Total number of publications referencing P14 (233) : 233 [ as of 05/10/2022 ]

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233: Deamidation of the human eye lens protein γS-crystallin accelerates oxidative aging.
Norton-Baker B, Mehrabi P, Kwok AO, Roskamp KW, Rocha MA, Sprague-Piercy MA, von Stetten D, Miller RJD, Martin RW.
Structure. (2022 May)30:763-776.e4
DOI: 10.1016/j.str.2022.03.002  |   PUBMED: 35338852  |   IF(2018) = 4.9
PDB [P13P14]:  7N38  7N39  7N36  7N3A  7N3B  7N37   

232:  Cryo-EM Structure of an Atypical Proton-Coupled Peptide Transporter: Di- and Tripeptide Permease C.
Killer M, Finocchio G, Mertens HDT, Svergun DI, Pardon E, Steyaert J, Löw C.
Front Mol Biosci. 2022 Jul 11;9:917725.
DOI: 10.3389/fmolb.2022.917725  |   PUBMED: 35898305  |   IF(2022) = 4.6
PDB [13P14]:   

231: Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity.
Gao S, Sylvester K, Song L, Claff T, Jing L, Woodson M, Weiße RH, Cheng Y, Schäkel L, Petry M, Gütschow M, Schiedel AC, Sträter N, Kang D, Xu S, Toth K, Tavis J, Tollefson AE, Müller CE, Liu X, Zhan P.
J Med Chem. (2022 Sep)UNK:pp. UNK
DOI: 10.1021/acs.jmedchem.2c01146  |   PUBMED: 36107752  |   IF(2018) = 6.1
PDB [P13P14]:  8ACD  8ACL   

230: Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Zeke A, Takács T, Sok P, Németh K, Kirsch K, Egri P, Póti ÁL, Bento I, Tusnády GE, Reményi A.
Nat Commun. (2022 Sep)13:5439
DOI: 10.1038/s41467-022-32918-5  |   PUBMED: 36114179  |   IF(2022) = 14.9
PDB [P14]:  7PPL  7PPM  7PPN   

229: Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases.
Figiel M, Gapińska M, Czarnocki-Cieciura M, Zajko W, Sroka M, Skowronek K, Nowotny M.
Nucleic Acids Res. (2022 Sep)50:10026-10040
DOI: 10.1093/nar/gkac772  |   PUBMED: 36107766  |   IF(2018) = 11.1
PDB [P14]:  7R07   

228: A non-catalytic herpesviral protein reconfigures ERK-RSK signaling by targeting kinase docking systems in the host.
Alexa A, Sok P, Gross F, Albert K, Kobori E, Póti ÁL, Gógl G, Bento I, Kuang E, Taylor SS, Zhu F, Ciliberto A, Reményi A.
Nat Commun. 2022 Jan 25;13(1):472.
DOI: 10.1038/s41467-022-28109-x  |   PUBMED: 35078976  |   IF(2022) = 14.9
PDB [P14]:  7OPO  7OPM   

227: Structure of angiogenin dimer bound to double-stranded RNA.
Sievers K, Ficner R.
Acta Crystallogr F Struct Biol Commun (2022 Sep)78:330-337
DOI: 10.1107/s2053230x22008317  |   PUBMED: 36048083
PDB [P14]:  8AF0   

226: Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.
Truongvan N, Li S, Misra M, Kuhn M, Schindelin H.
Nat Commun. (2022 Aug)13:4789
DOI: 10.1038/s41467-022-32040-6  |   PUBMED: 35970836  |   IF(2022) = 14.9
PDB [P14]:  7PVN   

225: Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives.
Nogués I, Sekula B, Angelaccio S, Grzechowiak M, Tramonti A, Contestabile R, Ruszkowski M.
Plant Physiol Biochem. (2022 Jul)187:37-49
DOI: 10.1016/j.plaphy.2022.07.025  |   PUBMED: 35947902  |   IF(2019) = 3.72
PDB [P14]:  7QPE   

224: The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn2+ -binding domain essential for structural integrity and channel activity.
Sander S, Pick J, Gattkowski E, Fliegert R, Tidow H.
Protein Sci. (2022 Jun)31:e4320
DOI: 10.1002/pro.4320  |   PUBMED: 35634784  |   IF(2018) = 2.4
PDB [P14]:  7AOV  7RU7   

223: The crystal structure of the varicella-zoster Orf24-Orf27 nuclear egress complex spotlights multiple determinants of herpesvirus subfamily specificity.
Schweininger J, Kriegel M, Häge S, Conrad M, Alkhashrom S, Lösing J, Weiler S, Tillmanns J, Egerer-Sieber C, Decker A, Lenac Roviš T, Eichler J, Sticht H, Marschall M, Muller YA.
J Biol Chem. (2022 Mar)298:101625
DOI: 10.1016/j.jbc.2022.101625  |   PUBMED: 35074430  |   IF(2018) = 4.1
PDB [P14]:  7PAB   

222: Structural variations between small alarmone hydrolase dimers support different modes of regulation of the stringent response.
Bisiak F, Chrenková A, Zhang SD, Pedersen JN, Otzen DE, Zhang YE, Brodersen DE.
J Biol Chem. (2022 Jun)UNK:102142
DOI: 10.1016/j.jbc.2022.102142  |   PUBMED: 35714769  |   IF(2018) = 4.1
PDB [P13P14]:  7QOE  7QOC  7QOD   

221: Crystal structures of the molecular class A β-lactamase TEM-171 and its complexes with tazobactam.
Grigorenko VG, Petrova TE, Carolan C, Rubtsova MY, Uporov IV, Pereira J, Chojnowski G, Samygina VR, Lamzin VS, Egorov AM.
Acta Crystallogr D Struct Biol. (2022 Jul)78:825-834
DOI: 10.1107/s2059798322004879  |   PUBMED: 35775982  |   IF(2018) = 3.2
PDB [P14]:  7QOR   

220: Cosolvent Sites-Based Discovery of Mycobacterium Tuberculosis Protein Kinase G Inhibitors.
Burastero O, Defelipe LA, Gola G, Tateosian NL, Lopez ED, Martinena CB, Arcon JP, Traian MD, Wetzler DE, Bento I, Barril X, Ramirez J, Marti MA, Garcia-Alai MM, Turjanski AG.
J Med Chem. (2022 Jun)UNK:pp. UNK
DOI: 10.1021/acs.jmedchem.1c02012  |   PUBMED: 35737472  |   IF(2018) = 6.1
PDB [P14]:  7Q52   

219: New aspects of DNA recognition by group II WRKY transcription factor revealed by structural and functional study of AtWRKY18 DNA binding domain.
Grzechowiak M, Ruszkowska A, Sliwiak J, Urbanowicz A, Jaskolski M, Ruszkowski M.
Int J Biol Macromol. (2022 Jun)213:589-601
DOI: 10.1016/j.ijbiomac.2022.05.186  |   PUBMED: 35660042  |   IF(2018) = 4.8
PDB [P14]:  7Z0U  7Z0R   

218: Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity.
Detry S, Andries J, Bloch Y, Gabay C, Clancy DM, Savvides SN
J Biol Chem. (2022 Apr)298:101908
DOI: 10.1016/j.jbc.2022.101908  |   PUBMED: 35398099  |   IF(2018) = 4.1
PDB [-P14]:  7AL7   

217: A GH115 α-glucuronidase structure reveals dimerization-mediated substrate binding and a proton wire potentially important for catalysis.
Wilkens C, Vuillemin M, Pilgaard B, Polikarpov I, Morth JP.
Acta Crystallogr D Struct Biol. (2022 May)78:658-668
DOI: 10.1107/s2059798322003527  |   PUBMED: 35503213  |   IF(2018) = 3.2
PDB [P14]:  7PUG   

216: Family 1 Glycosyltransferase UGT706F8 from Zea mays Selectively Catalyzes the Synthesis of Silibinin 7-O-β-d-Glucoside.
Bidart GN, Putkaradze N, Fredslund F, Kjeldsen C, Ruiz AG, Duus JØ, Teze D, Welner DH.
ACS Sustain Chem Eng. (2022 Apr)10:5078-5083
DOI: 10.1021/acssuschemeng.1c07593  |   PUBMED: 35493695
PDB [P14]:  7Q3S   

215: Variability in the Spatial Structure of the Central Loop in Cobra Cytotoxins Revealed by X-ray Analysis and Molecular Modeling.
Dubovskii PV, Dubova KM, Bourenkov G, Starkov VG, Konshina AG, Efremov RG, Utkin YN, Samygina VR.
Toxins. (Basel) (2022 Feb)14:149
DOI: 10.3390/toxins14020149  |   PUBMED: 35202176
PDB [P14]:  7QFC   

214: Letter to the editor: The clinically relevant MTARC1 p.Ala165Thr variant impacts neither the fold nor active site architecture of the human mARC1 protein.
Struwe MA, Clement B, Scheidig A.
Hepatol Commun. (2022 May)UNK:pp. UNK
DOI: 10.1002/hep4.1984  |   PUBMED: 35560545
PDB [P14]:  7P41   

213: Ground-state destabilization by electrostatic repulsion is not a driving force in orotidine-5′-monophosphate decarboxylase catalysis
Rindfleisch S, Krull M, Uranga J, et al. , Tittmann K
Nat Catal. 5: 332-341 (2022)
DOI: 10.1038/s41929-022-00771-w  |   PUBMED:
PDB [P13P14]:  7AM9  6YVL  6YVM  6YVK  6YVN  7ASQ  7OQI  7OUZ  7OTU  7OQK  7OQN  7OV0  7OQM  6ZX0  6ZX1  6YVO  6YWU  6ZX3  6ZX2  6YWT  6ZWY  6ZWZ  7OQF  7Q1H   

212: The Structure of Bilirubin Oxidase from Bacillus pumilus Reveals a Unique Disulfide Bond for Site-Specific Direct Electron Transfer.
Gihaz S, Herzallh NS, Cohen Y, Bachar O, Fishman A, Yehezkeli O.
Biosensors. (Basel) (2022 Apr)12:258
DOI: 10.3390/bios12050258  |   PUBMED: 35624560
PDB [P14]:  7Z5P   

211: Rare by Natural Selection: Disulfide-Bonded Supramolecular Antimicrobial Peptides.
Engelberg Y, Ragonis-Bachar P, Landau M.
Biomacromolecules. (2022 Jan)UNK:pp. UNK
DOI: 10.1021/acs.biomac.1c01353  |   PUBMED: 35061360
PDB [P14]:  7NPQ   

210: Widespread occurrence of covalent lysine-cysteine redox switches in proteins.
Rabe von Pappenheim F, Wensien M, Ye J, Uranga J, Irisarri I, de Vries J, Funk LM, Mata RA, Tittmann K.
Nat Chem Biol. (2022 Feb)UNK:pp. UNK
DOI: 10.1038/s41589-021-00966-5  |   PUBMED: 35165445  |   IF(2020) = 41.8
PDB [P14]:  7ODO  7ODQ  7O9G  7ODP  7OEY   

209: Best practices for time-resolved serial synchrotron crystallography. o
Schulz EC, Yorke BA, Pearson AR, Mehrabi P.
Acta Crystallogr D Struct Biol. 2022;78(Pt 1):14-29.
DOI: 10.1107/S2059798321011621  |   PUBMED: 34981758  |   IF(2018) = 3.2
PDB [P14]:   

Number of publications for 2022: 25


208: Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms.
Ornik-Cha A, Wilhelm J, Kobylka J, Sjuts H, Vargiu AV, Malloci G, Reitz J, Seybert A, Frangakis AS, Pos KM.
Nat Commun. (2021 Nov)12:6919
DOI: 10.1038/s41467-021-27146-2  |   PUBMED: 34824229  |   IF(2022) = 14.9
PDB [P13P14]:  7B8R  7B8S   

207: Role of hydrogen bond alternation and charge transfer states in photoactivation of the Orange Carotenoid Protein.
Yaroshevich IA, Maksimov EG, Sluchanko NN, Zlenko DV, Stepanov AV, Slutskaya EA, Slonimskiy YB, Botnarevskii VS, Remeeva A, Gushchin I, Kovalev K, Gordeliy VI, Shelaev IV, Gostev FE, Khakhulin D, Poddubnyy VV, Gostev TS, Cherepanov DA, Polívka T, Kloz M, Friedrich T, Paschenko VZ, Nadtochenko VA, Rubin AB, Kirpichnikov MP.
Communications Biology. 2021 May;4(1):539.
DOI: 10.1038/s42003-021-02022-3.  |   PUBMED: 33972665
PDB [P14]:  6T6O  6T6M  6T6K   

206: Homogeneous batch micro-crystallization of proteins from ammonium sulfate.
Stohrer C, Horrell S, Meier S, et al.
Acta crystallographica. Section D, Structural Biology. 2021 Feb;77(Pt 2):194-204.
DOI: 10.1107/s2059798320015454.  |   PUBMED: 33559608; PMCID: PMC7869895.
PDB [P14]:   

205: Calmodulin complexes with brain and muscle creatine kinase peptides.
Sprenger J, Trifan A, Patel N, Vanderbeck A, Bredfelt J, Tajkhorshid E, Rowlett R, Lo Leggio L, Akerfeldt KS, Linse S,
Curr Res Struct Biol. 2021 May 19;3:121-132. doi: 10.1016/j.crstbi.2021.05.001.eCollection 2021.
DOI: 10.1016/j.crstbi.2021.05.001 [doi]  |   PUBMED: 34235492
PDB [P13P14]:   

