EMBL Hamburg, Notkestraße 85, 22607 Hamburg, Germany


  • PhD, 1990, University of Basel, Switzerland.
    Postdoctoral research at the University of California, Los Angeles, USA, and at EMBL Heidelberg, Germany.
    Group leader, Senior Scientist, and Head of EMBL Hamburg since 1997.
    Research Director of the Center for Structural Systems Biology (CSSB) 2014 - 2017.
    Professor at the University Hamburg Clinical Center Eppendorf (UKE) since 2015.


Total: 189 publication(s)


Neufeld C, Filipp FV, Simon B, Neuhaus A, Schüller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M. (2009)

Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19

EMBO J. 28(6):745-754. doi: 10.1038/emboj.2009.7
Europe PMC | doi

Stacklies W, Vega MC, Wilmanns M, Gräter F. (2009)

Mechanical network in titin immunoglobulin from force distribution analysis

PLoS Comput. Biol. 5(3):e1000306. doi: 10.1371/journal.pcbi.1000306
Europe PMC | doi

Pinotsis N, Abrusci P, Djinović-Carugo K, Wilmanns M. (2009)

Terminal assembly of sarcomeric filaments by intermolecular beta-sheet formation

Trends Biochem. Sci. 34(1):33-39. doi: 10.1016/j.tibs.2008.09.009
Europe PMC | doi

Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R. (2009)

Crystal structure of the resuscitation-promoting factor (DeltaDUF)RpfB from M. tuberculosis

J. Mol. Biol. 385(1):153-162. doi: 10.1016/j.jmb.2008.10.042
Europe PMC | doi


Pinotsis N, Wilmanns M. (2008)

Protein assemblies with palindromic structure motifs

Cell. Mol. Life Sci. 65(19):2953-2956. doi: 10.1007/s00018-008-8265-1
Europe PMC | doi

Lamber EP, Vanhille L, Textor LC, Kachalova GS, Sieweke MH, Wilmanns M. (2008)

Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization

EMBO J. 27(14):2006-2017. doi: 10.1038/emboj.2008.117
Europe PMC | doi

Song YH, Wilmanns M. (2008)

Bimolecular fluorescence complementation in structural biology

Methods 45(3):219-222. doi: 10.1016/j.ymeth.2008.06.015
Europe PMC | doi

Black SL, Stanley WA, Filipp FV, Bhairo M, Verma A, Wichmann O, Sattler M, Wilmanns M, Schultz C. (2008)

Probing lipid- and drug-binding domains with fluorescent dyes

Bioorg. Med. Chem. 16(3):1162-1173. doi: 10.1016/j.bmc.2007.10.080
Europe PMC | doi

Kursula P, Kursula I, Massimi M, Song YH, Downer J, Stanley WA, Witke W, Wilmanns M. (2008)

High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP

J. Mol. Biol. 375(1):270-290. doi: 10.1016/j.jmb.2007.10.050
Europe PMC | doi

Lamber EP, Wilmanns M, Svergun DI. (2008)

Low resolution structural models of the basic helix-loop-helix leucine zipper domain of upstream stimulatory factor 1 and its complexes with DNA from small angle X-ray scattering data

Biophys. J. 94(1):193-197. doi: 10.1529/biophysj.107.112243
Europe PMC | doi

Pinotsis N, Lange S, Perriard JC, Svergun DI, Wilmanns M. (2008)

Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesin

EMBO J. 27(1):253-264. doi: 10.1038/sj.emboj.7601944
Europe PMC | doi


Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R. (2007)

Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63(Pt 10):870-873. doi: 10.1107/s1744309107043217
Europe PMC | doi

Stanley WA, Fodor K, Marti-Renom MA, Schliebs W, Wilmanns M. (2007)

Protein translocation into peroxisomes by ring-shaped import receptors

FEBS Lett. 581(25):4795-4802. doi: 10.1016/j.febslet.2007.09.001
Europe PMC | doi

Margiolaki I, Wright JP, Wilmanns M, Fitch AN, Pinotsis N. (2007)

