EMBL Hamburg, Notkestraße 85, 22607 Hamburg, Germany
Biography
PhD, 1990, University of Basel, Switzerland.
Postdoctoral research at the University of California, Los Angeles, USA, and at EMBL Heidelberg, Germany.
Group leader, Senior Scientist, and Head of EMBL Hamburg since 1997.
Research Director of the Center for Structural Systems Biology (CSSB) 2014 - 2017.
Professor at the University Hamburg Clinical Center Eppendorf (UKE) since 2015.
Publications
Total: 189 publication(s)
2009
Neufeld C, Filipp FV, Simon B, Neuhaus A, Schüller N, David C, Kooshapur H, Madl T, Erdmann R, Schliebs W, Wilmanns M, Sattler M. (2009)
Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19
EMBO J. 28(6):745-754. doi: 10.1038/emboj.2009.7
Europe PMC | doi
Stacklies W, Vega MC, Wilmanns M, Gräter F. (2009)
Mechanical network in titin immunoglobulin from force distribution analysis
PLoS Comput. Biol. 5(3):e1000306. doi: 10.1371/journal.pcbi.1000306
Europe PMC | doi
Pinotsis N, Abrusci P, Djinović-Carugo K, Wilmanns M. (2009)
Terminal assembly of sarcomeric filaments by intermolecular beta-sheet formation
Trends Biochem. Sci. 34(1):33-39. doi: 10.1016/j.tibs.2008.09.009
Europe PMC | doi
Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R. (2009)
Crystal structure of the resuscitation-promoting factor (DeltaDUF)RpfB from M. tuberculosis
J. Mol. Biol. 385(1):153-162. doi: 10.1016/j.jmb.2008.10.042
Europe PMC | doi
2008
Pinotsis N, Wilmanns M. (2008)
Protein assemblies with palindromic structure motifs
Cell. Mol. Life Sci. 65(19):2953-2956. doi: 10.1007/s00018-008-8265-1
Europe PMC | doi
Lamber EP, Vanhille L, Textor LC, Kachalova GS, Sieweke MH, Wilmanns M. (2008)
Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization
EMBO J. 27(14):2006-2017. doi: 10.1038/emboj.2008.117
Europe PMC | doi
Song YH, Wilmanns M. (2008)
Bimolecular fluorescence complementation in structural biology
Methods 45(3):219-222. doi: 10.1016/j.ymeth.2008.06.015
Europe PMC | doi
Black SL, Stanley WA, Filipp FV, Bhairo M, Verma A, Wichmann O, Sattler M, Wilmanns M, Schultz C. (2008)
Probing lipid- and drug-binding domains with fluorescent dyes
Bioorg. Med. Chem. 16(3):1162-1173. doi: 10.1016/j.bmc.2007.10.080
Europe PMC | doi
Kursula P, Kursula I, Massimi M, Song YH, Downer J, Stanley WA, Witke W, Wilmanns M. (2008)
High-resolution structural analysis of mammalian profilin 2a complex formation with two physiological ligands: the formin homology 1 domain of mDia1 and the proline-rich domain of VASP
J. Mol. Biol. 375(1):270-290. doi: 10.1016/j.jmb.2007.10.050
Europe PMC | doi
Lamber EP, Wilmanns M, Svergun DI. (2008)
Low resolution structural models of the basic helix-loop-helix leucine zipper domain of upstream stimulatory factor 1 and its complexes with DNA from small angle X-ray scattering data
Biophys. J. 94(1):193-197. doi: 10.1529/biophysj.107.112243
Europe PMC | doi
Pinotsis N, Lange S, Perriard JC, Svergun DI, Wilmanns M. (2008)
Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesin
EMBO J. 27(1):253-264. doi: 10.1038/sj.emboj.7601944
Europe PMC | doi
2007
Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R. (2007)
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63(Pt 10):870-873. doi: 10.1107/s1744309107043217
Europe PMC | doi
Stanley WA, Fodor K, Marti-Renom MA, Schliebs W, Wilmanns M. (2007)
Protein translocation into peroxisomes by ring-shaped import receptors
FEBS Lett. 581(25):4795-4802. doi: 10.1016/j.febslet.2007.09.001