204: Discovery and Characterization of the Potent and Highly Selective 1,7-Naphthyridine-Based Inhibitors BAY-091 and BAY-297 of the Kinase PIP4K2A.
Wortmann L, Bräuer N,Holton SJ, Irlbacher H, Weiske J, Lechner C, Meier R, Karén J, Siöberg CB, Pütter V, Christ CD, Ter Laak A, Lienau P, Lesche R, Nicke B, Cheung SH, Bauser M, Haegebarth A, von Nussbaum F, Mumberg D, Lemos C.
J Med Chem. 2021 Nov 11;64(21):15883-15911.
DOI: 10.1021/acs.jmedchem.1c01245.  |   PUBMED: 34699202.  |   IF(2018) = 6.1
PDB [P14]:  6YM5   

203: An automated platform for structural analysis of membrane proteins through serial crystallography.
Healey RD, Basu S, Humm AS, Leyrat C, Cong X, Golebiowski J, Dupeux F, Pica A, Granier S, Márquez JA.
Cell Rep Methods.
DOI: 10.1016/j.crmeth.2021.100102.  |   PUBMED: 34723237
PDB [P14]:  6YXD   

202: Insights into Broad-Specificity Starch Modification from the Crystal Structure of Limosilactobacillus Reuteri NCC 2613 4,6-α-Glucanotransferase GtfB.
Pijning T, Gangoiti J, Te Poele EM, Börner T, Dijkhuizen L.
J Agric Food Chem. 2021 Oct 28.
DOI: 10.1021/acs.jafc.1c05657.  |   PUBMED: 34708648.
PDB [P14]:  7P38   

201: Profiling cellular diversity in sponges informs animal cell type and nervous system evolution.
Musser JM, Schippers KJ, Nickel M, Mizzon G, Kohn AB, Pape C, Ronchi P, Papadopoulos N, Tarashansky AJ, Hammel JU, Wolf F, Liang C, Hernández-Plaza A, Cantalapiedra CP, Achim K, Schieber NL, Pan L, Ruperti F, Francis WR, Vargas S, Kling S, Renkert M, Polikarpov M, Bourenkov G, Feuda R, Gaspar I, Burkhardt P, Wang B, Bork P, Beck M, Schneider TR, Kreshuk A, Wörheide G, Huerta-Cepas J, Schwab Y, Moroz LL, Arendt D.
Science. 2021 Nov 5;374(6568):717-723.
DOI: 10.1126/science.abj2949.  |   PUBMED: 34735222.  |   IF(2018) = 41.1
PDB [P14]:   

200: Structural basis of cytokine-mediated activation of ALK family receptors.
De Munck S, Provost M, Kurikawa M, Omori I, Mukohyama J, Felix J, Bloch Y, Abdel-Wahab O, Bazan JF, Yoshimi A, Savvides SN.
Nature. (2021 Oct 13). Epub ahead of print
DOI: 10.1038/s41586-021-03959-5  |   PUBMED: 34646012  |   IF(2018) = 43.1
PDB [P13P14]:  7NX4  7NX2  7NX1   

199: Structural and catalytic characterization of Blastochloris viridis and Pseudomonas aeruginosa homospermidine synthases supports the essential role of cation-π interaction.
Helfrich F, Scheidig AJ.
Acta Crystallogr D Struct Biol (2021 Oct)77:1317-1335
DOI: 10.1107/s2059798321008937  |   PUBMED: 34605434
PDB [P13P14]:  6Y87  6SEP  6S6G  4W8G  6S49  6S4D  6S65  6S3X  6S72   

198: The CTPase activity of ParB determines the size and dynamics of prokaryotic DNA partition complexes.
Osorio-Valeriano M, Altegoer F, Das CK, Steinchen W, Panis G, Connolley L, Giacomelli G, Feddersen H, Corrales-Guerrero L, Giammarinaro PI, Hanßmann J, Bramkamp M, Viollier PH, Murray S, Schäfer LV, Bange G, Thanbichler M.
Mol Cell. (2021 Oct)81:3992-4007.e10
DOI: 10.1016/j.molcel.2021.09.004  |   PUBMED: 34562373  |   IF(2018) = 14.5
PDB [P14]:  7BNR   

197: Considerations Regarding Activity Determinants of Fungal Polyphenol Oxidases Based on Mutational and Structural Studies.
Nikolaivits E, Valmas A, Dedes G, Topakas E, Dimarogona M.
Appl Environ Microbiol. (2021 May)87:pp. UNK
DOI: 10.1128/aem.00396-21  |   PUBMED: 33741634
PDB [P14]:  6Z1S   

196: Cesium based phasing of macromolecules: a general easy to use approach for solving the phase problem.
Koelmel W, Kuper J, Kisker C.
Sci Rep. (2021 Aug)11:17038
DOI: 10.1038/s41598-021-95186-1  |   PUBMED: 34426585  |   IF(2018) = 4.1
PDB [P14]:  7BMR  7BMU  7BMO  7BMQ   

195: BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture.
Bandera AM, Bartho J, Lammens K, Drexler DJ, Kleinschwärzer J, Hopfner KP, Witte G.
Nucleic Acids Res. (2021 Sep)49:10166-10177
DOI: 10.1093/nar/gkab736  |   PUBMED: 34432045  |   IF(2018) = 11.1
PDB [P13P14]:  7B5U  7B5T  7B5W   

194: Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli.
Hamborg L, Granata D, Olsen JG, Roche JV, Pedersen LE, Nielsen AT, Lindorff-Larsen K, Teilum K.
Commun Biol. (2021 Aug)4:980
DOI: 10.1038/s42003-021-02490-7  |   PUBMED: 34408246  |   IF(2019) = 12.1
PDB [P13P14]:  7A3M  7AON  7AOK   

193: Structure and mechanism of secondary sulfonamide binding to carbonic anhydrases.
Baronas D, Dudutienė V, Paketurytė V, Kairys V, Smirnov A, Juozapaitienė V, Vaškevičius A, Manakova E, Gražulis S, Zubrienė A, Matulis D.
Eur Biophys J. (2021 Jul)UNK:pp. UNK
DOI: 10.1007/s00249-021-01561-1  |   PUBMED: 34328515
PDB [P13P14]:  7AES  7AEQ  7AGN   

192: Conformational changes of loops highlight a potential binding site in Rhodococcus equi VapB.
Geerds C, Haas A, Niemann HH.
Acta Crystallogr F Struct Biol Commun. (2021 Aug)77:246-253
DOI: 10.1107/s2053230x2100738x  |   PUBMED: 34341190  |   IF(2019) = 0.97
PDB [P14]:  7B1Z   

191: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Verstraete K, Verschueren KHG, Dansercoer A, Savvides SN.
Nat Struct Mol Biol. 2021 Aug;28(8):636-638. Epub 2021 Jul 22.
DOI: 10.1038/s41594-021-00624-3  |   PUBMED: 34294920  |   IF(2019) = 11.7
PDB [P14]:  6ZNW   

190: Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography.
Geier B, Oetjen J, Ruthensteiner B, Polikarpov M, Gruber-Vodicka HR, Liebeke M.
Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2023773118.
DOI: 10.1073/pnas.2023773118.  |   PUBMED: 34183413   |   IF(2019) = 9.4
PDB [P14]:   

189: Neutron structures of Leishmania mexicana triosephosphate isomerase in complex with reaction-intermediate mimics shed light on the proton-shuttling steps.
Kelpšas V, Caldararu O, Blakeley MP, Coquelle N, Wierenga RK, Ryde U, von Wachenfeldt C, Oksanen E.
IUCrJ. (2021 Jul)8:633-643
DOI: 10.1107/s2052252521004619  |   PUBMED: 34258011  |   IF(2020) = 4
PDB [P14]:  7AZ9  7AZA   

188: Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners.
Marcelot A, Petitalot A, Ropars V, Le Du MH, Samson C, Dubois S, Hoffmann G, Miron S, Cuniasse P, Marquez JA, Thai R, Theillet FX, Zinn-Justin S.
Nucleic Acids Res. (2021 Apr)49:3841-3855
DOI: 10.1093/nar/gkab184  |   PUBMED: 33744941  |   IF(2018) = 11.1
PDB [P14]:  7ABM   

187: Mutation-induced dimerization of transforming growth factor-β-induced protein may drive protein aggregation in granular corneal dystrophy.
Nielsen NS, Gadeberg TAF, Poulsen ET, Harwood SL, Weberskov CE, Pedersen JS, Andersen GR, Enghild JJ.
J Biol Chem. (2021 Jun)297:100858
DOI: 10.1016/j.jbc.2021.100858  |   PUBMED: 34097874  |   IF(2018) = 4.1
PDB [P13P14]:  7AS7  7ASC  7ASG   

186: Halogen Atoms in the Protein-Ligand System. Structural and Thermodynamic Studies of the Binding of Bromobenzotriazoles by the Catalytic Subunit of Human Protein Kinase CK2.
Czapinska H, Winiewska-Szajewska M, Szymaniec-Rutkowska A, Piasecka A, Bochtler M, Poznański J.
J Phys Chem B. (2021 Mar)125:2491-2503
DOI: 10.1021/acs.jpcb.0c10264  |   PUBMED: 33689348
PDB [P14]:  6TLU  6TLS  6TLV  6TLL  6TLO  6TLR  6TLW   

185: Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin.
Sponga A, Arolas JL, Schwarz TC, Jeffries CM, Rodriguez Chamorro A, Kostan J, Ghisleni A, Drepper F, Polyansky A, De Almeida Ribeiro E, Pedron M, Zawadzka-Kazimierczuk A, Mlynek G, Peterbauer T, Doto P, Schreiner C, Hollerl E, Mateos B, Geist L, Faulkner G, Kozminski W, Svergun DI, Warscheid B, Zagrovic B, Gautel M, Konrat R, Djinović-Carugo K.
Sci Adv. 2021 May 28; 7(22):eabg7653.
DOI: 10.1126/sciadv.abg7653  |   PUBMED: 34049882  |   IF(2018) = 12.5
PDB [P14]:  7A8T   

184: Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.
Sekulovski S, Devant P, Panizza S, Gogakos T, Pitiriciu A, Heitmeier K, Ramsay EP, Barth M, Schmidt C, Tuschl T, Baas F, Weitzer S, Martinez J, Trowitzsch S.
Nat Commun. 2021 Sep 28;12(1):5610.
DOI: 10.1038/s41467-021-25870-3  |   PUBMED: 34584079  |   IF(2022) = 14.9
PDB [P14]:  6Z9U   

183: Low Carbon Footprint Recycling of Post-Consumer PET Plastic with a Metagenomic Polyester Hydrolase.
Sonnendecker C, Oeser J, Richter PK, Hille P, Zhao Z, Fischer C, Lippold H, Blázquez-Sánchez P, Engelberger F, Ramírez-Sarmiento CA, Oeser T, Lihanova Y, Frank R, Jahnke HG, Billig S, Abel B, Sträter N, Matysik J, Zimmermann W.
ChemSusChem. (2021 Jun)UNK:pp. UNK
DOI: 10.1002/cssc.202101062  |   PUBMED: 34129279  |   IF(2019) = 7.692
PDB [P14]:  7NEI   

182: Targeting a Cryptic Pocket in a Protein-Protein Contact by Disulfide-Induced Rupture of a Homodimeric Interface.
Nguyen D, Xie X, Jakobi S, Terwesten F, Metz A, Nguyen TXP, Palchykov VA, Heine A, Reuter K, Klebe G.
ACS Chem Biol. (2021 Jun)16:1090-1098
DOI: 10.1021/acschembio.1c00296  |   PUBMED: 34081441  |   IF(2019) = 4.43
PDB [P13P14]:  7A4X  7ADN   

181: A simple vapor-diffusion method enables protein crystallization inside the HARE serial crystallography chip.
Norton-Baker B, Mehrabi P, Boger J, Schönherr R, von Stetten D, Schikora H, Kwok AO, Martin RW, Miller RJD, Redecke L, Schulz EC.
Acta Crystallogr D Struct Biol. (2021 Jun)77:820-834
DOI: 10.1107/s2059798321003855  |   PUBMED: 34076595  |   IF(2018) = 3.2
PDB [P14]:  7NJH  7NJG  7NJJ  7NJI  7NJE  7NKF  7NJF   

180: Single tryptophan Y160W mutant of homooligomeric E. coli purine nucleoside phosphorylase implies that dimers forming the hexamer are functionally not equivalent.
Narczyk M, Mioduszewski Ł, Oksiejuk A, Winiewska-Szajewska M, Wielgus-Kutrowska B, Gojdź A, Cieśla J, Bzowska A.
Sci Rep. (2021 May)11:11144
DOI: 10.1038/s41598-021-90472-4  |   PUBMED: 34045551  |   IF(2018) = 4.1
PDB [P14]:  6XZ2   

179: Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding.
Yperman K, Papageorgiou AC, Merceron R, De Munck S, Bloch Y, Eeckhout D, Jiang Q, Tack P, Grigoryan R, Evangelidis T, Van Leene J, Vincze L, Vandenabeele P, Vanhaecke F, Potocký M, De Jaeger G, Savvides SN, Tripsianes K, Pleskot R, Van Damme D.
Nat Commun. (2021 May)12:3050
DOI: 10.1038/s41467-021-23314-6  |   PUBMED: 34031427  |   IF(2022) = 14.9
PDB [P14]:  6YIG   

178: A lysine-cysteine redox switch with an NOS bridge regulates enzyme function.
Wensien M, von Pappenheim FR, Funk LM, Kloskowski P, Curth U, Diederichsen U, Uranga J, Ye J, Fang P, Pan KT, Urlaub H, Mata RA, Sautner V, Tittmann K.
Nature. 2021 May;593(7859):460-464. Epub 2021 May 5.
DOI: 10.1038/s41586-021-03513-3  |   PUBMED: 33953398  |   IF(2018) = 43.1
PDB [P14]:  6ZWJ  7BBW  7BBX  6ZWF  6ZX4  6ZWH   

177: The structure of POMGNT2 provides new insights into the mechanism to determine the functional O-mannosylation site on α-dystroglycan.
Imae R, Kuwabara N, Manya H, Tanaka T, Tsuyuguchi M, Mizuno M, Endo T, Kato R.
Genes Cells. (2021 Apr)UNK:pp. UNK
DOI: 10.1111/gtc.12853  |   PUBMED: 33893702  |   IF(2019) = 1.65
PDB [P14]:  7E9K   

