EOM

Ensemble Optimization Method

Version 2.1 © ATSAS team 2007-2017

Written by G. Tria¹, P. Bernadó¹, E. Mylonas¹, M.V. Petoukhov¹ & D.I. Svergun^1
1European Molecular Biology Laboratory, Hamburg Outstation
EMBL c/o DESY
Notkestr. 85, Geb. 25a
22607 Hamburg
Germany

If you use EOM 2.x in your work, please cite:
Tria, G., Mertens, H. D. T., Kachala, M. & Svergun, D. I. (2015) Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering. IUCrJ 2, 207-217 DOI

If you use EOM 1.x in your work, please cite:
Bernado, P., Mylonas, E., Petoukhov, M.V., Blackledge, M., Svergun, D.I. (2007) Structural Characterization of Flexible Proteins Using Small-Angle X-ray Scattering. J. Am. Chem. Soc. 129(17), 5656-5664 DOI

Warning: When running EOM on short peptides it is recommended to use fixed size ensemble with 50 curves per ensemble and disallow repetitions. For details see
A. Sagar, C.M. Jeffries, M.V. Petoukhov, D.I. Svergun and P. Bernado (2021) Comment on the Optimal Parameters to Derive Intrinsically Disordered Protein Conformational Ensembles from Small-Angle X-ray Scattering Data Using the Ensemble Optimization Method
J. Chem. Theory Comput. 17(4), 2014-2021 DOI

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