AlphaPulldown

AlphaPulldown, a Python package that streamlines protein-protein interaction screens and high-throughput modelling of higher-order oligomers using AlphaFold-Multimer. It provides a convenient command line interface, a variety of confidence scores, and a graphical analysis tool.

Code

• AlphaPulldown source code and installation instructions

Tutorials

• Example 1
• Example 2

How to cite

If you use this software, please cite it along the dependencies it uses internally, at least:

• Yu,D. et al. (2022) AlphaPulldown – a Python package for protein-protein interaction screens using AlphaFold-Multimer. Bioinformatics, Volume 39, Issue 1, January 2023, btac749
• Jumper,J. et al. (2021) Highly accurate protein structure prediction with AlphaFold. Nature 2021 596:7873, 596, 583–589.
• Evans,R. et al. (2022) Protein complex prediction with AlphaFold-Multimer.

Contact:

Please do not hesitate to send requests, comments and bug reports to:
Jan Kosinski: jan.kosinski@embl.de
Dingquan Yu: dingquan.yu@embl-hamburg.de