Second SH3 domain of ponsin solved from powder diffraction

J. Am. Chem. Soc. 129(38):11865-11871. doi: 10.1021/ja073846c
Europe PMC | doi

Holton SJ, Weiss MS, Tucker PA, Wilmanns M. (2007)

Structure-based approaches to drug discovery against tuberculosis

Curr. Protein Pept. Sci. 8(4):365-375. doi: 10.2174/138920307781369445
Europe PMC | doi

Müller S, Lange S, Gautel M, Wilmanns M. (2007)

Rigid conformation of an immunoglobulin domain tandem repeat in the A-band of the elastic muscle protein titin

J. Mol. Biol. 371(2):469-480. doi: 10.1016/j.jmb.2007.05.055
Europe PMC | doi

Textor LC, Wilmanns M, Holton SJ. (2007)

Expression, purification, crystallization and preliminary crystallographic analysis of the mouse transcription factor MafB in complex with its DNA-recognition motif Cmare

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63(Pt 8):657-661. doi: 10.1107/s1744309107031260
Europe PMC | doi

Gehmlich K, Pinotsis N, Hayess K, van der Ven PF, Milting H, El Banayosy A, Körfer R, Wilmanns M, Ehler E, Fürst DO. (2007)

Paxillin and ponsin interact in nascent costameres of muscle cells

J. Mol. Biol. 369(3):665-682. doi: 10.1016/j.jmb.2007.03.050
Europe PMC | doi

Kuper J, Wong TS, Roccatano D, Wilmanns M, Schwaneberg U. (2007)

Understanding a mechanism of organic cosolvent inactivation in heme monooxygenase P450 BM-3

J. Am. Chem. Soc. 129(18):5786-5787. doi: 10.1021/ja067036x
Europe PMC | doi

Stanley WA, Versluis K, Schultz C, Heck AJ, Wilmanns M. (2007)

Investigation of the ligand spectrum of human sterol carrier protein 2 using a direct mass spectrometry assay

Arch. Biochem. Biophys. 461(1):50-58. doi: 10.1016/j.abb.2007.02.026
Europe PMC | doi

Mueller-Dieckmann C, Panjikar S, Schmidt A, Mueller S, Kuper J, Geerlof A, Wilmanns M, Singh RK, Tucker PA, Weiss MS. (2007)

On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths

Acta Crystallogr. D Biol. Crystallogr. 63(Pt 3):366-380. doi: 10.1107/s0907444906055624
Europe PMC | doi

Visser NV, Wang D, Stanley WA, Groves MR, Wilmanns M, Veenhuis M, van der Klei IJ. (2007)

Octameric alcohol oxidase dissociates into stable, soluble monomers upon incubation with dimethylsulfoxide

Arch. Biochem. Biophys. 459(2):208-213. doi: 10.1016/j.abb.2007.01.005
Europe PMC | doi

Stanley WA, Pursiainen NV, Garman EF, Juffer AH, Wilmanns M, Kursula P. (2007)

A previously unobserved conformation for the human Pex5p receptor suggests roles for intrinsic flexibility and rigid domain motions in ligand binding

BMC Struct. Biol. 7:24. doi: 10.1186/1472-6807-7-24
Europe PMC | doi


Holton SJ, King-Scott S, Nasser Eddine A, Kaufmann SH, Wilmanns M. (2006)

Structural diversity in the six-fold redundant set of acyl-CoA carboxyltransferases in Mycobacterium tuberculosis

FEBS Lett. 580(30):6898-6902. doi: 10.1016/j.febslet.2006.11.054
Europe PMC | doi

Stanley WA, Filipp FV, Kursula P, Schüller N, Erdmann R, Schliebs W, Sattler M, Wilmanns M. (2006)

Recognition of a functional peroxisome type 1 target by the dynamic import receptor pex5p

Mol. Cell 24(5):653-663. doi: 10.1016/j.molcel.2006.10.024
Europe PMC | doi

Stanley WA, Wilmanns M. (2006)

Dynamic architecture of the peroxisomal import receptor Pex5p

Biochim. Biophys. Acta 1763(12):1592-1598. doi: 10.1016/j.bbamcr.2006.10.015
Europe PMC | doi

