpnI.
Nucleic Acids Res. 42: 8745-8754 (2014)
DOI: 10.1093/nar/gku546  |   PUBMED: 24966351  |   IF(2018) = 11.1
PDB [P14]:  4KYW   

13: Kazrani, A.A., Kowalska, M., Czapinska, H., Bochtler, M.
Crystal structure of the 5hmC specific endonuclease PvuRts1I
Nucleic Acids Res. 2014 Mar 25. [Epub ahead of print]
DOI: 10.1093/nar/gku186  |   PUBMED: 24634440  |   IF(2018) = 11.1
PDB [P13]:  4OQ2   

12: Structural basis of the proinflammatory signaling complex mediated by TSLP
Verstraete, K, van Schie, L, Vyncke, L, Bloch, Y, Tavernier, J, Pauwels, E, Peelman, F, Savvides, SN
Nat Struct Mol Biol. 2014 Apr;21(4):375-82.
DOI: 10.1038/nsmb.2794  |   PUBMED: 24632570  |   IF(2013) = 11.6
PDB [P13]:  4NN5  4NN6  4NN7   

11: Resolving the activation site of positive regulators in plant phosphoenolpyruvate carboxylase.
Schlieper D, Förster, K, Paulus JK, Groth G
Mol Plant. 7:437-40 (2014)
DOI: 10.1093/mp/sst130  |   PUBMED: 24043710  |   IF(2019) = 10.8
PDB [P14]:  4BXC   

Number of publications for 2014: 10


2013


10: CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis.
Mastny M, Heuck A, Kurzbauer R, Heiduk A, Boisguerin P, Volkmer R, Ehrmann M, Rodrigues CD, Rudner DZ, Clausen T.
Cell. 155:647 (2013).
DOI: 10.1016/j.cell.2013.09.050  |   PUBMED: 24243021  |   IF(2018) = 36.2
PDB [P14]:  4C2G   

9: Crystal structure of the 14-subunit RNA polymerase I
Fernandez-Tornero C, Moreno-Morcillo M, Rashid UJ, Taylor NM, Ruiz FM, Gruene T, Legrand P, Steuerwald U, Mueller CW.
Nature. 502:644 (2013)
DOI: 10.1038/nature12636  |   PUBMED: 24153184  |   IF(2018) = 43.1
PDB [P14]:  4C3I   

8: Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ
Punekar AS, Liljeruhm J, Shepherd TR, Forster AC, Selmer M.
Nucleic Acids Res. 41(20):9537-48 (2013)
DOI: 10.1093/nar/gkt719  |   PUBMED: 23945937  |   IF(2018) = 11.1
PDB [P13]:  4BLW   

7: Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization.
Ariza A, Tanner SJ, Walter CT, Dent KC, Shepherd DA, Wu W, Matthews SV, Hiscox JA, Green TJ, Luo M, Elliott RM, Fooks AR, Ashcroft AE, Stonehouse NJ, Ranson NA, Barr JN, Edwards TA.
Nucleic Acids Res. 2013 41(11):5912
DOI: 10.1093/nar/gkt268  |   PUBMED: 23595147  |   IF(2018) = 11.1
PDB [P14]:  3ZLA   

6: The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry.
Jürgens MC, Vürüs J, Rautureau GJ, Shepherd DA, Pye VE, Muldoon J, Johnson CM, Ashcroft AE, Freund SM, Ferguson N.
Nat Chem Biol. 2013 Sep;9(9):540-7.
DOI: 10.1038/nchembio.1294.  |   PUBMED: 23851574  |   IF(2013) = 13.2
PDB [P14]:  3ZHF   

5: Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann C C, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner K P
Nature. 2013 498:332-337
DOI: 10.1038/nature12305  |   PUBMED: 23722159  |   IF(2014) = 41.4
PDB [P14]:  4KB6   

4: Greater efficiency of photosynthetic carbon fixation due to single amino-acid substitution.
Paulus JK, Schlieper D, Groth G.
Nat Commun. 4:1518 (2013)
DOI: 10.1038/ncomms2504  |   PUBMED: 23443546  |   IF(2013) = 10.2
PDB [P14]:  3ZGB   

3: A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors.
Malvezzi F, Litos G, Schleiffer A, Heuck A, Mechtler K, Clausen T, Westermann S.
EMBO J. 2013 Feb 6;32(3):409-23.
DOI: 10.1038/emboj.2012.356  |   PUBMED: 23334295  |   IF(2018) = 11.2
PDB [P14]:  4GEQ   

Number of publications for 2013: 8


2012


2: Structural basis for cooperativity of CRM1 export complex formation.
Monecke T, Haselbach D, VoßB, Russek A, Neumann P, Thomson E, Hurt E, Zachariae U, Stark H, Grubmüller H, Dickmanns A, Ficner R.
Proc Natl Acad Sci U S A. 2012 Dec 31. [Epub ahead of print]
DOI: 10.1073/pnas.1215214110  |   PUBMED: 23277578  |   IF(2019) = 9.4
PDB [P14]:  4HZK   

1: Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Santos KF, Jovin SM, Weber G, Pena V, Lührmann R, Wahl MC
Proc Natl Acad Sci U S A. (2012) Oct 23;109(43):17418-23. Epub 2012 Oct 8.
DOI: 10.1073/nas.1208098109  |   PUBMED: 23045696  |   IF(2019) = 9.4
PDB [P14]:  4F91