At EMBL, many groups incorporate different areas of Chemistry into their research, such as chemical synthesis, spectroscopic and spectrometric methods, chemoinformatics, chemical docking and modeling, protein semisynthesis and engineering, as well as analytical and medicinal chemistry. Chemistry often enables an understanding of biological phenomenona that are difficult to approach in a different way. Therefore, EMBL offers the unique opportunity to be involved in development and application of chemical tools (of whichever nature) to answer biological questions. Applications range from deciphering signaling pathways and ligand-macromolecule interactions to drug discovery, to name a few.