Europe PMC | doi
Margiolaki I, Wright JP, Wilmanns M, Fitch AN, Pinotsis N. (2007)
Second SH3 domain of ponsin solved from powder diffraction
J. Am. Chem. Soc. 129(38):11865-11871. doi: 10.1021/ja073846c
Europe PMC | doi
Holton SJ, Weiss MS, Tucker PA, Wilmanns M. (2007)
Structure-based approaches to drug discovery against tuberculosis
Curr. Protein Pept. Sci. 8(4):365-375. doi: 10.2174/138920307781369445
Europe PMC | doi
Müller S, Lange S, Gautel M, Wilmanns M. (2007)
Rigid conformation of an immunoglobulin domain tandem repeat in the A-band of the elastic muscle protein titin
J. Mol. Biol. 371(2):469-480. doi: 10.1016/j.jmb.2007.05.055
Europe PMC | doi
Textor LC, Wilmanns M, Holton SJ. (2007)
Expression, purification, crystallization and preliminary crystallographic analysis of the mouse transcription factor MafB in complex with its DNA-recognition motif Cmare
Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 63(Pt 8):657-661. doi: 10.1107/s1744309107031260
Europe PMC | doi
Gehmlich K, Pinotsis N, Hayess K, van der Ven PF, Milting H, El Banayosy A, Körfer R, Wilmanns M, Ehler E, Fürst DO. (2007)
Paxillin and ponsin interact in nascent costameres of muscle cells
J. Mol. Biol. 369(3):665-682. doi: 10.1016/j.jmb.2007.03.050
Europe PMC | doi
Kuper J, Wong TS, Roccatano D, Wilmanns M, Schwaneberg U. (2007)
Understanding a mechanism of organic cosolvent inactivation in heme monooxygenase P450 BM-3
J. Am. Chem. Soc. 129(18):5786-5787. doi: 10.1021/ja067036x
Europe PMC | doi
Stanley WA, Versluis K, Schultz C, Heck AJ, Wilmanns M. (2007)
Investigation of the ligand spectrum of human sterol carrier protein 2 using a direct mass spectrometry assay
Arch. Biochem. Biophys. 461(1):50-58. doi: 10.1016/j.abb.2007.02.026
Europe PMC | doi
Mueller-Dieckmann C, Panjikar S, Schmidt A, Mueller S, Kuper J, Geerlof A, Wilmanns M, Singh RK, Tucker PA, Weiss MS. (2007)
On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths
Acta Crystallogr. D Biol. Crystallogr. 63(Pt 3):366-380. doi: 10.1107/s0907444906055624
Europe PMC | doi
Visser NV, Wang D, Stanley WA, Groves MR, Wilmanns M, Veenhuis M, van der Klei IJ. (2007)
Octameric alcohol oxidase dissociates into stable, soluble monomers upon incubation with dimethylsulfoxide
Arch. Biochem. Biophys. 459(2):208-213. doi: 10.1016/j.abb.2007.01.005
Europe PMC | doi
Stanley WA, Pursiainen NV, Garman EF, Juffer AH, Wilmanns M, Kursula P. (2007)
A previously unobserved conformation for the human Pex5p receptor suggests roles for intrinsic flexibility and rigid domain motions in ligand binding
BMC Struct. Biol. 7:24. doi: 10.1186/1472-6807-7-24
Europe PMC | doi
2006
Holton SJ, King-Scott S, Nasser Eddine A, Kaufmann SH, Wilmanns M. (2006)
Structural diversity in the six-fold redundant set of acyl-CoA carboxyltransferases in Mycobacterium tuberculosis
FEBS Lett. 580(30):6898-6902. doi: 10.1016/j.febslet.2006.11.054
Europe PMC | doi
Stanley WA, Filipp FV, Kursula P, Schüller N, Erdmann R, Schliebs W, Sattler M, Wilmanns M. (2006)
Recognition of a functional peroxisome type 1 target by the dynamic import receptor pex5p
Mol. Cell 24(5):653-663. doi: 10.1016/j.molcel.2006.10.024
Europe PMC | doi
Stanley WA, Wilmanns M. (2006)
Dynamic architecture of the peroxisomal import receptor Pex5p
Biochim. Biophys. Acta 1763(12):1592-1598. doi: 10.1016/j.bbamcr.2006.10.015
Europe PMC | doi
