Research

Software development

Automated building and refinement of macromolecular crystal structures

Subtleties of Enzymatic Reactions

Seeing electron in ultra-high resolution macromolecular crystal structures


Research report 2003 (Crystallography at (sub) atomic resolution and quantum chemistry, ARP/wARP software Version 6.0 and future plans, Modelling crystal contacts by site-directed mutagenesis)

Research report 2002 (Trypsin revisited at ultra high resolution, Current status of the ARP/wARP development, Towards automatic modelling of bound ligands in electron density maps)

Research report 2001 (Enzymatic activation of NADH, MAD at atomic resolution, Automated crystallographic data analysis with ARP/wARP)

Research report 2000 (Valence electron distribution in a protein, Substrate specificity of alcohol dehydrogenase, On the catalysis of D-lactate dehydrogenase, Automated crystallographic data analysis with ARP/wARP)

Research report 1999 (Protein titration in the crystal state Crystal structure of a glutamic acid specific serine protease The ARP/wARP suite for automated building and refinement of macromolecular crystal structures)