Alzari PM, Berglund H, Berrow NS, Blagova E, Busso D, Cambillau C, Campanacci V, Christodoulou E, Eiler S, Fogg MJ, Folkers G, Geerlof A, Hart D, Haouz A, Herman MD, Macieira S, Nordlund P, Perrakis A, Quevillon-Cheruel S, Tarandeau F, van Tilbeurgh H, Unger T, Luna-Vargas MP, Velarde M, Willmanns M, Owens RJ. (2006)

Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE

Acta Crystallogr. D Biol. Crystallogr. 62(Pt 10):1103-1113. doi: 10.1107/s0907444906029775
Europe PMC | doi

Fogg MJ, Alzari P, Bahar M, Bertini I, Betton JM, Burmeister WP, Cambillau C, Canard B, Corrondo MA, Coll M, Daenke S, Dym O, Egloff MP, Enguita FJ, Geerlof A, Haouz A, Jones TA, Ma Q, Manicka SN, Migliardi M, Nordlund P, Owens RJ, Peleg Y, Schneider G, Schnell R, Stuart DI, Tarbouriech N, Unge T, Wilkinson AJ, Wilmanns M, Wilson KS, Zimhony O, Grimes JM. (2006)

Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens

Acta Crystallogr. D Biol. Crystallogr. 62(Pt 10):1196-1207. doi: 10.1107/s0907444906030915
Europe PMC | doi

Geerlof A, Brown J, Coutard B, Egloff MP, Enguita FJ, Fogg MJ, Gilbert RJ, Groves MR, Haouz A, Nettleship JE, Nordlund P, Owens RJ, Ruff M, Sainsbury S, Svergun DI, Wilmanns M. (2006)

The impact of protein characterization in structural proteomics

Acta Crystallogr. D Biol. Crystallogr. 62(Pt 10):1125-1136. doi: 10.1107/s0907444906030307
Europe PMC | doi

Maier S, Staffler G, Hartmann A, Höck J, Henning K, Grabusic K, Mailhammer R, Hoffmann R, Wilmanns M, Lang R, Mages J, Kempkes B. (2006)

Cellular target genes of Epstein-Barr virus nuclear antigen 2

J. Virol. 80(19):9761-9771. doi: 10.1128/jvi.00665-06
Europe PMC | doi

Marino M, Zou P, Svergun D, Garcia P, Edlich C, Simon B, Wilmanns M, Muhle-Goll C, Mayans O. (2006)

The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin

Structure 14(9):1437-1447. doi: 10.1016/j.str.2006.07.009
Europe PMC | doi

Pinotsis N, Petoukhov M, Lange S, Svergun D, Zou P, Gautel M, Wilmanns M. (2006)

Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus

Paper presented at the 4th Workshop on Coiled Coils, Collagen and Co-Proteins, Alpbach, AUSTRIA, SEP 11-17, 2005.J. Struct. Biol. 155(2):239-250. doi: 10.1016/j.jsb.2006.03.028
Europe PMC | doi

Giastas P, Pinotsis N, Efthymiou G, Wilmanns M, Kyritsis P, Moulis JM, Mavridis IM. (2006)

The structure of the 2[4Fe-4S] ferredoxin from Pseudomonas aeruginosa at 1.32-A resolution: comparison with other high-resolution structures of ferredoxins and contributing structural features to reduction potential values

J. Biol. Inorg. Chem. 11(4):445-458. doi: 10.1007/s00775-006-0094-9
Europe PMC | doi

Ma Q, Zhao X, Nasser Eddine A, Geerlof A, Li X, Cronan JE, Kaufmann SH, Wilmanns M. (2006)

The Mycobacterium tuberculosis LipB enzyme functions as a cysteine/lysine dyad acyltransferase

Proc. Natl. Acad. Sci. U.S.A. 103(23):8662-8667. doi: 10.1073/pnas.0510436103
Europe PMC | doi

Mueller-Dieckmann H-J, Weiss MS, Wilmanns M. (2006)