Alzari PM, Berglund H, Berrow NS, Blagova E, Busso D, Cambillau C, Campanacci V, Christodoulou E, Eiler S, Fogg MJ, Folkers G, Geerlof A, Hart D, Haouz A, Herman MD, Macieira S, Nordlund P, Perrakis A, Quevillon-Cheruel S, Tarandeau F, van Tilbeurgh H, Unger T, Luna-Vargas MP, Velarde M, Willmanns M, Owens RJ. (2006)
Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE
Acta Crystallogr. D Biol. Crystallogr. 62(Pt 10):1103-1113. doi: 10.1107/s0907444906029775
Europe PMC | doi
Fogg MJ, Alzari P, Bahar M, Bertini I, Betton JM, Burmeister WP, Cambillau C, Canard B, Corrondo MA, Coll M, Daenke S, Dym O, Egloff MP, Enguita FJ, Geerlof A, Haouz A, Jones TA, Ma Q, Manicka SN, Migliardi M, Nordlund P, Owens RJ, Peleg Y, Schneider G, Schnell R, Stuart DI, Tarbouriech N, Unge T, Wilkinson AJ, Wilmanns M, Wilson KS, Zimhony O, Grimes JM. (2006)
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens
Acta Crystallogr. D Biol. Crystallogr. 62(Pt 10):1196-1207. doi: 10.1107/s0907444906030915
Europe PMC | doi
Geerlof A, Brown J, Coutard B, Egloff MP, Enguita FJ, Fogg MJ, Gilbert RJ, Groves MR, Haouz A, Nettleship JE, Nordlund P, Owens RJ, Ruff M, Sainsbury S, Svergun DI, Wilmanns M. (2006)
The impact of protein characterization in structural proteomics
Acta Crystallogr. D Biol. Crystallogr. 62(Pt 10):1125-1136. doi: 10.1107/s0907444906030307
Europe PMC | doi
Maier S, Staffler G, Hartmann A, Höck J, Henning K, Grabusic K, Mailhammer R, Hoffmann R, Wilmanns M, Lang R, Mages J, Kempkes B. (2006)
Cellular target genes of Epstein-Barr virus nuclear antigen 2
J. Virol. 80(19):9761-9771. doi: 10.1128/jvi.00665-06
Europe PMC | doi
Marino M, Zou P, Svergun D, Garcia P, Edlich C, Simon B, Wilmanns M, Muhle-Goll C, Mayans O. (2006)
The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin
Structure 14(9):1437-1447. doi: 10.1016/j.str.2006.07.009
Europe PMC | doi
Pinotsis N, Petoukhov M, Lange S, Svergun D, Zou P, Gautel M, Wilmanns M. (2006)
Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus
Paper presented at the 4th Workshop on Coiled Coils, Collagen and Co-Proteins, Alpbach, AUSTRIA, SEP 11-17, 2005.J. Struct. Biol. 155(2):239-250. doi: 10.1016/j.jsb.2006.03.028
Europe PMC | doi
Giastas P, Pinotsis N, Efthymiou G, Wilmanns M, Kyritsis P, Moulis JM, Mavridis IM. (2006)
The structure of the 2[4Fe-4S] ferredoxin from Pseudomonas aeruginosa at 1.32-A resolution: comparison with other high-resolution structures of ferredoxins and contributing structural features to reduction potential values
J. Biol. Inorg. Chem. 11(4):445-458. doi: 10.1007/s00775-006-0094-9
Europe PMC | doi
Ma Q, Zhao X, Nasser Eddine A, Geerlof A, Li X, Cronan JE, Kaufmann SH, Wilmanns M. (2006)
The Mycobacterium tuberculosis LipB enzyme functions as a cysteine/lysine dyad acyltransferase
Proc. Natl. Acad. Sci. U.S.A. 103(23):8662-8667. doi: 10.1073/pnas.0510436103
Europe PMC | doi
Mueller-Dieckmann H-J, Weiss MS, Wilmanns M. (2006)
Protein crystallization for X-ray
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine.Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine 1478-1482. doi: 10.1007/3-540-29623-9_5060
doi
Lee EH, Gao M, Pinotsis N, Wilmanns M, Schulten K. (2006)
Mechanical strength of the titin Z1Z2-telethonin complex
Structure 14(3):497-509. doi: 10.1016/j.str.2005.12.005
Europe PMC | doi
Müller S, Kursula I, Zou P, Wilmanns M. (2006)
Crystal structure of the PB1 domain of NBR1
FEBS Lett. 580(1):341-344. doi: 10.1016/j.febslet.2005.12.021
Europe PMC | doi
