SREFLEX

Flexible refinement of high-resolution models based on small angle X-ray scattering and normal mode analysis

© ATSAS team 2015-2017

Written by A. Panjkovich
European Molecular Biology Laboratory, Hamburg Outstation
EMBL c/o DESY
Notkestr. 85, Geb. 25a
22607 Hamburg
Germany

The SREFLEX program uses normal mode analysis (NMA) to estimate the flexibility of high-resolution models of biological macromolecules and improve their agreement with experimental small angle X-ray scattering (SAXS) data.

If you use SREFLEX in your work, please cite:
Panjkovich A. and Svergun D.I. (2016) Deciphering conformational transitions of proteins by small angle X-ray scattering and normal mode analysis. Phys. Chem. Chem. Phys., 18, 5707-5719

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