Protein crystallization for X-ray

Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine.Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine 1478-1482. doi: 10.1007/3-540-29623-9_5060

Lee EH, Gao M, Pinotsis N, Wilmanns M, Schulten K. (2006)

Mechanical strength of the titin Z1Z2-telethonin complex

Structure 14(3):497-509. doi: 10.1016/j.str.2005.12.005
Europe PMC | doi

Müller S, Kursula I, Zou P, Wilmanns M. (2006)

Crystal structure of the PB1 domain of NBR1

FEBS Lett. 580(1):341-344. doi: 10.1016/j.febslet.2005.12.021
Europe PMC | doi

Zou P, Pinotsis N, Lange S, Song YH, Popov A, Mavridis I, Mayans OM, Gautel M, Wilmanns M. (2006)

Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk

Nature 439(7073):229-233. doi: 10.1038/nature04343
Europe PMC | doi


Kim C, Gajendran N, Mittrücker HW, Weiwad M, Song YH, Hurwitz R, Wilmanns M, Fischer G, Kaufmann SH. (2005)

Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences

Proc. Natl. Acad. Sci. U.S.A. 102(13):4830-4835. doi: 10.1073/pnas.0500508102
Europe PMC | doi

Kuper J, Doenges C, Wilmanns M. (2005)

Two-fold repeated (betaalpha)4 half-barrels may provide a molecular tool for dual substrate specificity

EMBO Rep. 6(2):134-139. doi: 10.1038/sj.embor.7400330
Europe PMC | doi

Vega MC, Zou P, Fernandez FJ, Murphy GE, Sterner R, Popov A, Wilmanns M. (2005)

Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like subunit

Mol. Microbiol. 55(3):675-686. doi: 10.1111/j.1365-2958.2004.04422.x
Europe PMC | doi

Wilmanns M, Weiss MS. (2005)

Molecular crystallography

In: Bassani, F; Liedl, GL;Wyder P, Encyclopedia of Condensed Matter Physics. Elsevier . pp 453-458.doi: 10.1016/b0-12-369401-9/00424-1
Europe PMC | doi


Stanley WA, Sokolova A, Brown A, Clarke DT, Wilmanns M, Svergun DI. (2004)

Synergistic use of synchrotron radiation techniques for biological samples in solution: a case study on protein-ligand recognition by the peroxisomal import receptor Pex5p

J Synchrotron Radiat 11(Pt 6):490-496. doi: 10.1107/s090904950402504x
Europe PMC | doi

Barabás O, Pongrácz V, Kovári J, Wilmanns M, Vértessy BG. (2004)

Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase

J. Biol. Chem. 279(41):42907-42915. doi: 10.1074/jbc.m406135200
Europe PMC | doi

Reményi A, Schöler HR, Wilmanns M. (2004)

Combinatorial control of gene expression

Nat. Struct. Mol. Biol. 11(9):812-815. doi: 10.1038/nsmb820
Europe PMC | doi

Fernandez FJ, Vega MC, Lehmann F, Sandmeier E, Gehring H, Christen P, Wilmanns M. (2004)

Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase

J. Biol. Chem. 279(20):21478-21488. doi: 10.1074/jbc.m400291200
Europe PMC | doi

Fernández-Escamilla AM, Cheung MS, Vega MC, Wilmanns M, Onuchic JN, Serrano L. (2004)

Solvation in protein folding analysis: combination of theoretical and experimental approaches

Proc. Natl. Acad. Sci. U.S.A. 101(9):2834-2839. doi: 10.1073/pnas.0304180101
Europe PMC | doi

Linden A, Wilmanns M. (2004)

Adaptation of class-13 alpha-amylases to diverse living conditions

Paper presented at the 86th International Titisee Conference, Titisee, GERMANY, OCT 23-27, 2002.Chembiochem 5(2):231-239. doi: 10.1002/cbic.200300734
Europe PMC | doi


Vega MC, Lorentzen E, Linden A, Wilmanns M. (2003)

Evolutionary markers in the (beta/alpha)8-barrel fold

Curr Opin Chem Biol 7(6):694-701. doi: 10.1016/j.cbpa.2003.10.004
Europe PMC | doi