Zou P, Pinotsis N, Lange S, Song YH, Popov A, Mavridis I, Mayans OM, Gautel M, Wilmanns M. (2006)
Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk
Nature 439(7073):229-233. doi: 10.1038/nature04343
Europe PMC | doi
2005
Kim C, Gajendran N, Mittrücker HW, Weiwad M, Song YH, Hurwitz R, Wilmanns M, Fischer G, Kaufmann SH. (2005)
Human alpha-defensins neutralize anthrax lethal toxin and protect against its fatal consequences
Proc. Natl. Acad. Sci. U.S.A. 102(13):4830-4835. doi: 10.1073/pnas.0500508102
Europe PMC | doi
Kuper J, Doenges C, Wilmanns M. (2005)
Two-fold repeated (betaalpha)4 half-barrels may provide a molecular tool for dual substrate specificity
EMBO Rep. 6(2):134-139. doi: 10.1038/sj.embor.7400330
Europe PMC | doi
Vega MC, Zou P, Fernandez FJ, Murphy GE, Sterner R, Popov A, Wilmanns M. (2005)
Regulation of the hetero-octameric ATP phosphoribosyl transferase complex from Thermotoga maritima by a tRNA synthetase-like subunit
Mol. Microbiol. 55(3):675-686. doi: 10.1111/j.1365-2958.2004.04422.x
Europe PMC | doi
Wilmanns M, Weiss MS. (2005)
Molecular crystallography
In: Bassani, F; Liedl, GL;Wyder P, Encyclopedia of Condensed Matter Physics. Elsevier
. pp 453-458.doi: 10.1016/b0-12-369401-9/00424-1
Europe PMC | doi
2004
Stanley WA, Sokolova A, Brown A, Clarke DT, Wilmanns M, Svergun DI. (2004)
Synergistic use of synchrotron radiation techniques for biological samples in solution: a case study on protein-ligand recognition by the peroxisomal import receptor Pex5p
J Synchrotron Radiat 11(Pt 6):490-496. doi: 10.1107/s090904950402504x
Europe PMC | doi
Barabás O, Pongrácz V, Kovári J, Wilmanns M, Vértessy BG. (2004)
Structural insights into the catalytic mechanism of phosphate ester hydrolysis by dUTPase
J. Biol. Chem. 279(41):42907-42915. doi: 10.1074/jbc.m406135200
Europe PMC | doi
Reményi A, Schöler HR, Wilmanns M. (2004)
Combinatorial control of gene expression
Nat. Struct. Mol. Biol. 11(9):812-815. doi: 10.1038/nsmb820
Europe PMC | doi
Fernandez FJ, Vega MC, Lehmann F, Sandmeier E, Gehring H, Christen P, Wilmanns M. (2004)
Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase
J. Biol. Chem. 279(20):21478-21488. doi: 10.1074/jbc.m400291200
Europe PMC | doi
Fernández-Escamilla AM, Cheung MS, Vega MC, Wilmanns M, Onuchic JN, Serrano L. (2004)
Solvation in protein folding analysis: combination of theoretical and experimental approaches
Proc. Natl. Acad. Sci. U.S.A. 101(9):2834-2839. doi: 10.1073/pnas.0304180101
Europe PMC | doi
Linden A, Wilmanns M. (2004)
Adaptation of class-13 alpha-amylases to diverse living conditions
Paper presented at the 86th International Titisee Conference, Titisee, GERMANY, OCT 23-27, 2002.Chembiochem 5(2):231-239. doi: 10.1002/cbic.200300734
Europe PMC | doi
2003
Vega MC, Lorentzen E, Linden A, Wilmanns M. (2003)
Evolutionary markers in the (beta/alpha)8-barrel fold
Curr Opin Chem Biol 7(6):694-701. doi: 10.1016/j.cbpa.2003.10.004
Europe PMC | doi
Reményi A, Lins K, Nissen LJ, Reinbold R, Schöler HR, Wilmanns M. (2003)
Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers
Genes Dev. 17(16):2048-2059. doi: 10.1101/gad.269303
Europe PMC | doi
Lins K, Reményi A, Tomilin A, Massa S, Wilmanns M, Matthias P, Schöler HR. (2003)
OBF1 enhances transcriptional potential of Oct1
EMBO J. 22(9):2188-2198. doi: 10.1093/emboj/cdg199
Europe PMC | doi
Linden A, Mayans O, Meyer-Klaucke W, Antranikian G, Wilmanns M. (2003)
Differential regulation of a hyperthermophilic alpha-amylase with a novel (Ca,Zn) two-metal center by zinc