176: X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.
Günther S, Reinke PYA, Fernández-García Y, Lieske J, Lane TJ, Ginn HM, Koua FHM, Ehrt C, Ewert W, Oberthuer D, Yefanov O, Meier S, Lorenzen K, Krichel B, Kopicki JD, Gelisio L, Brehm W, Dunkel I, Seychell B, Gieseler H, Norton-Baker B, Escudero-Pérez B, Domaracky M, Saouane S, Tolstikova A, White TA, Hänle A, Groessler M, Fleckenstein H, Trost F, Galchenkova M, Gevorkov Y, Li C, Awel S, Peck A, Barthelmess M, Schluenzen F, Lourdu Xavier P, Werner N, Andaleeb H, Ullah N, Falke S, Srinivasan V, França BA, Schwinzer M, Brognaro H, Rogers C, Melo D, Zaitseva-Doyle JJ, Knoska J, Peña-Murillo GE, Mashhour AR, Hennicke V, Fischer P, Hakanpää J, Meyer J, Gribbon P, Ellinger B, Kuzikov M, Wolf M, Beccari AR, Bourenkov G, von Stetten D, Pompidor G, Bento I, Panneerselvam S, Karpics I, Schneider TR, Garcia-Alai MM, Niebling S, Günther C, Schmidt C, Schubert R, Han H, Boger J, Monteiro DCF, Zhang L, Sun X, Pletzer-Zelgert J, Wollenhaupt J, Feiler CG, Weiss MS, Schulz EC, Mehrabi P, Karničar K, Usenik A, Loboda J, Tidow H, Chari A, Hilgenfeld R, Uetrecht C, Cox R, Zaliani A, Beck T, Rarey M, Günther S, Turk D, Hinrichs W, Chapman HN, Pearson AR, Betzel C, Meents A.
Science. (2021 May 7) 372(6542):642-646
DOI: 10.1126/science.abf7945  |   PUBMED: 33811162  |   IF(2018) = 41.1
PDB [P14]:  7AXO   

175: The molecular basis of spectral tuning in blue- and red-shifted flavin-binding fluorescent proteins.
Röllen K, Granzin J, Remeeva A, Davari MD, Gensch T, Nazarenko VV, Kovalev K, Bogorodskiy A, Borshchevskiy V, Hemmer S, Schwaneberg U, Gordeliy V, Jaeger KE, Batra-Safferling R, Gushchin I, Krauss U.
J Biol Chem. (2021 Apr)UNK:100662
DOI: 10.1016/j.jbc.2021.100662  |   PUBMED: 33862085  |   IF(2018) = 4.1
PDB [P13P14]:  7AB7   

174: Serial femtosecond and serial synchrotron crystallography can yield data of equivalent quality: A systematic comparison.
Mehrabi P, Bücker R, Bourenkov G, Ginn HM, von Stetten D, Müller-Werkmeister HM, Kuo A, Morizumi T, Eger BT, Ou WL, Oghbaey S, Sarracini A, Besaw JE, Pare-Labrosse O, Meier S, Schikora H, Tellkamp F, Marx A, Sherrell DA, Axford D, Owen RL, Ernst OP, Pai EF, Schulz EC, Miller RJD.
Sci Adv. (2021 Mar 17) 7(12):eabf1380
DOI: 10.1126/sciadv.abf1380  |   PUBMED: 33731353  |   IF(2018) = 12.5
PDB [P14]:  7A42  7A44   

173: Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
Pallesen JS, Narayanan D, Tran KT, Solbak SMØ, Marseglia G, Sørensen LME, Høj LJ, Munafò F, Carmona RMC, Garcia AD, Desu HL, Brambilla R, Johansen TN, Popowicz GM, Sattler M, Gajhede M, Bach A.
J Med Chem. (2021 Apr)64:4623-4661
DOI: 10.1021/acs.jmedchem.0c02094  |   PUBMED: 33818106  |   IF(2018) = 6.1
PDB [P13P14]:  6ZF4  6ZF5  6ZF7  6ZF0  6ZF1  6ZF2  6ZF3  6ZF6   

172: Characterization of porphobilinogen deaminase mutants reveals that arginine-173 is crucial for polypyrrole elongation mechanism.
Bustad HJ, Kallio JP, Laitaoja M, Toska K, Kursula I, Martinez A, Jänis J.
iScience. (2021 Mar)24:102152
DOI: 10.1016/j.isci.2021.102152  |   PUBMED: 33665570  |   IF(2020) = 4
PDB [P13P14]:  7AAJ  7AAK   

171: Cell-penetrating Alphabody protein scaffolds for intracellular drug targeting.
Pannecoucke E, Van Trimpont M, Desmet J, Pieters T, Reunes L, Demoen L, Vuylsteke M, Loverix S, Vandenbroucke K, Alard P, Henderikx P, Deroo S, Baatz F, Lorent E, Thiolloy S, Somers K, McGrath Y, Van Vlierberghe P, Lasters I, Savvides SN.
Sci Adv. (2021 Mar)7:pp. UNK
DOI: 10.1126/sciadv.abe1682  |   PUBMED: 33771865  |   IF(2018) = 12.5
PDB [P14]:  6ZL1   

170: Structural insights into the inhibition of glycine reuptake.
Shahsavar A, Stohler P, Bourenkov G, Zimmermann I, Siegrist M, Guba W, Pinard E, Sinning S, Seeger MA, Schneider TR, Dawson RJP, Nissen P.
Nature (2021 Mar)591:677-681
DOI: 10.1038/s41586-021-03274-z  |   PUBMED: 33658720  |   IF(2018) = 43.1
PDB [P14]:  6ZPL  6ZBV   

169: The structure of Prp2 bound to RNA and ADP-BeF3- reveals structural features important for RNA unwinding by DEAH-box ATPases.
Hamann F, Zimmerningkat LC, Becker RA, Garbers TB, Neumann P, Hub JS, Ficner R.
Acta Crystallogr D Struct Biol. (2021 Apr)77:496-509
DOI: 10.1107/s2059798321001194  |   PUBMED: 33825710  |   IF(2018) = 3.2
PDB [P14]:  6ZM2   

168: Structural basis of Naa20 activity towards a canonical NatB substrate.
Layer D, Kopp J, Fontanillo M, Köhn M, Lapouge K, Sinning I.
Commun Biol. 2021 Jan 4;4(1):2.
DOI: 10.1038/s42003-020-01546-4.  |   PUBMED: 33398031  |   IF(2019) = 12.1
PDB [P14]:  6ZMP   

167: Structural properties and peptide ligand binding of the capsid homology domains of human Arc.
Hallin EI, Bramham CR, Kursula P.
Biochem Biophys Rep. (2021 Jul)26:100975
DOI: 10.1016/j.bbrep.2021.100975  |   PUBMED: 33732907
PDB [P13P14]:  6TQ0  6TNO  6TN7  6TNQ   

166: The amphibian antimicrobial peptide uperin 3.5 is a cross-α/cross-β chameleon functional amyloid
Salinas N, Tayeb-Fligelman E, Sammito MD, Bloch D, Jelinek R, Noy D, Usón I, Landau M
Proc Natl Acad Sci U S A. 118(3):e2014442118.
DOI: 10.1073/pnas.2014442118  |   PUBMED: 33431675  |   IF(2019) = 9.4
PDB [P14]:   

Number of publications for 2021: 43


165: The copper(II)-binding tripeptide GHK, a valuable crystallization and phasing tag for macromolecular crystallography.
Mehr A, Henneberg F, Chari A, Görlich D, Huyton T.
Acta Crystallogr D Struct Biol. 2020 Dec 1;76(Pt 12):1222-1232.
DOI: 10.1107/S2059798320013741.  |   PUBMED: 33263328  |   IF(2018) = 3.2
PDB [P14]:   

164: RIM-binding protein couples synaptic vesicle recruitment to release sites.
Petzoldt AG, Götz TWB, Driller JH, Lützkendorf J, Reddy-Alla S, Matkovic-Rachid T, Liu S, Knoche E, Mertel S, Ugorets V, Lehmann M, Ramesh N, Beuschel CB, Kuropka B, Freund C, Stelzl U, Loll B, Liu F, Wahl MC, Sigrist SJ.
J Cell Biol. 2020 Jul 6;219(7):e201902059.
DOI: 10.1083/jcb.201902059.  |   PUBMED: 32369542  |   IF(2018) = 8.8
PDB [P14]:   

163: Serial synchrotron crystallography for time-resolved structural biology.
Pearson AR, Mehrabi P.
Curr Opin Struct Biol. 2020 Dec;65:168-174.
DOI: 10.1016/  |   PUBMED: 32846363.
PDB [P14]:   

162: The HARE chip for efficient time-resolved serial synchrotron crystallography.
Mehrabi P, Müller-Werkmeister HM, Leimkohl JP, Schikora H, Ninkovic J, Krivokuca S, Andriček L, Epp SW, Sherrell D, Owen RL, Pearson AR, Tellkamp F, Schulz EC, Miller RJD.
J Synchrotron Radiat. 2020 Mar 1;27(Pt 2):360-370.
DOI: 10.1107/S1600577520000685.  |   PUBMED: 32153274
PDB [P14]:   

161: Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7.
Hanke S, Tindall CA, Pippel J, Ulbricht D, Pirotte B, Reboud-Ravaux M, Heiker JT, Sträter N.
J Med Chem. 2020 Jun 11;63(11):5723-5733.
DOI: 10.1021/acs.jmedchem.9b01806  |   PUBMED: 32374603  |   IF(2018) = 6.1
PDB [P14]:   

160: High-resolution structural insights into the heliorhodopsin family.
Kovalev K, Volkov D, Astashkin R, Alekseev A, Gushchin I, Haro-Moreno JM, Chizhov I, Siletsky S, Mamedov M, Rogachev A, Balandin T, Borshchevskiy V, Popov A, Bourenkov G, Bamberg E, Rodriguez-Valera F, Büldt G, Gordeliy V.
Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4131-4141.
DOI: 10.1073/pnas.1915888117  |   PUBMED: 32034096  |   IF(2019) = 9.4
PDB [P14]:   

159: Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake.
Jakobi AJ, Huber ST, Mortensen SA, Schultz SW, Palara A, Kuhm T, Shrestha BK, Lamark T, Hagen WJH, Wilmanns M, Johansen T, Brech A, Sachse C.
Nat Commun. 2020 Jan 23;11(1):440.
DOI: 10.1038/s41467-020-14343-8  |   PUBMED: 31974402  |   IF(2022) = 14.9
PDB [P14]:   

158: The extracellular juncture domains in the intimin passenger adopt a constitutively extended conformation inducing restraints to its sphere of action.
Weikum J, Kulakova A, Tesei G, Yoshimoto S, Jægerum LV, Schütz M, Hori K, Skepö M, Harris P, Leo Morth JP
Sci Rep. 2020 Dec 4;10(1):21249.
DOI: 10.1038/s41598-020-77706-7  |   PUBMED: 33277518  |   IF(2018) = 4.1
PDB [P14]:  6TQD  6TPL   

157: Diamond refractive micro-lenses for full-field X-ray imaging and microscopy produced with ion beam lithography.
Medvedskaya, P., Lyatun, I., Shevyrtalov, S., Polikarpov, M., Snigireva, I., Yunkin, V., & Snigirev, A.
Optics express. 28(4), 4773-S785.
DOI: 10.1364/OE.384647  |   PUBMED: 32121709  |   IF(2019) = 3.67
PDB [P14]:   

156: Crystal structures of a novel family IV esterase in free and substrate-bound form.
Höppner A, Bollinger A, Kobus S, Thies S, Coscolín C, Ferrer M, Jaeger KE, Smits SHJ.
FEBS J. (2020 Dec) UNK:pp. UNK
DOI: 10.1111/febs.15680  |   PUBMED: 33342083  |   IF(2018) = 4.7
PDB [P14]:  6Z68   

155: Phi class glutathione transferases as molecular targets towards multiple-herbicide resistance: Inhibition analysis and pharmacophore design.
Georgakis N, Poudel N, Vlachakis D, Papageorgiou AC, Labrou NE.
Plant Physiol Biochem. (2020 Nov)UNK:pp. UNK
DOI: 10.1016/j.plaphy.2020.11.018  |   PUBMED: 33257232  |   IF(2019) = 3.72
PDB [P14]:  6ZB6   

154: Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection.
Anjanappa R, Garcia-Alai M, Kopicki JD, Lockhauserbäumer J, Aboelmagd M, Hinrichs J, Nemtanu IM, Uetrecht C, Zacharias M, Springer S, Meijers R.
Nat Commun. (2020 Mar)11:1314
DOI: 10.1038/s41467-020-14862-4  |   PUBMED: 32161266  |   IF(2022) = 14.9
PDB [P14]:  6TDP  6TDO  6TDQ  6TDS  6TDR   

153: Exposing the distinctive modular behavior of β-strands and α-helices in folded proteins.
Wang H, Logan DT, Danielsson J, Oliveberg M.
Proc Natl Acad Sci U S A. (2020 Nov) 117:28775-28783
DOI: 10.1073/pnas.1920455117  |   PUBMED: 33148805  |   IF(2019) = 9.4
PDB [P14]:  6I6E  6I69  6I6I  6I6O   

152: Nocardamine-Dependent Iron Uptake in Pseudomonas aeruginosa: Exclusive Involvement of the FoxA Outer Membrane Transporter.
Normant V, Josts I, Kuhn L, Perraud Q, Fritsch S, Hammann P, Mislin GLA, Tidow H, Schalk IJ.
ACS Chem Biol. (2020 Oct)15:2741-2751
DOI: 10.1021/acschembio.0c00535  |   PUBMED: 32902248  |   IF(2019) = 4.43
PDB [P14]:  6Z8A   