Reményi A, Lins K, Nissen LJ, Reinbold R, Schöler HR, Wilmanns M. (2003)

Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers

Genes Dev. 17(16):2048-2059. doi: 10.1101/gad.269303
Europe PMC | doi

Lins K, Reményi A, Tomilin A, Massa S, Wilmanns M, Matthias P, Schöler HR. (2003)

OBF1 enhances transcriptional potential of Oct1

EMBO J. 22(9):2188-2198. doi: 10.1093/emboj/cdg199
Europe PMC | doi

Linden A, Mayans O, Meyer-Klaucke W, Antranikian G, Wilmanns M. (2003)

Differential regulation of a hyperthermophilic alpha-amylase with a novel (Ca,Zn) two-metal center by zinc

J. Biol. Chem. 278(11):9875-9884. doi: 10.1074/jbc.m211339200
Europe PMC | doi

Terwilliger TC, Park MS, Waldo GS, Berendzen J, Hung LW, Kim CY, Smith CV, Sacchettini JC, Bellinzoni M, Bossi R, De Rossi E, Mattevi A, Milano A, Riccardi G, Rizzi M, Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP, Goulding CW, Apostol MI, Anderson DH, Gill HS, Eisenberg DS, Taneja B, Mande S, Pohl E, Lamzin V, Tucker P, Wilmanns M, Colovos C, Meyer-Klaucke W, Munro AW, McLean KJ, Marshall KR, Leys D, Yang JK, Yoon HJ, Lee BI, Lee MG, Kwak JE, Han BW, Lee JY, Baek SH, Suh SW, Komen MM, Arcus VL, Baker EN, Lott JS, Jacobs W Jr, Alber T, Rupp B. (2003)

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology

Tuberculosis (Edinb) 83(4):223-249. doi: 10.1016/s1472-9792(03)00051-9
Europe PMC | doi

Zou P, Gautel M, Geerlof A, Wilmanns M, Koch MH, Svergun DI. (2003)

Solution scattering suggests cross-linking function of telethonin in the complex with titin

J. Biol. Chem. 278(4):2636-2644. doi: 10.1074/jbc.m210217200
Europe PMC | doi


Gao M, Wilmanns M, Schulten K. (2002)

Steered molecular dynamics studies of titin I1 domain unfolding

Biophys. J. 83(6):3435-3445. doi: 10.1016/s0006-3495(02)75343-5
Europe PMC | doi

Douangamath A, Filipp FV, Klein AT, Barnett P, Zou P, Voorn-Brouwer T, Vega MC, Mayans OM, Sattler M, Distel B, Wilmanns M. (2002)

Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain

Mol. Cell 10(5):1007-1017. doi: 10.1016/s1097-2765(02)00749-9
Europe PMC | doi

Paavilainen VO, Merckel MC, Falck S, Ojala PJ, Pohl E, Wilmanns M, Lappalainen P. (2002)

Structural conservation between the actin monomer-binding sites of twinfilin and actin-depolymerizing factor (ADF)/cofilin

J. Biol. Chem. 277(45):43089-43095. doi: 10.1074/jbc.m208225200
Europe PMC | doi

Reményi A, Tomilin A, Schöler HR, Wilmanns M. (2002)

Differential activity by DNA-induced quarternary structures of POU transcription factors

Paper presented at the Meeting on Cell Signaling Transcription and Translation as Therapeutic Targets, LUXEMBOURG, GERMANY, JAN 30-FEB 02, 2002.Biochem. Pharmacol. 64(5-6):979-984. doi: 10.1016/s0006-2952(02)01164-4
Europe PMC | doi

Mayans O, Ivens A, Nissen LJ, Kirschner K, Wilmanns M. (2002)

Structural analysis of two enzymes catalysing reverse metabolic reactions implies common ancestry

EMBO J. 21(13):3245-3254. doi: 10.1093/emboj/cdf298
Europe PMC | doi

Pohl E, Brunner N, Wilmanns M, Hensel R. (2002)

The crystal structure of the allosteric non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeum Thermoproteus tenax