J. Biol. Chem. 278(11):9875-9884. doi: 10.1074/jbc.m211339200
Europe PMC | doi
Terwilliger TC, Park MS, Waldo GS, Berendzen J, Hung LW, Kim CY, Smith CV, Sacchettini JC, Bellinzoni M, Bossi R, De Rossi E, Mattevi A, Milano A, Riccardi G, Rizzi M, Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP, Goulding CW, Apostol MI, Anderson DH, Gill HS, Eisenberg DS, Taneja B, Mande S, Pohl E, Lamzin V, Tucker P, Wilmanns M, Colovos C, Meyer-Klaucke W, Munro AW, McLean KJ, Marshall KR, Leys D, Yang JK, Yoon HJ, Lee BI, Lee MG, Kwak JE, Han BW, Lee JY, Baek SH, Suh SW, Komen MM, Arcus VL, Baker EN, Lott JS, Jacobs W Jr, Alber T, Rupp B. (2003)
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology
Tuberculosis (Edinb) 83(4):223-249. doi: 10.1016/s1472-9792(03)00051-9
Europe PMC | doi
Zou P, Gautel M, Geerlof A, Wilmanns M, Koch MH, Svergun DI. (2003)
Solution scattering suggests cross-linking function of telethonin in the complex with titin
J. Biol. Chem. 278(4):2636-2644. doi: 10.1074/jbc.m210217200
Europe PMC | doi
2002
Gao M, Wilmanns M, Schulten K. (2002)
Steered molecular dynamics studies of titin I1 domain unfolding
Biophys. J. 83(6):3435-3445. doi: 10.1016/s0006-3495(02)75343-5
Europe PMC | doi
Douangamath A, Filipp FV, Klein AT, Barnett P, Zou P, Voorn-Brouwer T, Vega MC, Mayans OM, Sattler M, Distel B, Wilmanns M. (2002)
Topography for independent binding of alpha-helical and PPII-helical ligands to a peroxisomal SH3 domain
Mol. Cell 10(5):1007-1017. doi: 10.1016/s1097-2765(02)00749-9
Europe PMC | doi
Paavilainen VO, Merckel MC, Falck S, Ojala PJ, Pohl E, Wilmanns M, Lappalainen P. (2002)
Structural conservation between the actin monomer-binding sites of twinfilin and actin-depolymerizing factor (ADF)/cofilin
J. Biol. Chem. 277(45):43089-43095. doi: 10.1074/jbc.m208225200
Europe PMC | doi
Reményi A, Tomilin A, Schöler HR, Wilmanns M. (2002)
Differential activity by DNA-induced quarternary structures of POU transcription factors
Paper presented at the Meeting on Cell Signaling Transcription and Translation as Therapeutic Targets, LUXEMBOURG, GERMANY, JAN 30-FEB 02, 2002.Biochem. Pharmacol. 64(5-6):979-984. doi: 10.1016/s0006-2952(02)01164-4
Europe PMC | doi
Mayans O, Ivens A, Nissen LJ, Kirschner K, Wilmanns M. (2002)
Structural analysis of two enzymes catalysing reverse metabolic reactions implies common ancestry
EMBO J. 21(13):3245-3254. doi: 10.1093/emboj/cdf298
Europe PMC | doi
Pohl E, Brunner N, Wilmanns M, Hensel R. (2002)
The crystal structure of the allosteric non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeum Thermoproteus tenax
J. Biol. Chem. 277(22):19938-19945. doi: 10.1074/jbc.m112244200
Europe PMC | doi
Fazi B, Cope MJ, Douangamath A, Ferracuti S, Schirwitz K, Zucconi A, Drubin DG, Wilmanns M, Cesareni G, Castagnoli L. (2002)
Unusual binding properties of the SH3 domain of the yeast actin-binding protein Abp1: structural and functional analysis
J. Biol. Chem. 277(7):5290-5298. doi: 10.1074/jbc.m109848200
Europe PMC | doi
Ivens A, Mayans O, Szadkowski H, Jürgens C, Wilmanns M, Kirschner K. (2002)
Stabilization of a (betaalpha)8-barrel protein by an engineered disulfide bridge
Eur. J. Biochem. 269(4):1145-1153. doi: 10.1046/j.1432-1033.2002.02745.x
Europe PMC | doi
Wilmanns M. (2002)
Structural genomics in Europe and beyond - Shifting scientific directions at EMBL Hamburg
Acta Physica Polonica A 101(5):635-646.