151: Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38.
Kirsch K, Zeke A, Tőke O, Sok P, Sethi A, Sebő A, Kumar GS, Egri P, Póti ÁL, Gooley P, Peti W, Bento I, Alexa A, Reményi A.
Nat Commun. (2020 Nov)11:5769
DOI: 10.1038/s41467-020-19582-3  |   PUBMED: 33188182  |   IF(2022) = 14.9
PDB [P14]:  6ZQS  6ZR5   

150: A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
Stefano JE, Lord DM, Zhou Y, Jaworski J, Hopke J, Travaline T, Zhang N, Wong K, Lennon A, He T, Bric-Furlong E, Cherrie C, Magnay T, Remy E, Brondyk W, Qiu H, Radošević K.
J Biol Chem. (2020 Oct)UNK:pp. UNK
DOI: 10.1074/jbc.ra120.012395  |   PUBMED: 33122192  |   IF(2018) = 4.1
PDB [P14]:  6VC9   

149: Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein.
Manav MC, Van LB, Lin J, Fuglsang A, Peng X, Brodersen DE.
Nat Commun. (2020 Nov)11:5993
DOI: 10.1038/s41467-020-19847-x  |   PUBMED: 33239638  |   IF(2022) = 14.9
PDB [P14]:  6THH   

148: Isoform-Selective Enzyme Inhibitors by Exploring Pocket Size According to the Lock-and-Key Principle.
Dudutiene V, Zubriene A, Kairys V, Smirnov A, Smirnovien J, Leitans J, Kazaks A, Tars K, Manakova L, Gražulis S, Matulis D.
Biophys J (2020 Sep)UNK:pp. UNK
DOI: 10.1016/j.bpj.2020.08.037  |   PUBMED: 32971003
PDB [P14]:  6T4N  6T4O  6T81  6T5Q  6T5P  6T5C   

147: Multiscale computation delivers organophosphorus reactivity and stereoselectivity to immunoglobulin scavengers.
Mokrushina YA, Golovin AV, Smirnov IV, Chatziefthimiou SD, Stepanova AV, Bobik TV, Zalevsky AO, Zlobin AS, Konovalov KA, Terekhov SS, Stepanov AV, Pipiya SO, Shamborant OG, Round E, Belogurov AA, Bourenkov G, Makarov AA, Wilmanns M, Xie J, Blackburn GM, Gabibov AG, Lerner RA.
Proc Natl Acad Sci U S A. (2020 Aug) UNK:pp. UNK
DOI: 10.1073/pnas.2010317117  |   PUBMED: 32859757  |   IF(2019) = 9.4
PDB [P14]:  6Y49  6Y1M  6Y1K  6Y1L   

146: Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions.
Stalmans G, Lilina AV, Vermeire PJ, Fiala J, Novák P, Strelkov SV.
Cells. (2020 Jul) 9:pp. UNK
DOI: 10.3390/cells9071633  |   PUBMED: 32645958  |   IF(2019) = 4.4
PDB [-P14]:  6YSH   

145: Structural and mechanistic basis of capsule O-acetylation in Neisseria meningitidis serogroup A.
Fiebig T, Cramer JT, Bethe A, Baruch P, Curth U, Führing JI, Buettner FFR, Vogel U, Schubert M, Fedorov R, Mühlenhoff M.
Nat Commun. (2020 Sep)11:4723
DOI: 10.1038/s41467-020-18464-y  |   PUBMED: 32948778  |   IF(2022) = 14.9
PDB [P14]:  6YUS  6YUQ   

144: Structural and biochemical characterization of a family 7 highly thermostable endoglucanase from the fungus Rasamsonia emersonii.
Schiano-di-Cola C, Kołaczkowski B, Sørensen TH, Christensen SJ, Cavaleiro AM, Windahl MS, Borch K, Morth JP, Westh P.
FEBS J. (2020 Jun) 287:2577-2596
DOI: 10.1111/febs.15151  |   PUBMED: 31755197  |   IF(2018) = 4.7
PDB [P14]:  6SU8   

143: The Human LL-37(17-29) antimicrobial peptide reveals a functional supramolecular structure.
Engelberg Y, Landau M
Nat Commun. (2020 Aug 4) 11(1):3894.
DOI: 10.1038/s41467-020-17736-x  |   PUBMED: 32753597  |   IF(2022) = 14.9
PDB [P14]:  6S6M   

142: Molecular mechanism of light-driven sodium pumping.
Kovalev K, Astashkin R, Gushchin I, Orekhov P, Volkov D, Zinovev E, Marin E, Rulev M, Alekseev A, Royant A, Carpentier P, Vaganova S, Zabelskii D, Baeken C, Sergeev I, Balandin T, Bourenkov G, Carpena X, Boer R, Maliar N, Borshchevskiy V, Buldt G, Bamberg E, Gordeliy V
Nat Commun. (2020 May 1) 11(1):2137.
DOI: 10.1038/s41467-020-16032-y  |   PUBMED: 32358514  |   IF(2022) = 14.9
PDB [P14]:  6YC2  6YC3  6YC4   

141: Architecture and functional dynamics of the pentafunctional AROM complex.
Arora Veraszto H, Logotheti M, Albrecht R, Leitner A, Zhu H, Hartmann MD,
Nat Chem Biol. 2020 Jul 6.
DOI: 10.1038/s41589-020-0587-9  |   PUBMED: 32632294  |   IF(2020) = 41.8
PDB [P14]:  6HQV   

140: Crystal structure and interactions of the Tof1-Csm3 (Timeless-Tipin) fork protection complex.
Grabarczyk DB,
Nucleic Acids Res. 2020 Jul 9;48(12):6996-7004.
DOI: 10.1093/nar/gkaa456  |   PUBMED: 32469068  |   IF(2018) = 11.1
PDB [P14]:  6XWX   

139: Structural basis for antibiotic action of the B1 antivitamin 2'-methoxy-thiamine.
Rabe von Pappenheim F, Aldeghi M, Shome B, Begley T, de Groot BL, Tittmann K.
Nat Chem Biol. (2020 Aug) UNK:pp. UNK
DOI: 10.1038/s41589-020-0628-4  |   PUBMED: 32839604  |   IF(2020) = 41.8
PDB [P14]:  6TJ8  6TJ9   

138: Structural signatures in EPR3 define a unique class of plant carbohydrate receptors.
Wong JEMM, Gysel K, Birkefeldt TG, Vinther M, Muszyński A, Azadi P, Laursen NS, Sullivan JT, Ronson CW, Stougaard J, Andersen KR.
Nat Commun. (2020 Jul)11:3797
DOI: 10.1038/s41467-020-17568-9  |   PUBMED: 32732998  |   IF(2022) = 14.9
PDB [P14]:  6QUP   

137: Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System.
Laursen NS, Pedersen DV, Gytz H, Zarantonello A, Bernth Jensen JM, Hansen AG, Thiel S, Andersen GR.
Front Immunol. (2020 )11:1504
DOI: 10.3389/fimmu.2020.01504  |   PUBMED: 32849513  |   IF(2018) = 6.4
PDB [P14]:  6Z6V   

136: Characterization of Inhibition Reveals Distinctive Properties for Human and Saccharomyces cerevisiae CRM1.
Shaikhqasem A, Dickmanns A, Neumann P, Ficner R.
J Med Chem. 2020 Jul 7545-7558
DOI: DOI: 10.1021/acs.jmedchem.0c00143  |   PUBMED: 32585100  |   IF(2018) = 6.1
PDB [P14]:  6TVO   

135: MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases.
Sok P, Gógl G, Kumar GS, Alexa A, Singh N, Kirsch K, Sebő A, Drahos L, Gáspári Z, Peti W, Reményi A.
Structure (2020 Jul) pp. UNK
DOI: DOI: 10.1016/j.str.2020.06.007  |   PUBMED: 32649858  |   IF(2018) = 4.9
PDB [P14]:  6TCA   

134: Crystal and solution structures of fragments of the human leucocyte commonantigen-related protein.
Vilstrup J, Simonsen A, Birkefeldt T, Strandbygard D, Lyngso J, Pedersen JS, Thirup S,
Acta Crystallogr D Struct Biol. 2020 May 1;76(Pt 5):406-417.
DOI: 10.1107/S2059798320003885  |   PUBMED: 32355037  |   IF(2018) = 3.2
PDB [P14]:  6TPV   

133: Molecular basis of MKLP2-dependent Aurora B transport from chromatin to theanaphase central spindle.
Serena M, Bastos RN, Elliott PR, Barr FA,
J Cell Biol. 2020 Jul 6;219(7).
DOI: 10.1083/JCB.201910059  |   PUBMED: 32356865  |   IF(2018) = 8.8
PDB [P14]:  6YIE   

132: Crossing the Border: From Keto- to Imine Reduction in Short-ChainDehydrogenases/Reductases.
Muller M, Roth S, Stockinger P, Steff J, Steimle S, Sautner V, Tittmann K, Pleiss J,
ChemBioChem. 2020 Apr 21.
DOI: 10.1002/CBIC.202000233  |   PUBMED: 32315494  |   IF(2018) = 2.6
PDB [P14]:  6Y4D   

131: Structural and functional characterization of the severe fever withthrombocytopenia syndrome virus L protein.
Vogel D, Thorkelsson SR, Quemin ERJ, Meier K, Kouba T, Gogrefe N, Busch C, Reindl S, Gunther S, Cusack S, Grunewald K, Rosenthal M
Nucleic Acids Res. 2020 Jun 4;48(10):5749-5765.
DOI: 10.1093/nar/gkaa253  |   PUBMED: 32313945  |   IF(2018) = 11.1
PDB [P14]:  6XYA   

130: Discovery of a Regulatory Subunit of the Yeast Fatty Acid Synthase.
Singh K, Graf B, Linden A, Sautner V, Urlaub H, Tittmann K, Stark H, Chari A
Cell. 2020 Mar 19;180(6):1130-1143.e20.
DOI: 10.1016/j.cell.2020.02.034  |   PUBMED: 32160528  |   IF(2018) = 36.2
PDB [P14]:  6QL9  6QL7   

129: Halogenated and di-substituted benzenesulfonamides as selective inhibitors ofcarbonic anhydrase isoforms.
Zaksauskas A, Capkauskaite E, Jezepcikas L, Linkuviene V, Paketuryte V, Smirnov A, Leitans J, Kazaks A, Dvinskis E, Manakova E, Grazulis S, Tars K, Matulis D,
Eur J Med Chem. 2020 Jan 1;185:111825.
DOI: 10.1016/J.EJMECH.2019.111825  |   PUBMED: 31740053  |   IF(2018) = 4.8
PDB [P14]:  6R6Y   

Number of publications for 2020: 37


128: Clustering of atomic displacement parameters in bovine trypsin reveals a distributed lattice of atoms with shared chemical properties.
Gagner VA, Lundholm I, Garcia-Bonete MJ, Rodilla H, Friedman R, Zhaunerchyk V, Bourenkov G, Schneider T, Stake J, Katona G,
Sci Rep. 2019 Dec 17;9(1):19281.
DOI: 10.1038/s41598-019-55777-5  |   PUBMED: 31848402  |   IF(2018) = 4.1
PDB [P14]:  6SW0  6SVG  6SVZ  6SVU  6SVW  6RIV  6SVX  6SVD  6SUX  6SVV  6SV9  6SV8  6SVB  6SV0  6SV6  6SVJ  6SVI  6SVN  6SVR   

127: Identification and characterization of a novel chemotype for human TLR8 inhibitors.
Sribar D, Grabowski M, Murgueitio MS, Bermudez M, Weindl G, Wolber G,
Eur J Med Chem. 2019 Oct 1;179:744-752. Epub2019 Jun 29.
DOI: 10.1016/J.EJMECH.2019.06.084  |   PUBMED: 31284084  |   IF(2018) = 4.8
PDB [P14]:  6R6F   

126: Increased versatility despite reduced molecular complexity: evolution, structure and function of metazoan splicing factor PRPF39.
De Bortoli F, Neumann A, Kotte A, Timmermann B, Schuler T, Wahl MC, Loll B, Heyd F,
Nucleic Acids Res. 2019 Jun 20;47(11):5867-5879.
DOI: 10.1093/nar/gkz243  |   PUBMED: 30949712  |   IF(2018) = 11.1
PDB [P14]:   

125: Structure of GTP cyclohydrolase I from Listeria monocytogenes, a potential anti-infective drug target.
Schussler S, Haase I, Perbandt M, Illarionov B, Siemens A, Richter K, Bacher A, Fischer M, Grawert T,
Acta Crystallogr F Struct Biol Commun. 2019 Sep 1;75(Pt 9):586-592. Epub 2019 Aug 30.
DOI: 10.1107/S2053230X19010902  |   PUBMED: 31475925  |   IF(2019) = 0.97
PDB [P14]:  4UQF   

124: Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
Driller R, Ballaschk M, Schmieder P, Uchanska-Ziegler B, Ziegler A, Loll B,
J Biol Chem. 2019 Sep 6;294(36):13269-13279. Epub 2019 Jul 11.
DOI: 10.1074/jbc.RA119.008937  |   PUBMED: 31296658  |   IF(2018) = 4.1
PDB [P14]:  5IB3   

123: Visualization of protein crystals by high-energy phase-contrast X-ray imaging.
Polikarpov M, Bourenkov G, Snigireva I, Snigirev A, Zimmermann S, Csanko K, Brockhauser S, Schneider TR,
Acta Crystallogr D Struct Biol. 2019 Nov 1;75(Pt 11):947-958. Epub 2019 Oct 31.
DOI: 10.1107/S2059798319011379  |   PUBMED: 31692469  |   IF(2018) = 3.2
PDB [P14]:   

