EMBL Hamburg, Notkestraße 85, 22607 Hamburg, Germany

Phone: +49(0)4089902-131


Total: 14 publication(s)


Beckham KSH, Staack S, Wilmanns M, Parret AHA. (2020)

The pMy vector series: a versatile cloning platform for the recombinant production of mycobacterial proteins in Mycobacterium smegmatis.

Protein Sci 29(12):2528-2537. doi: 10.1002/pro.3962
Europe PMC | doi


Crosskey TD, Beckham KSH, Wilmanns M. (2019)

The ATPases of the mycobacterial type VII secretion system: structural and mechanistic insights into secretion.

Prog. Biophys. Mol. Biol. 152:25-34. doi: 10.1016/j.pbiomolbio.2019.11.008
Europe PMC | doi

Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Schnappinger D, Svergun DI, Schneider TR, Genevaux P, de Carvalho LPS, Wilmanns M, Parret AHA, Neyrolles O. (2019)

An NAD+ phosphorylase toxin triggers Mycobacterium tuberculosis cell death.

Mol Cell 73(6):1282-1291. doi: 10.1016/j.molcel.2019.01.028
Europe PMC | doi


Beckham KS, Ciccarelli L, Bunduc CM, Mertens HD, Ummels R, Lugmayr W, Mayr J, Rettel M, Savitski MM, Svergun DI, Bitter W, Wilmanns M, Marlovits TC, Parret AH, Houben EN. (2017)

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis.

Nat Microbiol 2(6):17047. doi: 10.1038/nmicrobiol.2017.47
Europe PMC | doi


Scott CL, Tfp ZM, Beckham KS, Douce G. (2014)

Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103(+) CD11b(+) DCs in the intestinal lamina propria.

Eur. J. Immunol. 44(12):3658-3668. doi: 10.1002/eji.201444859
Europe PMC | doi

Beckham KS, Roe AJ. (2014)

From screen to target: insights and approaches for the development of anti-virulence compounds.

Front Cell Infect Microbiol 4 doi: 10.3389/fcimb.2014.00139
Europe PMC | doi

Beckham KS, Connolly JP, Ritchie JM, Wang D, Gawthorne JA, Tahoun A, Gally DL, Burgess K, Burchmore RJ, Smith BO, Beatson SA, Byron O, Wolfe AJ, Douce GR. (2014)

The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7.

Mol. Microbiol. 93(1):199-211. doi: 10.1111/mmi.12651
Europe PMC | doi


Gabrielsen M, Beckham KS, Feher VA, Zetterström CE, Wang D, Müller S, Elofsson M, Amaro RE, Byron O. (2012)

Structural characterisation of Tpx from Yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds.

PLoS ONE 7(2) doi: 10.1371/journal.pone.0032217
Europe PMC | doi

Gawthorne JA, Reddick LE, Akpunarlieva SN, Beckham KS, Christie JM, Alto NM, Gabrielsen M. (2012)

Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification.

PLoS ONE 7(12) doi: 10.1371/journal.pone.0052962
Europe PMC | doi

Beckham KS, Byron O, Roe AJ. (2012)

The structure of an orthorhombic crystal form of a 'forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 68(Pt 5):522-526. doi: 10.1107/s1744309112011487
Europe PMC | doi

Gabrielsen M, Beckham KS, Cogdell RJ, Byron O. (2012)

FolX from Pseudomonas aeruginosa is octameric in both crystal and solution.

FEBS Lett. 586(8):1160-1165. doi: 10.1016/j.febslet.2012.03.031
Europe PMC | doi


Wang D, Zetterström CE, Gabrielsen M, Beckham KS, Tree JJ, Macdonald SE, Byron O, Mitchell TJ, Gally DL, Herzyk P, Mahajan A, Uvell H, Burchmore R, Smith BO, Elofsson M. (2011)

Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds.

J. Biol. Chem. 286(34):29922-29931. doi: 10.1074/jbc.m111.233858
Europe PMC | doi


Gabrielsen M, Zetterström CE, Wang D, Beckham KS, Elofsson M, Isaacs NW. (2010)

Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis.

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66(Pt 12):1606-1609. doi: 10.1107/s1744309110039679
Europe PMC | doi

Beckham KS, Potter JA. (2010)

Formate-nitrite transporters: optimisation of expression, purification and analysis of prokaryotic and eukaryotic representatives.

Protein Expr. Purif. 71(2):184-189. doi: 10.1016/j.pep.2009.12.005
Europe PMC | doi