Europe PMC
2001
Reményi A, Pohl E, Schöler HR, Wilmanns M. (2001)
Crystallization of redox-insensitive Oct1 POU domain with different DNA-response elements
Acta Crystallogr. D Biol. Crystallogr. 57(Pt 11):1634-1638. doi: 10.1107/s090744490101099x
Europe PMC | doi
Henn-Sax M, Höcker B, Wilmanns M, Sterner R. (2001)
Divergent evolution of (betaalpha)8-barrel enzymes
Biol. Chem. 382(9):1315-1320. doi: 10.1515/bc.2001.163
Europe PMC | doi
Reményi A, Tomilin A, Pohl E, Lins K, Philippsen A, Reinbold R, Schöler HR, Wilmanns M. (2001)
Differential dimer activities of the transcription factor Oct-1 by DNA-induced interface swapping
Mol. Cell 8(3):569-580. doi: 10.1016/s1097-2765(01)00336-7
Europe PMC | doi
Wilmanns M. (2001)
Matti Saraste (1949-2001)
Structure 9(9):769-770. doi: 10.1016/s0969-2126(01)00650-5
Europe PMC | doi
Höcker B, Jürgens C, Wilmanns M, Sterner R. (2001)
Stability, catalytic versatility and evolution of the (beta alpha)(8)-barrel fold
Curr. Opin. Biotechnol. 12(4):376-381. doi: 10.1016/s0958-1669(00)00230-5
Europe PMC | doi
Ivens A, Mayans O, Szadkowski H, Wilmanns M, Kirschner K. (2001)
Purification, characterization and crystallization of thermostable anthranilate phosphoribosyltransferase from Sulfolobus solfataricus
Eur. J. Biochem. 268(8):2246-2252. doi: 10.1046/j.1432-1327.2001.02102.x
Europe PMC | doi
Mayans O, Wuerges J, Canela S, Gautel M, Wilmanns M. (2001)
Structural evidence for a possible role of reversible disulphide bridge formation in the elasticity of the muscle protein titin
Structure 9(4):331-340. doi: 10.1016/s0969-2126(01)00591-3
Europe PMC | doi
Berisio R, Viguera A, Serrano L, Wilmanns M. (2001)
Atomic resolution structure of a mutant of the spectrin SH3 domain
Acta Crystallogr. D Biol. Crystallogr. 57(Pt 2):337-340. doi: 10.1107/s090744490001581x
Europe PMC | doi
2000
Tomilin A, Reményi A, Lins K, Bak H, Leidel S, Vriend G, Wilmanns M, Schöler HR. (2000)
Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration
Cell 103(6):853-864. doi: 10.1016/s0092-8674(00)00189-6
Europe PMC | doi
Lang D, Thoma R, Henn-Sax M, Sterner R, Wilmanns M. (2000)
Structural evidence for evolution of the beta/alpha barrel scaffold by gene duplication and fusion
Science 289(5484):1546-1550. doi: 10.1126/science.289.5484.1546
Europe PMC | doi
Jürgens C, Strom A, Wegener D, Hettwer S, Wilmanns M, Sterner R. (2000)
Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways
Proc. Natl. Acad. Sci. U.S.A. 97(18):9925-9930. doi: 10.1073/pnas.160255397
Europe PMC | doi
Wilmann M, Gautel M, Mayans O. (2000)
Activation of calcium/calmodulin regulated kinases
Cell. Mol. Biol. (Noisy-le-grand) 46(5):883-894.