122: Unique structure and function of viral rhodopsins.
Bratanov D, Kovalev K, Machtens JP, Astashkin R, Chizhov I, Soloviov D, Volkov D, Polovinkin V, Zabelskii D, Mager T, Gushchin I, Rokitskaya T, Antonenko Y, Alekseev A, Shevchenko V, Yutin N, Rosselli R, Baeken C, Borshchevskiy V, Bourenkov G, Popov A, Balandin T, Buldt G, Manstein DJ, Rodriguez-Valera F, Fahlke C, Bamberg E, Koonin E, Gordeliy V,
Nat Commun. 2019 Oct 30;10(1):4939.
DOI: 10.1038/S41467-019-12718-0  |   PUBMED: 31666521  |   IF(2022) = 14.9
PDB [P14]:  6SQG  6XYT   

121: Optical performance and radiation stability of polymer X-ray refractive nano-lenses.
Barannikov A, Polikarpov M, Ershov P, Bessonov V, Abrashitova K, Snigireva I, Yunkin V, Bourenkov G, Schneider T, Fedyanin AA, Snigirev A,
J Synchrotron Rad. 2019 May 1;26(Pt 3):714-719. Epub 2019 Apr 1.
DOI: 10.1107/S1600577519001656  |   PUBMED:   |   IF(2018) = 2.5
PDB [P14]:   

120: CRL-based ultra-compact transfocator for X-ray focusing and microscopy.
Narikovich A, Polikarpov M, Barannikov A, Klimova N, Lushnikov A, Lyatun I, Bourenkov G, Zverev D, Panormov I, Sinitsyn A, Snigireva I, Snigirev A,
J Synchrotron Rad. 2019 Jul 1;26(Pt 4):1208-1212. Epub 2019 Jun 18.
DOI: 10.1107/S1600577519005708  |   PUBMED:   |   IF(2018) = 2.5
PDB [P14]:   

119: Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping.
Slyvka A, Zagorskaite E, Czapinska H, Sasnauskas G, Bochtler M,
Nucleic Acids Res. 2019 Nov 14.
DOI: 10.1093/nar/gkz1017  |   PUBMED: 31724709   |   IF(2018) = 11.1
PDB [P14]:  6T22  6T21   

118: Liquid application method for time-resolved analyses by serial synchrotron crystallography.
Mehrabi P, Schulz EC, Agthe M, Horrell S, Bourenkov G, von Stetten D, Leimkohl JP, Schikora H, Schneider TR, Pearson AR, Tellkamp F, Miller RJD
Nat Methods. 2019 Oct;16(10):979-982. Epub 2019Sep 16.
DOI: 10.1038/S41592-019-0553-1  |   PUBMED: 31527838  |   IF(2018) = 28.5
PDB [P14]:  6RNC  6RNB  6RND  6RNF  6QNJ  6QNH  6QNI  6QND  6QNB  6QNC   

117: Low-barrier hydrogen bonds in enzyme cooperativity.
Dai S, Funk LM, von Pappenheim FR, Sautner V, Paulikat M, Schroder B, Uranga J, Mata RA, Tittmann K,
Nature. 2019 Sep 18.
DOI: 10.1038/s41586-019-1581-9  |   PUBMED: 31534226  |   IF(2018) = 43.1
PDB [P13P14]:  6HAD  6HA3  6RJB  6RJC  6HAF   

116: Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.
Pedersen DV, Gadeberg TAF, Thomas C, Wang Y, Joram N, Jensen RK, Mazarakis SMM, Revel M, El Sissy C, Petersen SV, Lindorff-Larsen K, Thiel S, Laursen NS, Fremeaux-Bacchi V, Andersen GR,
Front Immunol. 2019 Aug 22;10:2007. eCollection2019.
DOI: 10.3389/fimmu.2019.02007  |   PUBMED: 31507604  |   IF(2018) = 6.4
PDB [P13P14]:  6SEJ  6RV6  6RUV  6RUR  6RU5  6RU3   

115: Time-resolved crystallography reveals allosteric communication aligned withmolecular breathing.
Mehrabi P, Schulz EC, Dsouza R, Muller-Werkmeister HM, Tellkamp F, Miller RJD, Pai EF,
Science. 2019 Sep 13;365(6458):1167-1170.
DOI: 10.1126/SCIENCE.AAW9904  |   PUBMED: 31515393  |   IF(2018) = 41.1
PDB [P14]:  6QI1  6QHY  6QHX   

114: The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNABinding Domain.
Manav MC, Turnbull KJ, Jurenas D, Garcia-Pino A, Gerdes K, Brodersen DE,
Structure. 2019 Sep 4.
DOI: 10.1016/J.STR.2019.08.008  |   PUBMED: 31495532  |   IF(2018) = 4.9
PDB [P13P14]:  6HPB  6HPC   

113: Engineered Carbonic Anhydrase VI-Mimic Enzyme Switched the Structure andAffinities of Inhibitors.
Kazokaite J, Kairys V, Smirnoviene J, Smirnov A, Manakova E, Tolvanen M, Parkkila S, Matulis D,
Sci Rep. 2019 Sep 3;9(1):12710.
DOI: 10.1038/S41598-019-49094-0  |   PUBMED: 31481705  |   IF(2018) = 4.1
PDB [P14]:  6QL3  6QL2  6QL1   

112: Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S byAutoubiquitination.
Liess AKL, Kucerova A, Schweimer K, Yu L, Roumeliotis TI, Diebold M, Dybkov O, Sotriffer C, Urlaub H, Choudhary JS, Mansfeld J, Lorenz S
Structure. 2019 Jun 4.
DOI: 10.1016/J.STR.2019.05.008  |   PUBMED: 31230944  |   IF(2018) = 4.9
PDB [P14]:  6QH3   

111: Class Id ribonucleotide reductase utilizes a Mn2(IV,III) cofactor and undergoes large conformational changes on metal loading.
Rozman Grinberg I, Berglund S, Hasan M, Lundin D, Ho FM, Magnuson A, Logan DT, Sjoberg BM, Berggren G
J Biol Inorg Chem. 2019 Aug 14.
DOI: 10.1007/S00775-019-01697-8  |   PUBMED: 31414238  |   IF(2018) = 3.6
PDB [P13P14]:  6SF5  6SF4   

110: Structural Insights into Curli CsgA Cross-beta Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents.
Perov S, Lidor O, Salinas N, Golan N, Tayeb-Fligelman E, Deshmukh M, Willbold D, Landau M
PLoS Pathog. 2019 Aug 30;15(8):e1007978. eCollection 2019 Aug.
DOI: 10.1371/journal.ppat.1007978  |   PUBMED: 31469892  |   IF(2018) = 6.1
PDB [P14]:  6G8C  6G8D  6G9G   

109: Crystal structures of the c-di-AMP synthesizing enzyme CdaA.
Heidemann JL, Neumann P, Dickmanns A, Ficner R,
J Biol Chem. 2019 May 22.
DOI: 10.1074/JBC.RA119.009246  |   PUBMED: 31118276  |   IF(2018) = 4.1
PDB [P13P14]:  6HVM  6HVN  6HVL   

108: Protein crystallization promotes type 2 immunity and is reversible by antibodytreatment.
Persson EK, Verstraete K, Heyndrickx I, Gevaert E, Aegerter H, Percier JM, Deswarte K, Verschueren KHG, Dansercoer A, Gras D, Chanez P, Bachert C, Goncalves A, Van Gorp H, De Haard H, Blanchetot C, Saunders M, Hammad H, Savvides SN, Lambrecht BN,
Science. 2019 May 24;364(6442).
DOI: 10.1126/SCIENCE.AAW4295  |   PUBMED: 31123109  |   IF(2018) = 41.1
PDB [P14]:  6QRN  6GKS  6GKQ   

107: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebscycle.
Verschueren KHG, Blanchet C, Felix J, Dansercoer A, De Vos D, Bloch Y, Van Beeumen J, Svergun D, Gutsche I, Savvides SN, Verstraete K,
Nature. 2019 Apr 3.
DOI: 10.1038/S41586-019-1095-5  |   PUBMED: 30944476  |   IF(2018) = 43.1
PDB [P13P14]:  6HXK  6QCL  6QFB   

106: Structural Comparison of Enterococcus faecalis and Human Thymidylate SynthaseComplexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints aboutEnzyme Conformational Variabilities.
Pozzi C, Ferrari S, Luciani R, Tassone G, Costi MP, Mangani S,
Molecules. 2019 Mar 31;24(7).
DOI: 10.3390/MOLECULES24071257  |   PUBMED: 30935102  |   IF(2020) = 3.3
PDB [P14]:  6QXH   

105: Structure-based development of new RAS-effector inhibitors from a combination of active and inactive RAS-binding compounds.
Cruz-Migoni A, Canning P, Quevedo CE, Bataille CJR, Bery N, Miller A, Russell AJ, Phillips SEV, Carr SB, Rabbitts TH,
Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2545-2550. Epub 2019 Jan 25.
DOI: 10.1073/PNAS.1811360116  |   PUBMED: 30683716  |   IF(2019) = 9.4
PDB [P14]:  6GQW  6GQY  6GQX   

104: Enzyme activity and structural features of three single-domain phloemcyclophilins from Brassica napus.
Hanhart P, Falke S, Garbe M, Rose V, Thiess M, Betzel C, Kehr J,
Sci Rep. 2019 Jun 27;9(1):9368.
DOI: 10.1038/s41598-019-45856-y  |   PUBMED: 31249367  |   IF(2018) = 4.1
PDB [P14]:  6HMZ   

Number of publications for 2019: 25


103: Design of two-tail compounds with rotationally fixed benzenesulfonamide ring asinhibitors of carbonic anhydrases.
Zaksauskas A, Capkauskaite E, Jezepcikas L, Linkuviene V, Kisonaite M, Smirnov A, Manakova E, Grazulis S, Matulis D,
Eur J Med Chem. 2018 Aug 5;156:61-78. Epub2018 Jun 27.
DOI: 10.1016/J.EJMECH.2018.06.059  |   PUBMED: 30006175  |   IF(2018) = 4.8
PDB [P14]:  6G6T  6G7A  6G5L   

102: Extreme amyloid polymorphism in Staphylococcus aureus virulent PSMalpha peptides.
Salinas N, Colletier JP, Moshe A, Landau M
Nat Commun. 2018 Aug 29;9(1):3512.
DOI: 10.1038/s41467-018-05490-0  |   PUBMED: 30158633  |   IF(2022) = 14.9
PDB [P14]:  6FHD   

101: The cost of long catalytic loops in folding and stability of the ALS-associatedprotein SOD1.
Yang F, Wang H, Logan DT, Mu X, Danielsson J, Oliveberg M,
J Am Chem Soc. 2018 Oct 25.
DOI: 10.1021/JACS.8B08141  |   PUBMED: 30359015  |   IF(2018) = 14.7
PDB [P14]:  6FLH   

100: The hit-and-return system enables efficient time-resolved serial synchrotron crystallography.
Schulz EC, Mehrabi P, Muller-Werkmeister HM, Tellkamp F, Jha A, Stuart W, Persch E, De Gasparo R, Diederich F, Pai EF, Miller RJD,
Nat Methods. 2018 Nov;15(11):901-904. Epub 2018Oct 30.
DOI: 10.1038/S41592-018-0180-2  |   PUBMED: 30377366  |   IF(2018) = 28.5
PDB [P14]:  6FSX  6GXH  6GXT   

99: Crystal structure of human mARC1 reveals its exceptional position amongeukaryotic molybdenum enzymes.
Kubitza C, Bittner F, Ginsel C, Havemeyer A, Clement B, Scheidig AJ, ORCID: 0000-0002-2382-8818,
Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):11958-11963. Epub 2018 Nov 5.
DOI: 10.1073/pnas.1808576115  |   PUBMED: 30397129  |   IF(2019) = 9.4
PDB [P14]:  6FW2   

98: Towards a comprehensive understanding of the structural dynamics of a bacterialditerpene synthase during catalysis.
Driller R, Janke S, Fuchs M, Warner E, Mhashal AR, Major DT, Christmann M, Bruck T, Loll B
Nat Commun. 2018 Sep 28;9(1):3971.
DOI: 10.1038/S41467-018-06325-8  |   PUBMED: 30266969  |   IF(2022) = 14.9
PDB [P14]:  6GGL   

97: DNA recognition by Arabidopsis transcription factors ABI3 and NGA1
Sasnauskas G, Manakova E, Lapenas K, Kauneckaite K, Siksnys V
FEBS J. 2018 Nov;285(21):4041-4059.
DOI: 10.1111/febs.14649. Epub 2018 Sep 21.  |   PUBMED: 30183137.  |   IF(2018) = 4.7
PDB [P14]:  5OS9   

96: Tripeptide binding in a proton-dependent oligopeptide transporter.
Martinez Molledo M, Quistgaard EM, Low C,
FEBS Lett. 2018 Sep 8.
DOI: 10.1002/1873-3468.13246  |   PUBMED: 30194725  |   IF(2018) = 2.7
PDB [P14]:  6GHJ   

95: Crystal Structure of the Escherichia coli DExH-Box NTPase HrpB.
Pietrzyk-Brzezinska AJ, Absmeier E, Klauck E, Wen Y, Antelmann H, Wahl MC,
Structure. 2018 Aug 13.
DOI: 10.1016/J.STR.2018.07.013  |   PUBMED: 30174149  |   IF(2018) = 4.9
PDB [P14]:  6EUD   

94: Intriguing role of water in protein-ligand binding studied by neutroncrystallography on trypsin complexes.
Schiebel J, Gaspari R, Wulsdorf T, Ngo K, Sohn C, Schrader TE, Cavalli A, Ostermann A, Heine A, Klebe G
Nat Commun. 2018 Sep 3;9(1):3559.
DOI: 10.1038/s41467-018-05769-2  |   PUBMED: 30177695  |   IF(2022) = 14.9
PDB [P14]:  5MNE  5MNN  5MNG  5MNQ  5MNF  5MNH  5MOP  5MOQ  5MOS   

