Location & dates EMBL Hamburg, Germany 7 - 9 Oct 2019
Deadlines Registration closed Abstract submission closed

EMBL Courses and Conferences during the Coronavirus pandemic

With the onsite programme paused, many of our events are now being offered in virtual formats.

Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.

More information for participants of events at EMBL Heidelberg can be found here.

The final programme, poster listing and onsite handout with logistical information are now available for download.

Conference Overview

Integral membrane proteins (IMPs) are encoded by 20-30 % of genes in a genome and provide key functions in the cell. Due to their hydrophobic nature, they are structurally and biochemically difficult to study. Traditionally, IMPs have been extracted using detergents which are a poor mimic of the lipid membrane and have been shown to denature membrane proteins. However, newly developed lipid-nanodisc approaches enable structural and functional studies of IMPs in a detergent-free, near-native membrane environment. Recent studies have also focused on further developments of novel membrane mimetics including novel expression and stabilisation strategies to overcome the remaining methodological challenges posed by avariety of IMPs. These technologies have delivered fascinating new insights into membrane protein structure, dynamics and function within the last years. This conference will bring together researchers developing and applying these new methodologies. In addition to providing a forum to exchange the latest developments in the field, the conference provides excellent opportunities for early-career scientist in the field to learn all aspects of a variety of tools to study the structure and function of membrane proteins.

Session Topics

  • Membrane mimetics for biochemistry and biophysics
  • Structure, dynamics and folding of MPs in discs
  • MP structure and biophysics
  • Novel membrane tools for structural biology
  • Scattering methods on MPs
  • Drug design and function
  • Production and reconstitution of MPs
  • Structure and of function of MPs