J. Biol. Chem. 277(22):19938-19945. doi: 10.1074/jbc.m112244200
Europe PMC | doi

Fazi B, Cope MJ, Douangamath A, Ferracuti S, Schirwitz K, Zucconi A, Drubin DG, Wilmanns M, Cesareni G, Castagnoli L. (2002)

Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis

J. Biol. Chem. 277(7):5290-5298. doi: 10.1074/jbc.m109848200
Europe PMC | doi

Ivens A, Mayans O, Szadkowski H, Jürgens C, Wilmanns M, Kirschner K. (2002)

Stabilization of a (betaalpha)8-barrel protein by an engineered disulfide bridge

Eur. J. Biochem. 269(4):1145-1153. doi: 10.1046/j.1432-1033.2002.02745.x
Europe PMC | doi

Wilmanns M. (2002)

Integrated structural genomics in Europe

Gene Funct. Dis. 3(1-2):18-24.
Europe PMC

Wilmanns M. (2002)

Structural genomics in Europe and beyond - Shifting scientific directions at EMBL Hamburg

Acta Physica Polonica A 101(5):635-646.
Europe PMC


Reményi A, Pohl E, Schöler HR, Wilmanns M. (2001)

Crystallization of redox-insensitive Oct1 POU domain with different DNA-response elements

Acta Crystallogr. D Biol. Crystallogr. 57(Pt 11):1634-1638. doi: 10.1107/s090744490101099x
Europe PMC | doi

Henn-Sax M, Höcker B, Wilmanns M, Sterner R. (2001)

Divergent evolution of (betaalpha)8-barrel enzymes

Biol. Chem. 382(9):1315-1320. doi: 10.1515/bc.2001.163
Europe PMC | doi

Reményi A, Tomilin A, Pohl E, Lins K, Philippsen A, Reinbold R, Schöler HR, Wilmanns M. (2001)

Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping

Mol. Cell 8(3):569-580. doi: 10.1016/s1097-2765(01)00336-7
Europe PMC | doi

Wilmanns M. (2001)

Matti Saraste (1949-2001)

Structure 9(9):769-770. doi: 10.1016/s0969-2126(01)00650-5
Europe PMC | doi

Höcker B, Jürgens C, Wilmanns M, Sterner R. (2001)

Stability, catalytic versatility and evolution of the (beta alpha)(8)-barrel fold

Curr. Opin. Biotechnol. 12(4):376-381. doi: 10.1016/s0958-1669(00)00230-5
Europe PMC | doi

Ivens A, Mayans O, Szadkowski H, Wilmanns M, Kirschner K. (2001)

Purification, characterization and crystallization of thermostable anthranilate phosphoribosyltransferase from Sulfolobus solfataricus

Eur. J. Biochem. 268(8):2246-2252. doi: 10.1046/j.1432-1327.2001.02102.x
Europe PMC | doi

Mayans O, Wuerges J, Canela S, Gautel M, Wilmanns M. (2001)

Structural evidence for a possible role of reversible disulphide bridge formation in the elasticity of the muscle protein titin

Structure 9(4):331-340. doi: 10.1016/s0969-2126(01)00591-3
Europe PMC | doi

Berisio R, Viguera A, Serrano L, Wilmanns M. (2001)

Atomic resolution structure of a mutant of the spectrin SH3 domain

Acta Crystallogr. D Biol. Crystallogr. 57(Pt 2):337-340. doi: 10.1107/s090744490001581x
Europe PMC | doi


Tomilin A, Reményi A, Lins K, Bak H, Leidel S, Vriend G, Wilmanns M, Schöler HR. (2000)

Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration

Cell 103(6):853-864. doi: 10.1016/s0092-8674(00)00189-6
Europe PMC | doi

Lang D, Thoma R, Henn-Sax M, Sterner R, Wilmanns M. (2000)

Structural evidence for evolution of the beta/alpha barrel scaffold by gene duplication and fusion

Science 289(5484):1546-1550. doi: 10.1126/science.289.5484.1546
Europe PMC | doi

Jürgens C, Strom A, Wegener D, Hettwer S, Wilmanns M, Sterner R. (2000)

Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways

Proc. Natl. Acad. Sci. U.S.A. 97(18):9925-9930. doi: 10.1073/pnas.160255397
Europe PMC | doi

Wilmann M, Gautel M, Mayans O. (2000)

Activation of calcium/calmodulin regulated kinases

Cell. Mol. Biol. (Noisy-le-grand) 46(5):883-894.
Europe PMC

Wilmanns M, Gautel M. (2000)

Regulation von Proteinkinasen der MLCK-Familie

Biospektrum 5(3):198-201.

Brunner NA, Lang DA, Wilmanns M, Hensel R. (2000)

Crystallization and preliminary X-ray diffraction analysis of the NAD-dependent non--phosphorylating GAPDH of the hyperthermophilic archaeon Thermoproteus tenax

Acta Crystallogr. D Biol. Crystallogr. 56(Pt 1):89-91. doi: 10.1107/s0907444999014134
Europe PMC | doi

Wilmanns M. (2000)

Future structural biology applications with a free-electron laser - more than wild dreams?

J Synchrotron Radiat 7(Pt 1):41-46.
Europe PMC


Knöchel T, Ivens A, Hester G, Gonzalez A, Bauerle R, Wilmanns M, Kirschner K, Jansonius JN. (1999)

The crystal structure of anthranilate synthase from Sulfolobus solfataricus: functional implications

Proc. Natl. Acad. Sci. U.S.A. 96(17):9479-9484. doi: 10.1073/pnas.96.17.9479
Europe PMC | doi

Thoma R, Obmolova G, Lang DA, Schwander M, Jenö P, Sterner R, Wilmanns M. (1999)

Efficient expression, purification and crystallisation of two hyperthermostable enzymes of histidine biosynthesis

FEBS Lett. 454(1-2):1-6. doi: 10.1016/s0014-5793(99)00757-7
Europe PMC | doi

Martínez JC, Viguera AR, Berisio R, Wilmanns M, Mateo PL, Filimonov VV, Serrano L. (1999)

Thermodynamic analysis of alpha-spectrin SH3 and two of its circular permutants with different loop lengths: discerning the reasons for rapid folding in proteins

Biochemistry 38(2):549-559. doi: 10.1021/bi981515u
Europe PMC | doi

Mayans O, Wilmanns M. (1999)

X-ray analysis of protein crystals with thin-plate morphology

J Synchrotron Radiat 6:1016-1020. doi: 10.1107/s0909049599004616
Europe PMC | doi


Mayans O, van der Ven PF, Wilm M, Mues A, Young P, Fürst DO, Wilmanns M, Gautel M. (1998)

Structural basis for activation of the titin kinase domain during myofibrillogenesis

Nature 395(6705):863-869. doi: 10.1038/27603
Europe PMC | doi

Pisabarro MT, Serrano L, Wilmanns M. (1998)

Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions

J. Mol. Biol. 281(3):513-521. doi: 10.1006/jmbi.1998.1932
Europe PMC | doi


Viguera AR, Serrano L, Wilmanns M. (1996)

Different folding transition states may result in the same native structure

Nat. Struct. Biol. 3(10):874-880. doi: 10.1038/nsb1096-874
Europe PMC | doi


Hyvönen M, Macias MJ, Nilges M, Oschkinat H, Saraste M, Wilmanns M. (1995)

Structure of the binding site for inositol phosphates in a PH domain

EMBO J. 14(19):4676-4685. doi: 10.1002/j.1460-2075.1995.tb00149.x
Europe PMC | doi

Wilmanns M, Eisenberg D. (1995)

Inverse protein folding by the residue pair preference profile method: estimating the correctness of alignments of structurally compatible sequences

Protein Eng. 8(7):627-639. doi: 10.1093/protein/8.7.627
Europe PMC | doi


Musacchio A, Saraste M, Wilmanns M. (1994)

High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides

Nat. Struct. Biol. 1(8):546-551. doi: 10.1038/nsb0894-546
Europe PMC | doi