93: Crystal Structure of the Human tRNA Guanine Transglycosylase Catalytic SubunitQTRT1.
Johannsson S, Neumann P, Ficner R,
Biomolecules. 2018 Aug 24;8(3).
DOI: 10.3390/BIOM8030081  |   PUBMED: 30149595  |   IF(2019) = 4.7
PDB [P14]:  6H45  6H42   

92: Structural and Functional Characterization of the BcsG Subunit of the CelluloseSynthase in Salmonella typhimurium.
Sun L, Vella P, Schnell R, Polyakova A, Bourenkov G, Li F, Cimdins A, Schneider TR, Lindqvist Y, Galperin MY, Schneider G, Romling U,
J Mol Biol. 2018 Jul 12.
DOI: 10.1016/j.jmb.2018.07.008  |   PUBMED: 30017920  |   IF(2018) = 5.1
PDB [P14]:  5OLT   

91: Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor.
Sokolov AV, Dadinova LA, Petoukhov MV, Bourenkov G, Dubova KM, Amarantov SV, Volkov VV, Kostevich VA, Gorbunov NP, Grudinina NA, Vasilyev VB, Samygina VR,
Biochemistry (Mosc). 2018 Jun;83(6):701-707.
DOI: 10.1134/S000629791806007X  |   PUBMED: 30195326  |   IF(2018) = 3.0
PDB [P14]:  6FVE   

90: Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein.
Schmidt K, Gardill BR, Kern A, Kirchweger P, Borsch M, Muller YA,
Proc Natl Acad Sci U S A. 2018 May 14.
DOI: 10.1073/PNAS.1716666115  |   PUBMED: 29760101  |   IF(2019) = 9.4
PDB [P14]:  5OM3  5OM5   

89: Crystal structure of pyrrolizidine alkaloid N-oxygenase from the grasshopper Zonocerus variegatus.
Kubitza C, Faust A, Gutt M, ORCID: 0000-0001-5629-7665, Gath L, Ober D, Scheidig AJ,
Acta Crystallogr D Struct Biol. 2018 May 1;74(Pt 5):422-432. Epub 2018 Apr 24.
DOI: 10.1107/S2059798318003510.  |   PUBMED: 29717713  |   IF(2018) = 3.2
PDB [P14]:  5NMX  5NMW   

88: A potent complement factor C3-specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement.
Jensen RK, Pihl R, Gadeberg TAF, Jensen JK, Andersen KR, Thiel S, Laursen NS, Andersen GR,
J Biol Chem. 2018 Apr 27;293(17):6269-6281. Epub2018 Mar 1.
DOI: 10.1107/S1600576717014479  |   PUBMED: 29497000  |   IF(2018) = 4.1
PDB [P14]:  6EHG   

87: Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.
Pernigo S, Chegkazi MS, Yip YY, Treacy C, Glorani G, Hansen K, Politis A, Bui S, Dodding MP, Steiner RA
Elife. 2018 Oct 15;7.
DOI: 10.7554/eLife.38362  |   PUBMED: 30320553  |   IF(2018) = 7.6
PDB [P14]:  6FUZ   

86: p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage.
Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA, Beli P
Nat Commun. 2018 Mar 9;9(1):1017.
DOI: 10.1107/S1600576717014479  |   PUBMED: 29523821  |   IF(2022) = 14.9
PDB [P14]:  6EIH   

85: The Antiviral Activity of the Cellular Glycoprotein LGALS3BP/90K is Species-Specific.
Lodermeyer V, Ssebyatika G, Passos V, Ponnurangam A, Malassa A, Ewald E, Sturzel CM, Kirchhoff F, Rotger M, Falk CS, Telenti A, Krey T, Goffinet C,
J Virol. 2018 May 9.
DOI: 10.1128/JVI.00226-18.  |   PUBMED: 29743357  |   IF(2018) = 4.3
PDB [P14]:  6GFC   

84: Multispecific Substrate Recognition in a Proton-Dependent OligopeptideTransporter.
Martinez Molledo M, Quistgaard EM, Flayhan A, Pieprzyk J, Low C,
Structure. 2018 Mar 6;26(3):467-476.e4. Epub 2018Feb 8.
DOI: 10.1016/j.str.2018.01.005  |   PUBMED: 29429879  |   IF(2018) = 4.9
PDB [P14]:  5OXK  5OXP  5OXO  5OXN  6EIA  5OXQ   

83: Structural basis of DNA target recognition by the B3 domain of Arabidopsisepigenome reader VAL1.
Sasnauskas G, Kauneckaite K, Siksnys V
Nucleic Acids Res. 2018 Apr 6.
DOI: 10.1093/NAR/GKY256  |   PUBMED: 29660015  |   IF(2018) = 11.1
PDB [P14]:  6FAS   

82: The H-subunit of the restriction endonuclease CglI contains a prototype DEAD-Z1helicase-like motor.
Toliusis P, Tamulaitiene G, Grigaitis R, Tuminauskaite D, Silanskas A, Manakova E, Venclovas C, Szczelkun MD, Siksnys V, Zaremba M,
Nucleic Acids Res. 2018 Mar 16;46(5):2560-2572.
DOI: 10.1093/NAR/GKY107  |   PUBMED: 29471489  |   IF(2018) = 11.1
PDB [P14]:  6F1S   

81: Structure Guided Lead Generation toward Nonchiral M. tuberculosis ThymidylateKinase Inhibitors.
Song L, Merceron R, Gracia B, Quintana AL, Risseeuw MDP, Hulpia F, Cos P, Ainsa JA, Munier-Lehmann H, Savvides SN, Van Calenbergh S
J Med Chem. 2018 Apr 12;61(7):2753-2775. Epub 2018 Mar 15.
DOI: 10.1021/ACS.JMEDCHEM.7B01570  |   PUBMED: 29510037  |   IF(2018) = 6.1
PDB [P14]:  5NR7   

80: Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1through DCC.
Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang JH, Meijers R
Neuron. 2018 Mar 21;97(6):1261-1267.e4. Epub2018 Mar 1.
DOI: 10.1016/J.NEURON.2018.02.010  |   PUBMED: 29503192  |   IF(2018) = 14.4
PDB [P14]:  6FKQ   

79: The structure of hydrogenase-2 from Escherichia coli: implications for H2-driven proton pumping.
Beaton SE, Evans RM, Finney AJ, Lamont CM, Armstrong FA, Sargent F, Carr SB
Biochem J. 2018 Apr 16;475(7):1353-1370.
DOI: 10.1042/BCJ20180053  |   PUBMED: 29555844
PDB [P14]:  6EHQ   

78: Epsin and Sla2 form assemblies through phospholipid interfaces.
Garcia-Alai MM, Heidemann J, Skruzny M, Gieras A, Mertens HDT, Svergun DI, Kaksonen M, Uetrecht C, Meijers R
Nat Commun. 2018 Jan 23;9(1):328.
DOI: 10.1038/S41467-017-02443-X  |   PUBMED: 29362354  |   IF(2022) = 14.9
PDB [P14]:  6ENR  5ONF  5ON7   

77: Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23Receptor Enables Recruitment of the Shared Receptor IL-12Rbeta1.
Bloch Y, Bouchareychas L, Merceron R, Skladanowska K, Van den Bossche L, Detry S, Govindarajan S, Elewaut D, Haerynck F, Dullaers M, Adamopoulos IE, Savvides SN
Immunity. 2018 Jan 16;48(1):45-58.e6. Epub2017 Dec 26.
DOI: 10.1016/J.IMMUNI.2017.12.008  |   PUBMED: 29287995  |   IF(2018) = 21.5
PDB [P14]:  5NJD  5MXA  5MZV  5M85   

76: Crystal structure correlations with the intrinsic thermodynamics of humancarbonic anhydrase inhibitor binding.
Smirnov A, Zubriene A, Manakova E, Grazulis S, Matulis D,
PeerJ. 2018 Feb 26;6:e4412. eCollection 2018.
DOI: 10.7717/PEERJ.4412  |   PUBMED: 29503769
PDB [P14]:  5LLP  5MSB  5LLO  5LLG  5LLC  5OGO   

75: Sugar Acetonides are a Superior Motif for Addressing the Large, Solvent-Exposed Ribose-33 Pocket of tRNA-Guanine Transglycosylase.
Movsisyan LD, Schafer E, Nguyen A, Ehrmann FR, Schwab A, Rossolini T, Zimmerli D, Wagner B, Daff H, Heine A, Klebe G, Diederich F,
Chemistry. 2018 Jul 11;24(39):9957-9967.
DOI: 10.1002/chem.201801756  |   PUBMED: 29939431  |   IF(2019) = 4.9
PDB [P14]:  5JSW  5JSV   

Number of publications for 2018: 29


J Appl Crystallogr. 50:1773 2017
DOI: 10.1107/S1600576717014479  |   PUBMED:
PDB [P14]:  5NYV  5O2G   

73: Rat ceruloplasmin: a new labile copper binding site and zinc/copper mosaic.
Samygina VR, Sokolov AV, Bourenkov G, Schneider TR, Anashkin VA, Kozlov SO, Kolmakov NN, Vasilyev VB,
Metallomics. 2017 Dec 1;9(12):1828-1838. Epub 2017 Nov27.
DOI: 10.1039/C7MT00157F  |   PUBMED: 29177316
PDB [P14]:  5N4L  5N2K   

72: A New Potent Inhibitor of Glycogen Phosphorylase Reveals the Basicity of the Catalytic Site.
Mamais M, Degli Esposti A, Kouloumoundra V, Gustavsson T, Monti F, Venturini A, Chrysina ED, Markovitsi D, Gimisis T
Chemistry. 2017 Jul 3;23(37):8800-8805 Epub 2017Jun 19.
DOI: 10.1002/CHEM.201701591  |   PUBMED: 28493496  |   IF(2019) = 4.9
PDB [P14]:  5MEM   

71: Crystal structure and catalytic characterization of the dehydrogenase/reductaseSDR family member 4 (DHRS4) from Caenorhabditis elegans.
Kisiela M, Faust A, Ebert B, Maser E, Scheidig AJ,
FEBS J. 2017 Nov 19.
DOI: 10.1111/FEBS.14337  |   PUBMED: 29151266  |   IF(2018) = 4.7
PDB [P14]:  5OJG  5OJI   

70: Dynamic control of RSK complexes by phosphoswitch-based regulation.
Gogl G, Biri-Kovacs B, Poti AL, Vadaszi H, Szeder B, Bodor A, Schlosser G, Acs A, Turiak L, Buday L, Alexa A, Nyitray L, Remenyi A,
FEBS J. 2017 Oct 30.
DOI: 10.1111/FEBS.14311  |   PUBMED: 29083550  |   IF(2018) = 4.7
PDB [P14]:  5N7D   

69: Mechanistic insights into cyclic peptide generation by DnaE split-inteins throughquantitative and structural investigation.
Kick L, Harteis S, Koch MF, Schneider S,
ChemBioChem. 2017 Sep 15.
DOI: 10.1002/CBIC.201700503  |   PUBMED: 28914478  |   IF(2018) = 2.6
PDB [P14]:  5OL5   

68: Structures of designed armadillo repeat proteins binding to peptides fused toglobular domains.
Hansen S, Kiefer JD, Madhurantakam C, Mittl PRE, Pluckthun A,
Protein Sci. 2017 Jul 10
DOI: 10.1002/PRO.3229  |   PUBMED: 28691351  |   IF(2018) = 2.4
PDB [P14]:  5MFD   

67: Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and KainateReceptors.
Mollerud S, Pinto A, Marconi L, Frydenvang K, Thorsen TS, Laulumaa S, Venskutonyte R, Winther S, Moral AMC, Tamborini L, Conti P, Pickering DS, Kastrup JS
ACS Chem Neurosci. 2017 Jul 21.
DOI: 10.1021/ACSCHEMNEURO.7B00201  |   PUBMED: 28691798  |   IF(2019) = 4.5
PDB [P14]:  5NEB   

66: Lipoxygenase 2 from Cyanothece sp. controls dioxygen insertion by stericshielding and substrate fixation.
Newie J, Neumann P, Werner M, Mata RA, Ficner R, Feussner I
Sci Rep. 2017 May 18;7(1):2069.
DOI: 10.1038/S41598-017-02153-W  |   PUBMED: 28522865  |   IF(2018) = 4.1
PDB [P14]:  5MEG   

65: Charges Shift Protonation: Neutron Diffraction Reveals that Aniline and2-Aminopyridine Become Protonated Upon Binding to Trypsin.
Schiebel J, Gaspari R, Sandner A, Ngo K, Gerber HD, Cavalli A, Ostermann A, Heine A, Klebe G
Angew Chem Int Ed Engl. 2017 Apr 18;56(17):4887-4890. Epub 2017 Mar 28.
DOI: 10.1002/ANIE.201701038  |   PUBMED: 28371253  |   IF(2019) = 13.0
PDB [P14]:  5MN1  5MNC  5MNB  5MON   

64: Core Mediator structure at 3.4 A extends model of transcription initiationcomplex.
Nozawa K, Schneider TR, Cramer P,
Nature. 2017 May 11;545(7653):248-251.
DOI: 10.1038/NATURE22328  |   PUBMED: 28467824  |   IF(2018) = 43.1
PDB [P14]:  5N9J   

ACS Catalysis. 7:1259-1269 (2017)
DOI: 10.1021/ACSCATAL.6B02100  |   PUBMED:   |   IF(2018) = 12.1
PDB [P14]:  5LH9   

62: Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV.
Mickeviciute A, Timm DD, Gedgaudas M, Linkuviene V, Chen Z, Waheed A, Michailoviene V, Zubriene A, Smirnov A, Capkauskaite E, Baranauskiene L, Jachno J, Revuckiene J, Manakova E, Grazulis S, Matuliene J, Di Cera E, Sly WS, Matulis D, ORCID:,
Eur Biophys J. 2017 Oct 3.
DOI: 10.1007/S00249-017-1256-0  |   PUBMED: 28975383
PDB [P14]:  5IPZ   