Europe PMC
Wilmanns M, Gautel M. (2000)
Regulation von Proteinkinasen der MLCK-Familie
Biospektrum 5(3):198-201.
Brunner NA, Lang DA, Wilmanns M, Hensel R. (2000)
Crystallization and preliminary X-ray diffraction analysis of the NAD-dependent non--phosphorylating GAPDH of the hyperthermophilic archaeon Thermoproteus tenax
Acta Crystallogr. D Biol. Crystallogr. 56(Pt 1):89-91. doi: 10.1107/s0907444999014134
Europe PMC | doi
Wilmanns M. (2000)
Future structural biology applications with a free-electron laser - more than wild dreams?
J Synchrotron Radiat 7(Pt 1):41-46.
Europe PMC
1999
Knöchel T, Ivens A, Hester G, Gonzalez A, Bauerle R, Wilmanns M, Kirschner K, Jansonius JN. (1999)
The crystal structure of anthranilate synthase from Sulfolobus solfataricus: functional implications
Proc. Natl. Acad. Sci. U.S.A. 96(17):9479-9484. doi: 10.1073/pnas.96.17.9479
Europe PMC | doi
Thoma R, Obmolova G, Lang DA, Schwander M, Jenö P, Sterner R, Wilmanns M. (1999)
Efficient expression, purification and crystallisation of two hyperthermostable enzymes of histidine biosynthesis
FEBS Lett. 454(1-2):1-6. doi: 10.1016/s0014-5793(99)00757-7
Europe PMC | doi
Martínez JC, Viguera AR, Berisio R, Wilmanns M, Mateo PL, Filimonov VV, Serrano L. (1999)
Thermodynamic analysis of alpha-spectrin SH3 and two of its circular permutants with different loop lengths: discerning the reasons for rapid folding in proteins
Biochemistry 38(2):549-559. doi: 10.1021/bi981515u
Europe PMC | doi
Mayans O, Wilmanns M. (1999)
X-ray analysis of protein crystals with thin-plate morphology
J Synchrotron Radiat 6:1016-1020. doi: 10.1107/s0909049599004616
Europe PMC | doi
1998
Mayans O, van der Ven PF, Wilm M, Mues A, Young P, Fürst DO, Wilmanns M, Gautel M. (1998)
Structural basis for activation of the titin kinase domain during myofibrillogenesis
Nature 395(6705):863-869. doi: 10.1038/27603
Europe PMC | doi
Pisabarro MT, Serrano L, Wilmanns M. (1998)
Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions
J. Mol. Biol. 281(3):513-521. doi: 10.1006/jmbi.1998.1932
Europe PMC | doi
1996
Viguera AR, Serrano L, Wilmanns M. (1996)
Different folding transition states may result in the same native structure
Nat. Struct. Biol. 3(10):874-880. doi: 10.1038/nsb1096-874
Europe PMC | doi
1995
Hyvönen M, Macias MJ, Nilges M, Oschkinat H, Saraste M, Wilmanns M. (1995)
Structure of the binding site for inositol phosphates in a PH domain
EMBO J. 14(19):4676-4685. doi: 10.1002/j.1460-2075.1995.tb00149.x
Europe PMC | doi
Wilmanns M, Eisenberg D. (1995)
Inverse protein folding by the residue pair preference profile method: estimating the correctness of alignments of structurally compatible sequences
Protein Eng. 8(7):627-639. doi: 10.1093/protein/8.7.627
Europe PMC | doi
1994
Musacchio A, Saraste M, Wilmanns M. (1994)
High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides
Nat. Struct. Biol. 1(8):546-551. doi: 10.1038/nsb0894-546
Europe PMC | doi