EMBO Global Exchange Lecture Course

Structural and Biophysical Methods for Biological Macromolecules in Solution

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• Registration deadline: September 1, 2017
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Slides in PDF

• Introduction to the EMBO course - Dmitri Svergun
• Basics of X-ray and neutron scattering by solutions - Dmitri Svergun
• Neutron scattering - Jill Trewhella
• Structural research at A*Star - Frank Eisenhaber

• Statistics in the experimental practice of SAXS - Daniel Franke
• SAXS/SANS data processing and overall parameters - Haydyn Mertens
• Ab initio methods: how do they work? - Daniel Franke
• Atomic structure based modeling - Alejandro Panjkovich
• Sample preparation, characterization and light scattering methods: Part1 - Cy Jeffries
• Sample preparation, characterization and light scattering methods: Part2 - Cy Jeffries
• Fluorescence correlation spectroscopy (FCS) and FRET - Thorsten Wohland

• Introduction to basic NMR - Alexandre Bonvin
• Spectral Assignment and Structure Calculation - Lucia Banci
• NMR in a flipped class room: the use of the method in structural analyses of biological solids and solutions - Konstantin Pervushin
• Recent Advances in Biomolecular NMR - Lucia Banci
• NMR, docking and bioinformatics - Alexandre Bonvin

• Analytical ultracentrifugation - Olwyn Byron
• Joint use of SAXS and SANS - Jill Trewhella

• Mixtures, assemblies, flexible systems - Haydyn Mertens
• In-line purification of equilibrium mixtures - Cy Jeffries
• Processing and analysis of SEC-SAXS data - Alejandro Panjkovich
• Structural studies of protein fibrillation - Dmitri Svergun
• Combination of scattering and biophysical methods - Olwyn Byron

• Basics and progress of single particle reconstructions with cryo-EM: Part1 - Shashi Bhushan
• Basics and progress of single particle reconstructions with cryo-EM: Part2 - Shashi Bhushan
• Joint use of cryo-EM with other methods to characterize the Dengue and Zika Virus - Sheemei Lok
• Circular dichroism and spectroscopic methods - Jaume Torres
• Beauty of complementarity in structural biology - Gerhard Grueber
• Combining crystal structures and structures in solution: the example of the PAS-GGDEF-EAL region of RbdA from Pseudomonas aeruginosa, a protein important for the regulation of biofilm dispersal - Julien Lescar
• Advanced use of databases in the hybrid structural research - Kristina Djinovic-Carugo

• Simulating biomolecular function from motions across multiple scales: Part1 - Peter Bond
• Simulating biomolecular function from motions across multiple scales: Part2 - Peter Bond
• Applications of MX, SAXS and biophysical methods in the studies of sarcomeric proteins - Kristina Djinovic-Carugo
• Hybrid modelling using SAXS - Dmitri Svergun