61: Structural and functional innovations in the real-time evolution of new(betaalpha)8 barrel enzymes.
Newton MS, Guo X, Soderholm A, Nasvall J, Lundstrom P, Andersson DI, Selmer M, Patrick WM
Proc Natl Acad Sci U S A. 2017 May 2;114(18):4727-4732. Epub 2017 Apr 17.
DOI: 10.1073/PNAS.1618552114  |   PUBMED: 28416687  |   IF(2019) = 9.4
PDB [P14]:  5L6U   

60: Functional and structural insight into properdin control of complement alternative pathway amplification.
Pedersen DV, Roumenina L, Jensen RK, Gadeberg TA, Marinozzi C, Picard C, Rybkine T, Thiel S, Sørensen UB, Stover C, Fremeaux-Bacchi V, Andersen GR.
EMBO J. 2017 Apr 13;36(8):1084-1099.
DOI: 10.15252/embj.201696173. Epub 2017 Mar 6.  |   PUBMED: 28264884   |   IF(2018) = 11.2
PDB [P14]:  PDB:   

59: Intrinsic Thermodynamics and Structures of 2,4- and 3,4-Substituted Fluorinated Benzenesulfonamides Binding to
Zubriene A, Smirnov A, Dudutiene V, Timm DD, Matuliene J, Michailoviene V, Zakšauskas A, Manakova E, Gražulis S, Matulis D
Carbonic Anhydrases. ChemMedChem. 2017 Jan 20;12(2):161-176.
DOI: 10.1002/cmdc.201600509. Epub 2016 Dec 21.  |   PUBMED: 28001003.
PDB [P14]:  5E2M  5E2N  5DRS  5DOH   

Number of publications for 2017: 16


58: Structural basis of myelin-associated glycoprotein adhesion and signalling.
Pronker MF, Lemstra S, Snijder J, Heck AJ, Thies-Weesie DM, Pasterkamp RJ, Janssen BJ
Nat Commun. 2016 Dec 6;7:13584.
DOI: 10.1038/NCOMMS13584  |   PUBMED: 27922006  |   IF(2022) = 14.9
PDB [P14]:  5LFU   

57: A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution.
Schubert R, Kapis S, Gicquel Y, Bourenkov G, Schneider TR, Heymann M, Betzel C, Perbandt M
IUCrJ. 2016 Oct 26;3(Pt 6):393-401. eCollection 2016 Nov 1.
DOI: 10.1107/S2052252516016304  |   PUBMED: 27840678  |   IF(2016) = 5.31
PDB [P14]:  5EN4  5M62  5LH7  5EUV  5C9O  5C9L  5LMH  5LN0  5JXQ  5LH6  5LH5  5LH3  5LH1  5LH0  5F5V  5A62  5D4W  5F5T   

56: Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptorGIF.
Felix J, Kandiah E, De Munck S, Bloch Y, van Zundert GC, Pauwels K, Dansercoer A, Novanska K, Read RJ, Bonvin AM, Vergauwen B, Verstraete K, Gutsche I, Savvides SN
Nat Commun. 2016 Nov 7;7:13228.
DOI: 10.1038/NCOMMS13228  |   PUBMED: 27819269  |   IF(2015) = 11.3
PDB [P14]:  5D22  5D28   

55: Robotic QM/MM-driven maturation of antibody combining sites.
Smirnov IV, Golovin AV, Chatziefthimiou SD, Stepanova AV, Peng Y, Zolotareva OI, Belogurov AA Jr, Kurkova IN, Ponomarenko NA, Wilmanns M, Blackburn GM, Gabibov AG, Lerner RA
Sci Adv. 2016 Oct 19;2(10):e1501695. eCollection 2016 Oct.
DOI: 10.1126/SCIADV.1501695  |   PUBMED: 27774510  |   IF(2018) = 12.5
PDB [P14]:  5TJD  6Y1N  5ADO   

54: HU histone-like DNA-binding protein from Thermus thermophilus: structural andevolutionary analyses.
Papageorgiou AC, Adam PS, Stavros P, Nounesis G, Meijers R, Petratos K, Vorgias CE
Extremophiles. 2016 Jun 24.
DOI: 10.1007/S00792-016-0859-1  |   PUBMED: 27342116  |   IF(2014) = 2.34
PDB [P14]:  5EKA   

53: The inhibition mechanism of human 20S proteasomes enables next-generation inhibitor design.
Schrader J, Henneberg F, Mata RA, Tittmann K, Schneider TR, Stark H, Bourenkov G, Chari A
Science. 2016 Aug 5;353(6299):594-8.
DOI: 10.1126/SCIENCE.AAF8993  |   PUBMED: 27493187  |   IF(2015) = 34.6
PDB [P14]:  5LE5  5LF1  5LF0  5LF3  5LF4  5LF6  5LF7  5LEX  5LEY  5LEZ   

52: Crystal Structure of the Vanadate-Inhibited Ca(2+)-ATPase.
Clausen JD, Bublitz M, Arnou B, Olesen C, Andersen JP, Moller JV, Nissen P,
Structure. 2016 Apr 5;24(4):617-23.
DOI: 10.1016/J.STR.2016.02.018  |   PUBMED: 27050689  |   IF(2014) = 5.62
PDB [P14]:  5A3Q   

51: Aurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidases.
Molitor C, Mauracher SG, Rompel A
Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1806-15. Epub 2016 Mar 14.
DOI: 10.1073/PNAS.1523575113  |   PUBMED: 26976571  |   IF(2015) = 9.74
PDB [P14]:  4Z0Y   

50: Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Drebes J, Kunz M, Windshugel B, Kikhney AG, Muller IB, Eberle RJ, Oberthur D, Cang H, Svergun DI, Perbandt M, Betzel C, Wrenger C
Sci Rep. 2016 Mar 10;6:22871.
DOI: 10.1038/SREP22871  |   PUBMED: 26960569  |   IF(2014) = 5.57
PDB [P14]:  5CGA  5CGE   

49: Sleeping Beauty transposase structure allows rational design of hyperactivevariants for genetic engineering.
Voigt F, Wiedemann L, Zuliani C, Querques I, Sebe A, Mates L, Izsvak Z, Ivics Z, Barabas O,
Nat Commun. 2016 Mar 30;7:11126.
DOI: 10.1038/NCOMMS11126  |   PUBMED: 27025571  |   IF(2014) = 11.4
PDB [P14]:  5CR4   

48: Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells.
Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney AG, Koch-Nolte F, Buck F, Perbandt M, Betzel C, Svergun DI, Hentschke M, Aepfelbacher M,
PLoS Pathog. 2016 Jun 14;12(6):e1005660. eCollection 2016 Jun.
DOI: 10.1371/journal.ppat.1005660  |   PUBMED: 27300509  |   IF(2018) = 6.1
PDB [P14]:  4OW2   

47: Structure of NDP-forming Acetyl-CoA synthetase ACD1 reveals a large rearrangementfor phosphoryl transfer.
Weisse RH, Faust A, Schmidt M, Schonheit P, Scheidig AJ
Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):E519-28. Epub 2016 Jan 19.
DOI: 10.1073/PNAS.1518614113  |   PUBMED: 26787904  |   IF(2014) = 9.67
PDB [P14]:  5HBR  4YAK  4XYL  4YB8  4YBZ  4XYM   

46: Comprehensive Structural Characterization of the Bacterial HomospermidineSynthase-an Essential Enzyme of the Polyamine Metabolism.
Krossa S, Faust A, Ober D, Scheidig AJ,
Sci Rep. 2016 Jan 18;6:19501.
DOI: 10.1038/SREP19501  |   PUBMED: 26776105  |   IF(2014) = 5.6
PDB [P14]:  4TVB  4XRG  4XR4  4XQC  4XQE  4XQG   

Number of publications for 2016: 13


45: The large N-terminal region of the Brr2 RNA helicase guides productivespliceosome activation.
Absmeier E, Wollenhaupt J, Mozaffari-Jovin S, Becke C, Lee CT, Preussner M, Heyd F, Urlaub H, Luhrmann R, Santos KF, Wahl MC
Gene Dev. 2015 Dec 15;29(24):2576-87. Epub 2015 Dec4.
DOI: 10.1101/GAD.271528.115  |   PUBMED: 26637280  |   IF(2014) = 12.6
PDB [P14]:  5DCA   

44: Terahertz radiation induces non-thermal structural changes associated with Fröhlich condensation in a protein crystal.
Lundholm IV, Rodilla H, Wahlgren WY, Duelli A, Bourenkov G, Vukusic J, Friedman R, Stake J, Schneider T, Katona G.
Struct Dyn (2015 Sep)2:054702
DOI: 10.1063/1.4931825  |   PUBMED: 26798828
PDB [P14]:  5APC  5APE  5APD  5APF   

Sci Rep. 2015 Nov 13;5:16520.
DOI: 10.1038/srep16520  |   PUBMED: 26563764  |   IF(2014) = 5.6
PDB [P14]:  4WC9  4WDH  4WEX  4WDF  4WDG  4WDA  4WDB  4WBL   

42: Intrinsic thermodynamics of 4-substituted-2,3,5,6-tetrafluorobenzenesulfonamide binding to carbonic anhydrases by isothermal titration calorimetry.
Zubriene A, Smirnoviene J, Smirnov A, Morkunaite V, Michailoviene V, Jachno J, Juozapaitiene V, Norvaisas P, Manakova E, Grazulis S, Matulis D
Biophys Chem. 2015 Oct;205:51-65.
DOI: 10.1016/J.BPC.2015.05.009  |   PUBMED: 26079542
PDB [P14]:  4WUP  4WR7  4WW8  4WW6  4WUQ   

41: High resolution structures of Plasmodium falciparum GST complexes provide novelinsights into the dimer-tetramer transition and a novel ligand-binding site.
Perbandt M,Eberle R,Fischer-Riepe L,Cang H,Liebau E,Betzel C
J Struct Biol. 2015 Sep;191(3):365-75. Epub 2015 Jun 10.
DOI: 10.1016/J.JSB.2015.06.008  |   PUBMED: 26072058  |   IF(2018) = 3.8
PDB [P14]:  4ZXG   

40: Fragment Binding Can Be Either More Enthalpy-Driven or Entropy-Driven: CrystalStructures and Residual Hydration Patterns Suggest Why.
Ruhmann E, Betz M, Heine A, Klebe G
J Med Chem. 2015 Sep 10;58(17):6960-71. Epub2015 Aug 24.
DOI: 10.1021/ACS.JMEDCHEM.5B00812  |   PUBMED: 26270568  |   IF(2014) = 5.5
PDB [P14]:  4UDW  5AHG  5AF9  4UD9   

39: Structural basis of GD2 ganglioside and mimetic peptide recognition by 14G2aantibody.
Horwacik I, Golik P, Grudnik P, Kolinski M, Zdzalik M, Rokita H, Dubin G
Mol Cell Proteomics. 2015 Jul 15.
DOI: 10.1074/mcp.M115.052720  |   PUBMED: 26179345  |   IF(2018) = 4.8
PDB [P14]:  4TUK  4TUO  4TUL  4TRP   

38: Structural analysis of the diadenylate cyclase reaction of DNA-integrity scanningprotein A (DisA) and its inhibition by 3'-dATP.
Muller M, Deimling T, Hopfner KP, Witte G
Biochem J. 2015 Aug 1;469(3):367-74. Epub 2015 May 27.
DOI: 10.1042/BJ20150373  |   PUBMED: 26014055
PDB [P14]:  4YVZ   

37: Natural flavonoids as antidiabetic agents. The binding of gallic and ellagicacids to glycogen phosphorylase b.
Kyriakis E, Stravodimos GA, Kantsadi AL, Chatzileontiadou DS, Skamnaki VT, Leonidas DD
FEBS Lett. 2015 Jul 8;589(15):1787-94. Epub2015 May 14.
DOI: 10.1016/j.febslet.2015.05.013  |   PUBMED: 25980608  |   IF(2018) = 2.7
PDB [P14]:  4Z5X   

36: Architecture of TFIIIC and its role in RNA polymerase III pre-initiation complex assembly.
Male G, von Appen A, Glatt S, Taylor NM, Cristovao M, Groetsch H, Beck M, Muller CW
Nat Commun. 2015 Jun 10;6:7387.
DOI: 10.1038/NCOMMS8387  |   PUBMED: 26060179  |   IF(2014) = 11.4
PDB [P14]:  5AIO   

Acta Crystallogr F Struct Biol Commun. 2015 Apr;71(Pt 4):419-26
DOI: 10.1107/S2053230X15004100  |   PUBMED: 25849503   |   IF(2019) = 0.97
PDB [P14]:  4X7T  4X7S   

34: A covalent homodimer probing early oligomers along amyloid aggregation.
Halabelian L, Relini A, Barbiroli A, Penco A, Bolognesi M, Ricagno S
Sci Rep. 2015 Sep 30;5:14651.
DOI: 10.1038/srep14651  |   PUBMED: 26420657  |   IF(2014) = 5.6
PDB [P14]:  4RA3   

33: Structural Elucidation of the Bispecificity of A Domains as a Basis forActivating Non-natural Amino Acids.
Kaljunen H, Schiefelbein SH, Stummer D, Kozak S, Meijers R, Christiansen G, Rentmeister A
Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8833-6.
DOI: 10.1002/ANGE.201503275  |   PUBMED: 26096082  |   IF(2014) = 11.6
PDB [P14]:  4D4I  4D4H  4D4G  4D56  4D57   

32: Tracing binding modes in hit-to-lead optimization: chameleon-like poses ofaspartic protease inhibitors.
Kuhnert M, Koster H, Bartholomaus R, Park AY, Shahim A, Heine A, Steuber H, Klebe G, Diederich WE
Angew Chem Int Ed Engl. 2015 Feb 23;54(9):2849-53.
DOI: 10.1002/ANIE.201411206  |   PUBMED: 25630461  |   IF(2014) = 11.6
PDB [P14]:  3WZ6   

31: Structural Hot Spots Determine Functional Diversity of the Candida glabrataEpithelial Adhesin Family.
Diderrich R, Kock M, Maestre-Reyna M, Keller P, Steuber H, Rupp S, Essen LO, Mosch HU
J Biol Chem. 2015 Aug 7;290(32):19597-613.
DOI: 10.1074/jbc.M115.655654  |   PUBMED: 26105055  |   IF(2018) = 4.1
PDB [P14]:  4COZ  4COW   

30: Thiosulfate dehydrogenase (TsdA) from Allochromatium vinosum: structural andfunctional insights into thiosulfate oxidation.
Brito JA, Denkmann K, Pereira IA, Archer M, Dahl C
J Biol Chem. 2015 Apr 3;290(14):9222-38.
DOI: 10.1074/JBC.M114.623397  |   PUBMED: 25673691   |   IF(2018) = 4.1
PDB [P14]:  4WQ8  4WQ9   

29: Structure of the Kti11/Kti13 Heterodimer and Its Double Role in Modifications of tRNA and Eukaryotic Elongation Factor 2.
Glatt S, Zabel R, Vonkova I, Kumar A, Netz DJ, Pierik AJ, Rybin V, Lill R, Gavin AC, Balbach J, Breunig KD, Muller CW.
Structure. 2015 Jan 6;23(1):149-60
DOI: 10.1016/J.STR.2014.11.008  |   PUBMED: 25543256   |   IF(2014) = 6.8
PDB [P14]:  4D4O  4D4P   

28: Detailed structure-function correlations of Bacillus subtilis acetolactatesynthase.
Sommer B, von Moeller H, Haack M, Qoura F, Langner C, Bourenkov G, Garbe D, Loll B, Bruck T
ChemBioChem. 2015 Jan 2;16(1):110-8.
DOI: 10.1002/cbic.201402541  |   PUBMED: 25393087  |   IF(3.1) = 2.6
PDB [P14]:  4RJK   

Number of publications for 2015: 18


27: Crystal structure of Bombyx mori lipoprotein 6: comparative structural analysis of the 30-kDa lipoprotein family
Pietrzyk AJ, Bujacz A, Lochynska M, Jaskolski M, Bujacz G
PLoS One. 2014 Nov 7;9(11):e108761
DOI: 10.1371/JOURNAL.PONE.0108761  |   PUBMED: 25379889   |   IF(2018) = 2.8
PDB [P14]:  4PC4   

26: Crystal structure of the rigor-like human non-muscle myosin-2 motor domain.
Munnich S,Pathan-Chhatbar S,Manstein DJ
FEBS Lett. 2014 Dec 20;588(24):4754-60.
DOI: 10.1016/j.febslet.2014.11.007  |   PUBMED: 25451231  |   IF(2018) = 2.7
PDB [P14]:  4PD3   

25: Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HD, Svergun DI, Zhang Y, Wang JH, Meijers R.
The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue.
Neuron. 2014 Aug 20;83(4):839-49
DOI: 10.1016/J.NEURON.2014.07.010  |   PUBMED: 25123307   |   IF(2013) = 16.5
PDB [P14]:  4URT   

24: Salamun J, Kallio JP, Daher W, Soldati-Favre D, Kursula I.
Structure of Toxoplasma gondii coronin, an actin-binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress.
FASEB J. 2014 Aug 11.
DOI: 10.1096/fj.14-252569  |   PUBMED: 25114175
PDB [P14]:  4OZU   

23: Dunne M, Mertens HD, Garefalaki V, Jeffries CM, Thompson A, Lemke EA, Svergun DI, Mayer MJ, Narbad A, Meijers R.
The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor.
PLoS Pathog. 2014 Jul 24;10(7):e1004228.
DOI: 10.1371/journal.ppat.1004228  |   PUBMED: 25058163   |   IF(2013) = 8.7
PDB [P14]:  4CU2   

22: Specific binding of gibberellic acid by Cytokinin-Specific Binding Proteins: a new aspect of plant hormone-binding proteins with the PR-10 fold.
Ruszkowski M, Sliwiak J, Ciesielska A, Barciszewski J, Sikorski M, Jaskolski M.
Acta Crystallogr Sect D. 70: 2032-2041 (2014)
DOI: 10.1107/S1399004714010578  |   PUBMED: 25004979   |   IF(2018) = 3.2
PDB [P14]:  4PSB   

21: Chasing Protons: How Isothermal Titration Calorimetry, Mutagenesis, and pKa Calculations Trace the Locus of Charge in Ligand Binding to a tRNA-Binding Enzyme.
Neeb M1, Czodrowski P, Heine A, Barandun LJ, Hohn C, Diederich F, Klebe G.
J Med Chem. 2014 Jul 10;57(13):5554-65.
DOI: 10.1021/jm500401x  |   PUBMED: 24955548   |   IF(2018) = 6.1
PDB [P14]:  4PUN  4PUM  4PUL   

20: Janke, R., Goerner, C., Hirte, M., Brueck, T., Loll, B
The first structure of a bacterial diterpene cyclase: CotB2
Acta Crystallogr Sect D. D70 (2014)
DOI: 10.1107/S1399004714005513  |   PUBMED: 24914964  |   IF(2018) = 3.2
PDB [P14]:  4OMH  4OMG   

19: Mierzejewska, K., Siwek, W., Czapinska, H., Skowronek, K., Bujnicki, J.M., Bochtler, M.
Structural basis of the methylation specificity of R.DpnI.
Nucleic Acids Res. 42: 8745-8754 (2014)
DOI: 10.1093/nar/gku546  |   PUBMED: 24966351  |   IF(2018) = 11.1
PDB [P14]:  4KYW   

18: Role of kappa -> lambda light-chain constant-domain switch in the structure and functionality of A17 reactibody
N. Ponomarenko, S. D. Chatziefthimiou, I. Kurkova, Yu. Mokrushina, Y. Mokrushina, A. Stepanova, I. Smirnov, M. Avakyan, T. Bobik, A. Mamedov, V. Mitkevich, A. Belogurov Jr, O. S. Fedorova, M. Dubina, A. Golovin, V. Lamzin, A. Friboulet, A. A. Makarov, M. Wilmanns and A. Gabibov
Acta Crystallogr D Biol Crystallogr. (2014) D70:708-719
DOI: 10.1107/S1399004713032446  |   PUBMED: 24598740  |   IF(2018) = 3.2
PDB [P14]:  3ZL4   

17: Serial crystallography on in vivo-grown microcrystals using synchrotron radiation
Gati, C., Bourenkov, G., Klinge, M., Rehders, D., Stellato, F., Oberthuer, D., Yefanov, O., Sommer, B.P., Mogk, S., Duszenko, M. et al. (2014).
IUCrJ. (2014) 1 87-94
DOI: 10.1107/S2052252513033939  |   PUBMED: 25075324   |   IF(2020) = 4
PDB [P14]:  4N4Z   

16: Resolving the activation site of positive regulators in plant phosphoenolpyruvate carboxylase.
Schlieper D, Förster, K, Paulus JK, Groth G
Mol Plant. 7:437-40 (2014)
DOI: 10.1093/mp/sst130  |   PUBMED: 24043710  |   IF(2019) = 10.8
PDB [P14]:  4BXC   

Number of publications for 2014: 12


15: CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis.
Mastny M, Heuck A, Kurzbauer R, Heiduk A, Boisguerin P, Volkmer R, Ehrmann M, Rodrigues CD, Rudner DZ, Clausen T.
Cell. 155:647 (2013).
DOI: 10.1016/j.cell.2013.09.050  |   PUBMED: 24243021  |   IF(2018) = 36.2
PDB [P14]:  4C2G   

14: Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII
Capkauskaite E, Zubriene A, Smirnov A, Torresan J, Kišonaie M, Kazokaite J, Gylyte J, Michailoviene V, Jogaite V, Manakova E, Gražulis S, Tumkevcius S, Matulis D.
Bioorg Med Chem. 21:6937-6947 (2013)
DOI: 10.1016/j.bmc.2013.09.029  |   PUBMED: 24103428  |   IF(2018) = 2.5
PDB [P14]:  4KNN  4KP5   

13: The landscape of cytokinin binding by a plant nodulin.
Ruszkowski M, Szpotkowski K, Sikorski M, Jaskolski M.
Acta Crystallogr D Biol Crystallogr. (2013) 69:2365-80
DOI: 10.1107/S0907444913021975  |   PUBMED: 24311578   |   IF(2018) = 3.2
PDB [P14]:  4GY9   

12: Crystal structure of the 14-subunit RNA polymerase I
Fernandez-Tornero C, Moreno-Morcillo M, Rashid UJ, Taylor NM, Ruiz FM, Gruene T, Legrand P, Steuerwald U, Mueller CW.
Nature. 502:644 (2013)
DOI: 10.1038/nature12636  |   PUBMED: 24153184  |   IF(2018) = 43.1
PDB [P14]:  4C3I   

11: Crystal Structure of the Gamma-2 Herpesvirus LANA DNA Binding Domain Identifies Charged Surface Residues Which Impact Viral Latency
Correia B, Cerqueira SA, Beauchemin C, Pires de Miranda M, Li S, Ponnusamy R, Rodrigues L, Schneider TR, Carrondo MA, Kaye KM, Simas JP, McVey CE.
PLoS Pathog. 9(10):e1003673 (2013)
DOI: 10.1371/journal.ppat.1003673  |   PUBMED: 24146618  |   IF(2018) = 6.1
PDB [P14]:  4BLG   

10: Structure of the polypeptide crotamine from the Brazilian rattlesnake Crotalus durissus terrificus.
Coronado MA, Gabdulkhakov A, Georgieva D, Sankaran B, Murakami MT, Arni RK, Betzel C.
Acta Crystallogr D Biol Crystallogr. D69:1958-64 (2013)
DOI: 10.1107/S0907444913018003  |   PUBMED: 24100315  |   IF(2018) = 3.2
PDB [P14]:  4GV5   

9: Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization.
Ariza A, Tanner SJ, Walter CT, Dent KC, Shepherd DA, Wu W, Matthews SV, Hiscox JA, Green TJ, Luo M, Elliott RM, Fooks AR, Ashcroft AE, Stonehouse NJ, Ranson NA, Barr JN, Edwards TA.
Nucleic Acids Res. 2013 41(11):5912
DOI: 10.1093/nar/gkt268  |   PUBMED: 23595147  |   IF(2018) = 11.1
PDB [P14]:  3ZLA   

8: The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry.
Jürgens MC, Vürüs J, Rautureau GJ, Shepherd DA, Pye VE, Muldoon J, Johnson CM, Ashcroft AE, Freund SM, Ferguson N.
Nat Chem Biol. 2013 Sep;9(9):540-7.
DOI: 10.1038/nchembio.1294.  |   PUBMED: 23851574  |   IF(2013) = 13.2
PDB [P14]:  3ZHF   

7: Crystallographic analysis of the reaction cycle of 2',3'-cyclic nucleotide 3'-phosphodiesterase, a unique member of the 2H phosphoesterase family
Myllykoski M, Raasakka A, Lehtimäki M, Han H, Kursula I, Kursula P.
J Mol Biol. 425:4307-22 (2013)
DOI: 10.1016/j.jmb.2013.06.012  |   PUBMED: 23831225  |   IF(2018) = 5.1
PDB [P14]:  2YPC   

6: Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann C C, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner K P
Nature. 2013 498:332-337
DOI: 10.1038/nature12305  |   PUBMED: 23722159  |   IF(2014) = 41.4
PDB [P14]:  4KB6   

5: Greater efficiency of photosynthetic carbon fixation due to single amino-acid substitution.
Paulus JK, Schlieper D, Groth G.
Nat Commun. 4:1518 (2013)
DOI: 10.1038/ncomms2504  |   PUBMED: 23443546  |   IF(2013) = 10.2
PDB [P14]:  3ZGB   

4: The crystal structure of Sporosarcina pasteurii urease in a complex with citrate provides new hints for inhibitor design
Benini S, Kosikowska P, Cianci M, Mazzei L, Vara AG, Berlicki , Ciurli S
J Biol Inorg Chem. 2013 Mar;18(3):391-9.
DOI: 10.1007/s00775-013-0983-7  |   PUBMED: 23412551  |   IF(2018) = 3.6
PDB [P14]:  4AC7   

3: A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors.
Malvezzi F, Litos G, Schleiffer A, Heuck A, Mechtler K, Clausen T, Westermann S.
EMBO J. 2013 Feb 6;32(3):409-23.
DOI: 10.1038/emboj.2012.356  |   PUBMED: 23334295  |   IF(2018) = 11.2
PDB [P14]:  4GEQ   

Number of publications for 2013: 13


2: Structural basis for cooperativity of CRM1 export complex formation.
Monecke T, Haselbach D, VoßB, Russek A, Neumann P, Thomson E, Hurt E, Zachariae U, Stark H, Grubmüller H, Dickmanns A, Ficner R.
Proc Natl Acad Sci U S A. 2012 Dec 31. [Epub ahead of print]
DOI: 10.1073/pnas.1215214110  |   PUBMED: 23277578  |   IF(2019) = 9.4
PDB [P14]:  4HZK   

1: Structural basis for functional cooperation between tandem helicase cassettes in Brr2-mediated remodeling of the spliceosome.
Santos KF, Jovin SM, Weber G, Pena V, Lührmann R, Wahl MC
Proc Natl Acad Sci U S A. (2012) Oct 23;109(43):17418-23. Epub 2012 Oct 8.
DOI: 10.1073/nas.1208098109  |   PUBMED: 23045696  |   IF(2019) = 9.4
PDB [P14]:  4F91